RefMet Compound Details

RefMet ID, RefMet name, exact mass and formula
RefMet ID	RM0040233
RefMet name	Glyoxylic acid
Systematic name	2-oxoacetic acid
Synonyms	PubChem Synonyms
Exact mass	74.000395 (neutral)	Calculate m/z: (Choose adduct) [M+H]+ [M+H-H2O]+ [M.]+ [M+2H]2+ [M+3H]3+ [M+4H]4+ [M+K]+ [M+2K]2+ [M+2K-H]+ [M+Na]+ [M+2Na]2+ [M+2Na-H]+ [M+Li]+ [M+2Li]2+ [M+NH4]+ [M.CH3]+ [M+Ag]+ [M+H+CH3OH]+ [M+H+CH3CN]+ [M+H+2CH3CN]+ [M+Na+CH3CN]+ [M.NaFormate+H]+ [M.NH4Formate+H]+ [M.TMSi]+ [M.tBuDMSi]+ [M+H-Hexose]+ [M+H-EtnP]+ [M+H-SerP]+ [M-H]- [M-H-H2O]- [M-CH3]- [M-2H]2- [M-3H]3- [M-4H]4- [M+Cl]- [M+OAc]- [M+Na-2H]- [M+K-2H]- [M.Formate]- [M.NaFormate-H]- [M.NH4Formate-H]- [M.F]- [M-H-Ser]- [M.HF2]- M(neutral)    View other RefMet entries with this exact (neutral) mass:   +/- 0.05 amu   +/- 0.1 amu   +/- 0.2 amu   +/- 0.5 amu
Formula	C2H2O3	View other entries in RefMet with this formula
Molecular descriptors
Molfile	37082 (Download molfile/View MW Metabolite Database details)
InChI	InChI=1S/C2H2O3/c3-1-2(4)5/h1H,(H,4,5)
InChIKey	HHLFWLYXYJOTON-UHFFFAOYSA-N	View other enantiomers/diastereomers of this metabolite in RefMet
SMILES	C(=O)C(=O)O Run Tanimoto similarity search (with similarity coefficient >=0.6)
Chemical/Biochemical Classification
Super Class	Organic acids
Main Class	Carboxylic acids
Sub Class	Carboxylic acids
Distribution of Glyoxylic acid in NMDR studies
Species	Plot Species distribution
Sample source	Plot Sample source(tissue) distribution
Platform	Platform (MS/NMR) used for detection
Chromatography	Chromatography methods used for detection
Studies	NMDR Studies reporting Glyoxylic acid
External Links
Pubchem CID	760
ChEBI ID	16891
KEGG ID	C00048
HMDB ID	HMDB0000119
Chemspider ID	740
MetaCyc ID	GLYOX
EPA CompTox	DTXCID401594
Spectral data for Glyoxylic acid standards
NP-MRD ID(NMR)	View NMR spectra
MassBank(EU)	View MS spectra
Structural annotation level
Annotation level	1   (1:Known structure; 2:Known regiochemistry; 3:Partial structure; 4:Sum-composition)

Table of KEGG reactions in human pathways involving Glyoxylic acid

Rxn ID	KEGG Reaction	Enzyme
R00366	Glycine + H2O + Oxygen <=> Glyoxylate + Ammonia + Hydrogen peroxide	glycine:oxygen oxidoreductase (deaminating)
R00372	Glycine + 2-Oxoglutarate <=> Glyoxylate + L-Glutamate	Glycine:2-oxoglutarate aminotransferase
R00465	Glycolate + NADP+ <=> Glyoxylate + NADPH + H+	glycolate:NADP+ oxidoreductase
R00470	4-Hydroxy-2-oxoglutarate <=> Pyruvate + Glyoxylate	4-hydroxy-2-oxoglutarate glyoxylate-lyase (pyruvate-forming)
R00471	(4R)-4-Hydroxy-2-oxoglutarate <=> Pyruvate + Glyoxylate	4-hydroxy-2-oxoglutarate glyoxylate-lyase (pyruvate-forming)
R00475	Glycolate + Oxygen <=> Glyoxylate + Hydrogen peroxide	glycolate:oxygen 2-oxidoreductase
R00476	Glycolate + Acceptor <=> Glyoxylate + Reduced acceptor	glycolate:acceptor 2-oxidoreductase
R00717	Glycolate + NAD+ <=> Glyoxylate + NADH + H+	Glycolate:NAD+ oxidoreductase

Table of KEGG human pathways containing Glyoxylic acid

Pathway ID	Human Pathway	# of reactions
hsa00260	Glycine, serine and threonine metabolism	4
hsa00630	Glyoxylate and dicarboxylate metabolism	4
hsa01100	Metabolic pathways	3
hsa00330	Arginine and proline metabolism	1
hsa01200	Carbon metabolism	1