RefMet Compound Details

MW structure	37700 (View MW Metabolite Database details)
RefMet name	GTP
Systematic name	({[({[(2R,3S,4R,5R)-5-(2-amino-6-oxo-6,9-dihydro-1H-purin-9-yl)-3,4-dihydroxyoxolan-2-yl]methoxy}(hydroxy)phosphoryl)oxy](hydroxy)phosphoryl}oxy)phosphonic acid
SMILES	C([C@@H]1[C@H]([C@H]([C@H](n2cnc3c2nc(N)[nH]c3=O)O1)O)O)OP(=O)(O)OP(=O)(O)OP(=O)(O)O   Run Tanimoto similarity search (with similarity coefficient >=0.6)
Exact mass	522.990669 (neutral)	Calculate m/z: (Choose adduct) [M+H]+ [M+H-H2O]+ [M.]+ [M+2H]2+ [M+3H]3+ [M+4H]4+ [M+K]+ [M+2K]2+ [M+2K-H]+ [M+Na]+ [M+2Na]2+ [M+2Na-H]+ [M+Li]+ [M+2Li]2+ [M+NH4]+ [M.CH3]+ [M+Ag]+ [M+H+CH3OH]+ [M+H+CH3CN]+ [M+H+2CH3CN]+ [M+Na+CH3CN]+ [M.NaFormate+H]+ [M.NH4Formate+H]+ [M.TMSi]+ [M.tBuDMSi]+ [M+H-Hexose]+ [M+H-EtnP]+ [M+H-SerP]+ [M-H]- [M-H-H2O]- [M-CH3]- [M-2H]2- [M-3H]3- [M-4H]4- [M+Cl]- [M+OAc]- [M+Na-2H]- [M+K-2H]- [M.Formate]- [M.NaFormate-H]- [M.NH4Formate-H]- [M.F]- [M-H-Ser]- [M.HF2]- M(neutral)    View other RefMet entries with this exact (neutral) mass:   +/- 0.05 amu   +/- 0.1 amu   +/- 0.2 amu   +/- 0.5 amu
Formula	C10H16N5O14P3	View other entries in RefMet with this formula
InChI	InChI=1S/C10H16N5O14P3/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(17)5(16)3(27-9)1-26-31(22,23)29-32(24,25)28-30(19,20)21/h2-3,5-6,9,1 6-17H,1H2,(H,22,23)(H,24,25)(H2,19,20,21)(H3,11,13,14,18)/t3-,5-,6-,9-/m1/s1
InChIKey	XKMLYUALXHKNFT-UUOKFMHZSA-N	View other enantiomers/diastereomers of this metabolite in RefMet
Super Class	Nucleic acids
Main Class	Purines
Sub Class	Purine rNTP
Pubchem CID	135398633
Annotation level	1   (1:Known structure; 2:Known regiochemistry; 3:Partial structure; 4:Sum-composition)

Table of KEGG reactions in human pathways involving GTP

Rxn ID	KEGG Reaction	Enzyme
R00428	GTP + H2O <=> Formamidopyrimidine nucleoside triphosphate	GTP 8,9-hydrolase
R00434	GTP <=> 3',5'-Cyclic GMP + Diphosphate	GTP diphosphate-lyase (cyclizing
R00330	ATP + GDP <=> ADP + GTP	ATP:GDP phosphotransferase
R00424	GTP + H2O <=> 7,8-Dihydroneopterin 3'-triphosphate + Formate	GTP 7,8-8,9-dihydrolase
R00426	GTP + H2O <=> GMP + Diphosphate	GTP diphosphohydrolase (diphosphate-forming)
R09394	GTP + S-Adenosyl-L-methionine + Reduced acceptor <=> (8S)-3',8-Cyclo-7,8-dihydroguanosine 5'-triphosphate + 5'-Deoxyadenosine + L-Methionine + Acceptor	GTP 3',8-cyclase [(8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate-forming]
R00430	GTP + Pyruvate <=> GDP + Phosphoenolpyruvate	GTP:pyruvate 2-O-phosphotransferase
R00335	GTP + H2O <=> GDP + Orthophosphate	GTP phosphohydrolase
R01232	P1,P4-Bis(5'-guanosyl) tetraphosphate + H2O <=> GTP + GMP	P1,P4-bis(5'-guanosyl)-tetraphosphate guanylylhydrolase

Table of KEGG human pathways containing GTP

Pathway ID	Human Pathway	# of reactions
hsa00230	Purine metabolism	6
hsa00790	Folate biosynthesis	2
hsa01240	Biosynthesis of cofactors	1