RefMet Compound Details

RefMet ID, RefMet name, exact mass and formula
RefMet ID	RM0030190
RefMet name	Fructose 6-phosphate
Systematic name	{[(2R,3S,4S,5R)-3,4,5-trihydroxy-5-(hydroxymethyl)oxolan-2-yl]methoxy}phosphonic acid
Synonyms	PubChem Synonyms
Exact mass	260.029723 (neutral)	Calculate m/z: (Choose adduct) [M+H]+ [M+H-H2O]+ [M.]+ [M+2H]2+ [M+3H]3+ [M+4H]4+ [M+K]+ [M+2K]2+ [M+2K-H]+ [M+Na]+ [M+2Na]2+ [M+2Na-H]+ [M+Li]+ [M+2Li]2+ [M+NH4]+ [M.CH3]+ [M+Ag]+ [M+H+CH3OH]+ [M+H+CH3CN]+ [M+H+2CH3CN]+ [M+Na+CH3CN]+ [M.NaFormate+H]+ [M.NH4Formate+H]+ [M.TMSi]+ [M.tBuDMSi]+ [M+H-Hexose]+ [M+H-EtnP]+ [M+H-SerP]+ [M-H]- [M-H-H2O]- [M-CH3]- [M-2H]2- [M-3H]3- [M-4H]4- [M+Cl]- [M+OAc]- [M+Na-2H]- [M+K-2H]- [M.Formate]- [M.NaFormate-H]- [M.NH4Formate-H]- [M.F]- [M-H-Ser]- [M.HF2]- M(neutral)    View other RefMet entries with this exact (neutral) mass:   +/- 0.05 amu   +/- 0.1 amu   +/- 0.2 amu   +/- 0.5 amu
Formula	C6H13O9P	View other entries in RefMet with this formula
Molecular descriptors
Molfile	38436 (Download molfile/View MW Metabolite Database details)
InChI	InChI=1S/C6H13O9P/c7-2-6(10)5(9)4(8)3(15-6)1-14-16(11,12)13/h3-5,7-10H,1-2H2,(H2,11,12,13)/t3-,4-,5+,6-/m1/s1
InChIKey	BGWGXPAPYGQALX-ARQDHWQXSA-N	View other enantiomers/diastereomers of this metabolite in RefMet
SMILES	C([C@@H]1[C@H]([C@@H]([C@](CO)(O)O1)O)O)OP(=O)(O)O Run Tanimoto similarity search (with similarity coefficient >=0.6)
Chemical/Biochemical Classification
Super Class	Carbohydrates
Main Class	Monosaccharides
Sub Class	Hexose phosphates
Distribution of Fructose 6-phosphate in NMDR studies
Species	Plot Species distribution
Sample source	Plot Sample source(tissue) distribution
Platform	Platform (MS/NMR) used for detection
Chromatography	Chromatography methods used for detection
Studies	NMDR Studies reporting Fructose 6-phosphate
External Links
Pubchem CID	440641
ChEBI ID	16084
KEGG ID	C00085
HMDB ID	HMDB0003971
Chemspider ID	389526
Spectral data for Fructose 6-phosphate standards
NP-MRD ID(NMR)	View NMR spectra
MassBank(EU)	View MS spectra
Structural annotation level
Annotation level	1   (1:Known structure; 2:Known regiochemistry; 3:Partial structure; 4:Sum-composition)

Table of KEGG reactions in human pathways involving Fructose 6-phosphate

Rxn ID	KEGG Reaction	Enzyme
R00756	ATP + D-Fructose 6-phosphate <=> ADP + D-Fructose 1,6-bisphosphate	ATP:D-fructose-6-phosphate 1-phosphotransferase
R00760	ATP + D-Fructose <=> ADP + D-Fructose 6-phosphate	ATP:D-fructose 6-phosphotransferase
R00761	D-Fructose 6-phosphate + Orthophosphate <=> Acetyl phosphate + D-Erythrose 4-phosphate + H2O	D-fructose-6-phosphate D-erythrose-4-phosphate-lyase (adding phosphate
R00762	D-Fructose 1,6-bisphosphate + H2O <=> D-Fructose 6-phosphate + Orthophosphate	D-Fructose-1,6-bisphosphate 1-phosphohydrolase
R00765	D-Glucosamine 6-phosphate + H2O <=> D-Fructose 6-phosphate + Ammonia	D-glucosamine-6-phosphate aminohydrolase (ketol isomerizing)
R00768	L-Glutamine + D-Fructose 6-phosphate <=> L-Glutamate + D-Glucosamine 6-phosphate	L-glutamine:D-fructose-6-phosphate isomerase (deaminating)
R00771	D-Glucose 6-phosphate <=> D-Fructose 6-phosphate	D-glucose-6-phosphate aldose-ketose-isomerase
R00867	ATP + D-Fructose <=> ADP + beta-D-Fructose 6-phosphate	ATP:D-fructose 6-phosphotransferase
R01067	D-Fructose 6-phosphate + D-Glyceraldehyde 3-phosphate <=> D-Erythrose 4-phosphate + D-Xylulose 5-phosphate	D-Fructose 6-phosphate:D-glyceraldehyde-3-phosphate glycolaldehyde transferase
R01819	D-Mannose 6-phosphate <=> beta-D-Fructose 6-phosphate	D-mannose-6-phosphate aldose-ketose-isomerase
R01830	beta-D-Fructose 6-phosphate + D-Glyceraldehyde 3-phosphate <=> D-Erythrose 4-phosphate + D-Xylulose 5-phosphate	beta-D-Fructose 6-phosphate:D-glyceraldehyde-3-phosphate glycolaldehyde transferase
R02073	Diphosphate + beta-D-Fructose 6-phosphate <=> Orthophosphate + beta-D-Fructose 1,6-bisphosphate	diphosphate:beta-D-fructose-6-phosphate 1-phosphotransferase
R02731	beta-D-Fructose 2,6-bisphosphate + H2O <=> beta-D-Fructose 6-phosphate + Orthophosphate	D-Fructose-2,6-bisphosphate 2-phosphohydrolase
R02732	ATP + beta-D-Fructose 6-phosphate <=> ADP + beta-D-Fructose 2,6-bisphosphate	ATP:D-fructose-6-phosphate 2-phosphotransferase
R02740	alpha-D-Glucose 6-phosphate <=> beta-D-Fructose 6-phosphate	alpha-D-Glucose 6-phosphate ketol-isomerase
R03321	beta-D-Glucose 6-phosphate <=> beta-D-Fructose 6-phosphate	beta-D-Glucose 6-phosphate ketol-isomerase
R03920	ATP + beta-D-Fructose <=> ADP + beta-D-Fructose 6-phosphate	ATP:D-fructose 6-phosphotransferase
R04779	ATP + beta-D-Fructose 6-phosphate <=> ADP + beta-D-Fructose 1,6-bisphosphate	ATP:D-fructose-6-phosphate 1-phosphotransferase
R04780	beta-D-Fructose 1,6-bisphosphate + H2O <=> beta-D-Fructose 6-phosphate + Orthophosphate	beta-D-Fructose 1,6-bisphosphate 1-phosphohydrolase
R05805	ADP + D-Fructose 6-phosphate <=> AMP + D-Fructose 1,6-bisphosphate	ADP:D-fructose-6-phosphate 1-phosphotransferase
R09084	beta-D-Fructose 6-phosphate + ADP <=> beta-D-Fructose 1,6-bisphosphate + AMP	ADP:D-fructose-6-phosphate 1-phosphotransferase

Table of KEGG human pathways containing Fructose 6-phosphate

Pathway ID	Human Pathway	# of reactions
hsa01100	Metabolic pathways	7
hsa00520	Amino sugar and nucleotide sugar metabolism	5
hsa00030	Pentose phosphate pathway	5
hsa00051	Fructose and mannose metabolism	5
hsa00010	Glycolysis / Gluconeogenesis	4
hsa01200	Carbon metabolism	4
hsa01230	Biosynthesis of amino acids	4
hsa00500	Starch and sucrose metabolism	2
hsa00250	Alanine, aspartate and glutamate metabolism	1