RefMet Compound Details

MW structure37171 (View MW Metabolite Database details)
RefMet namePyroglutamic acid
Systematic name(2S)-5-oxopyrrolidine-2-carboxylic acid
SMILESOC(=O)[C@@H]1CCC(=O)N1
Sum CompositionPyroglutamic acid View other entries in RefMet with this sum composition
Exact mass129.042594 (neutral)
Calculate m/z:   
View other RefMet entries with this exact (neutral) mass:   +/- 0.05 amu   +/- 0.1 amu   +/- 0.2 amu   +/- 0.5 amu
FormulaC5H7NO3View other entries in RefMet with this formula
InChIInChI=1S/C5H7NO3/c7-4-2-1-3(6-4)5(8)9/h3H,1-2H2,(H,6,7)(H,8,9)/t3-/m0/s1
InChIKeyODHCTXKNWHHXJC-VKHMYHEASA-NView other enantiomers/diastereomers of this metabolite in RefMet
Super ClassOrganoheterocyclic compounds
Main ClassPyrroline carboxylic acids
Sub ClassPyrroline carboxylic acids
Pubchem CID7405
Annotation level1   (1:Known structure; 2:Known regiochemistry; 3:Partial structure; 4:Sum-composition)

Table of KEGG reactions in human pathways involving Pyroglutamic acid

Rxn IDKEGG ReactionEnzyme
R03749 (5-L-Glutamyl)-L-amino acid <=> 5-Oxoproline + L-Amino acid(5-L-glutamyl)-L-amino-acid gamma-glutamyl cyclotransferase (5-oxoproline-forming)
R00251 ATP + 5-Oxoproline + 2 H2O <=> ADP + Orthophosphate + L-Glutamate5-oxo-L-proline amidohydrolase (ATP-hydrolysing)

Table of KEGG human pathways containing Pyroglutamic acid

Pathway IDHuman Pathway# of reactions
hsa00480 Glutathione metabolism 4
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