RefMet Compound Details

MW structure	37101 (View MW Metabolite Database details)
RefMet name	Glutamic acid
Systematic name	(2S)-2-aminopentanedioic acid
SMILES	C(CC(=O)O)[C@@H](C(=O)O)N   Run Tanimoto similarity search (with similarity coefficient >=0.6)
Exact mass	147.053159 (neutral)	Calculate m/z: (Choose adduct) [M+H]+ [M+H-H2O]+ [M.]+ [M+2H]2+ [M+3H]3+ [M+4H]4+ [M+K]+ [M+2K]2+ [M+2K-H]+ [M+Na]+ [M+2Na]2+ [M+2Na-H]+ [M+Li]+ [M+2Li]2+ [M+NH4]+ [M.CH3]+ [M+Ag]+ [M+H+CH3OH]+ [M+H+CH3CN]+ [M+H+2CH3CN]+ [M+Na+CH3CN]+ [M.NaFormate+H]+ [M.NH4Formate+H]+ [M.TMSi]+ [M.tBuDMSi]+ [M+H-Hexose]+ [M+H-EtnP]+ [M+H-SerP]+ [M-H]- [M-H-H2O]- [M-CH3]- [M-2H]2- [M-3H]3- [M-4H]4- [M+Cl]- [M+OAc]- [M+Na-2H]- [M+K-2H]- [M.Formate]- [M.NaFormate-H]- [M.NH4Formate-H]- [M.F]- [M-H-Ser]- [M.HF2]- M(neutral)    View other RefMet entries with this exact (neutral) mass:   +/- 0.05 amu   +/- 0.1 amu   +/- 0.2 amu   +/- 0.5 amu
Formula	C5H9NO4	View other entries in RefMet with this formula
InChI	InChI=1S/C5H9NO4/c6-3(5(9)10)1-2-4(7)8/h3H,1-2,6H2,(H,7,8)(H,9,10)/t3-/m0/s1
InChIKey	WHUUTDBJXJRKMK-VKHMYHEASA-N	View other enantiomers/diastereomers of this metabolite in RefMet
Super Class	Organic acids
Main Class	Amino acids and peptides
Sub Class	Amino acids
Pubchem CID	33032
Annotation level	1   (1:Known structure; 2:Known regiochemistry; 3:Partial structure; 4:Sum-composition)

Table of KEGG reactions in human pathways involving Glutamic acid

Rxn ID	KEGG Reaction	Enzyme
R00239	ATP + L-Glutamate <=> ADP + L-Glutamyl 5-phosphate	ATP:L-glutamate 5-phosphotransferase
R00708	(S)-1-Pyrroline-5-carboxylate + NADP+ + 2 H2O <=> L-Glutamate + NADPH + H+	(S)-1-pyrroline-5-carboxylate:NADP+ oxidoreductase
R02287	5-Formiminotetrahydrofolate + L-Glutamate <=> Tetrahydrofolate + N-Formimino-L-glutamate	5-Formiminotetrahydrofolate:L-glutamate N-formiminotransferase
R00093	2 L-Glutamate + NAD+ <=> L-Glutamine + 2-Oxoglutarate + NADH + H+	L-glutamate:NAD+ oxidoreductase (transaminating)
R00251	ATP + 5-Oxoproline + 2 H2O <=> ADP + Orthophosphate + L-Glutamate	5-oxo-L-proline amidohydrolase (ATP-hydrolysing)
R00253	ATP + L-Glutamate + Ammonia <=> ADP + Orthophosphate + L-Glutamine	L-Glutamate:ammonia ligase (ADP-forming)
R00114	2 L-Glutamate + NADP+ <=> L-Glutamine + 2-Oxoglutarate + NADPH + H+	L-glutamate:NADP+ oxidoreductase (transaminating)
R00245	L-Glutamate 5-semialdehyde + NAD+ + H2O <=> L-Glutamate + NADH + H+	L-glutamate gamma-semialdehyde:NAD+ oxidoreductase
R00259	Acetyl-CoA + L-Glutamate <=> CoA + N-Acetyl-L-glutamate	acetyl-CoA:L-glutamate N-acetyltransferase
R00243	L-Glutamate + NAD+ + H2O <=> 2-Oxoglutarate + Ammonia + NADH + H+	L-glutamate:NAD+ oxidoreductase (deaminating)
R00256	L-Glutamine + H2O <=> L-Glutamate + Ammonia	L-glutamine amidohydrolase
R02285	N-Formimino-L-glutamate + H2O <=> L-Glutamate + Formamide	N-Formimino-L-glutamate formiminohydrolase
R00355	L-Aspartate + 2-Oxoglutarate <=> Oxaloacetate + L-Glutamate	L-Aspartate:2-oxoglutarate aminotransferase
R00258	L-Alanine + 2-Oxoglutarate <=> Pyruvate + L-Glutamate	L-Alanine:2-oxoglutarate aminotransferase
R00248	L-Glutamate + NADP+ + H2O <=> 2-Oxoglutarate + Ammonia + NADPH + H+	L-glutamate:NADP+ oxidoreductase (deaminating)
R00707	(S)-1-Pyrroline-5-carboxylate + NAD+ + 2 H2O <=> L-Glutamate + NADH + H+	(S)-1-pyrroline-5-carboxylate:NAD+ oxidoreductase
R05578	tRNA(Glu) + L-Glutamate + ATP <=> L-Glutamyl-tRNA(Glu) + Diphosphate + AMP	L-glutamate:tRNA(Glu) ligase (AMP-forming)
R00261	L-Glutamate <=> 4-Aminobutanoate + CO2	L-glutamate 1-carboxy-lyase (4-aminobutanoate-forming)

Table of KEGG human pathways containing Glutamic acid

Pathway ID	Human Pathway	# of reactions
hsa01100	Metabolic pathways	7
hsa00250	Alanine, aspartate and glutamate metabolism	5
hsa00330	Arginine and proline metabolism	4
hsa00220	Arginine biosynthesis	3
hsa01230	Biosynthesis of amino acids	3
hsa00260	Glycine, serine and threonine metabolism	2
hsa01200	Carbon metabolism	2
hsa01210	2-Oxocarboxylic acid metabolism	2
hsa00480	Glutathione metabolism	2
hsa00910	Nitrogen metabolism	1
hsa00970	Aminoacyl-tRNA biosynthesis	1
hsa00340	Histidine metabolism	1
hsa00650	Butanoate metabolism	1
hsa00670	One carbon pool by folate	1
hsa00860	Porphyrin and chlorophyll metabolism	1