RefMet Compound Details

MW structure37123 (View MW Metabolite Database details)
RefMet nameSerine
Systematic name(2S)-2-amino-3-hydroxypropanoic acid
Canonical SMILESN[C@@H](CO)C(O)=O
Exact mass105.0426View other entries in RefMet with this exact mass:   +/- 0.05 amu   +/- 0.1 amu   +/- 0.2 amu   +/- 0.5 amu
FormulaC3H7NO3View other entries in RefMet with this formula
InChIInChI=1S/C3H7NO3/c4-2(1-5)3(6)7/h2,5H,1,4H2,(H,6,7)/t2-/m0/s1
InChIKeyMTCFGRXMJLQNBG-REOHCLBHSA-NView other enantiomers/diastereomers of this metabolite in RefMet
Super ClassOrganic acids
Main ClassAmino acids and peptides
Sub ClassAmino acids
Pubchem CID5951

Table of KEGG reactions in human pathways involving Serine

Rxn IDKEGG ReactionEnzyme
R00589 L-Serine <=> D-Serineserine racemase
R12342 ADP + L-Serine <=> AMP + O-Phospho-L-serineADP:L-serine 3-phosphotransferase
R00891 L-Serine + Hydrogen sulfide <=> L-Cysteine + H2OL-serine hydro-lyase (adding hydrogen sulfide, L-cysteine-forming)
R00582 O-Phospho-L-serine + H2O <=> L-Serine + OrthophosphateO-phospho-L-serine phosphohydrolase
R00590 L-Serine <=> Dehydroalanine + H2OL-serine hydro-lyase
R00945 5,10-Methylenetetrahydrofolate + Glycine + H2O <=> Tetrahydrofolate + L-Serine5,10-Methylenetetrahydrofolate:glycine hydroxymethyltransferase
R09099 L-Serine + 5,6,7,8-Tetrahydromethanopterin <=> 5,10-Methylenetetrahydromethanopterin + Glycine + H2O5,10-methylenetetrahydromethanopterin:glycine hydroxymethyltransferase
R12344 ATP + L-Serine <=> ADP + O-Phospho-L-serineATP:L-serine 3-phosphotransferase
R00220 L-Serine <=> Pyruvate + AmmoniaL-serine ammonia-lyase

Table of KEGG human pathways containing Serine

Pathway IDHuman Pathway# of reactions
hsa00260 Glycine, serine and threonine metabolism 8
hsa01200 Carbon metabolism 4
hsa01230 Biosynthesis of amino acids 4
hsa00630 Glyoxylate and dicarboxylate metabolism 2
hsa00270 Cysteine and methionine metabolism 2
hsa00670 One carbon pool by folate 1
hsa00600 Sphingolipid metabolism 1
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