RefMet Compound Details

MW structure37494 (View MW Metabolite Database details)
RefMet nameCitrulline
Systematic name(2S)-2-amino-5-(carbamoylamino)pentanoic acid
Canonical SMILESNC(=O)NCCC[C@@H](N)C(O)=O
Exact mass175.0957View other entries in RefMet with this exact mass:   +/- 0.05 amu   +/- 0.1 amu   +/- 0.2 amu   +/- 0.5 amu
FormulaC6H13N3O3View other entries in RefMet with this formula
InChIInChI=1S/C6H13N3O3/c7-4(5(10)11)2-1-3-9-6(8)12/h4H,1-3,7H2,(H,10,11)(H3,8,9,12)/t4-/m0/s1
InChIKeyRHGKLRLOHDJJDR-BYPYZUCNSA-NView other enantiomers/diastereomers of this metabolite in RefMet
Super ClassOrganic acids
Main ClassAmino acids and peptides
Sub ClassAmino acids
Pubchem CID9750

Table of KEGG reactions in human pathways involving Citrulline

Rxn IDKEGG ReactionEnzyme
R01398 Carbamoyl phosphate + L-Ornithine <=> Orthophosphate + L-CitrullineCarbamoyl-phosphate:L-ornithine carbamoyltransferase
R00557 2 L-Arginine + 4 Oxygen + 3 NADPH + 3 H+ <=> 2 Nitric oxide + 2 L-Citrulline + 3 NADP+ + 4 H2OL-arginine,NADPH:oxygen oxidoreductase (nitric-oxide-forming)
R11711 2 L-Arginine + 3 Reduced flavodoxin + 4 Oxygen <=> 2 L-Citrulline + 2 Nitric oxide + 3 Oxidized flavodoxin + 4 H2OL-arginine,reduced-flavodoxin:oxygen oxidoreductase (nitric-oxide-forming)
R00552 L-Arginine + H2O <=> L-Citrulline + AmmoniaL-Arginine iminohydrolase

Table of KEGG human pathways containing Citrulline

Pathway IDHuman Pathway# of reactions
hsa00220 Arginine biosynthesis 3
hsa01230 Biosynthesis of amino acids 2
hsa00250 Alanine, aspartate and glutamate metabolism 1
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