RefMet Compound Details

MW structure37095 (View MW Metabolite Database details)
RefMet nameFumaric acid
Systematic name(2E)-but-2-enedioic acid
SMILESOC(=O)/C=C/C(O)=O
Exact mass116.010960 (neutral)
Calculate m/z:   
View other RefMet entries with this exact (neutral) mass:   +/- 0.05 amu   +/- 0.1 amu   +/- 0.2 amu   +/- 0.5 amu
FormulaC4H4O4View other entries in RefMet with this formula
InChIInChI=1S/C4H4O4/c5-3(6)1-2-4(7)8/h1-2H,(H,5,6)(H,7,8)/b2-1+
InChIKeyVZCYOOQTPOCHFL-OWOJBTEDSA-NView other enantiomers/diastereomers of this metabolite in RefMet
Super ClassOrganic acids
Main ClassTCA acids
Sub ClassTCA acids
Pubchem CID444972
Annotation level1   (1:Known structure; 2:Known regiochemistry; 3:Partial structure; 4:Sum-composition)
Human quantitationView measurements in targeted assays on human samples

Table of KEGG reactions in human pathways involving Fumaric acid

Rxn IDKEGG ReactionEnzyme
R00402 Succinate + NAD+ <=> Fumarate + NADH + H+succinate:NAD+ oxidoreductase
R01082 (S)-Malate <=> Fumarate + H2O(S)-malate hydro-lyase (fumarate-forming)
R02164 Quinone + Succinate <=> Hydroquinone + Fumaratesuccinate:quinone oxidoreductase
R10660 Fumarate + Coenzyme M + Coenzyme B <=> Succinate + Coenzyme M 7-mercaptoheptanoylthreonine-phosphate heterodisulfidefumarate CoM:CoB oxidoreductase (succinate forming)

Table of KEGG human pathways containing Fumaric acid

Pathway IDHuman Pathway# of reactions
hsa00350 Tyrosine metabolism 2
hsa00020 Citrate cycle (TCA cycle) 2
hsa00250 Alanine, aspartate and glutamate metabolism 1
hsa01230 Biosynthesis of amino acids 1
hsa00620 Pyruvate metabolism 1
hsa01200 Carbon metabolism 1
hsa00220 Arginine biosynthesis 1
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