RefMet Compound Details

RefMet ID, RefMet name, exact mass and formula
RefMet ID	RM0135933
RefMet name	Uridine
Systematic name	1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione
Synonyms	PubChem Synonyms
Exact mass	244.069538 (neutral)	Calculate m/z: (Choose adduct) [M+H]+ [M+H-H2O]+ [M.]+ [M+2H]2+ [M+3H]3+ [M+4H]4+ [M+K]+ [M+2K]2+ [M+2K-H]+ [M+Na]+ [M+2Na]2+ [M+2Na-H]+ [M+Li]+ [M+2Li]2+ [M+NH4]+ [M.CH3]+ [M+Ag]+ [M+H+CH3OH]+ [M+H+CH3CN]+ [M+H+2CH3CN]+ [M+Na+CH3CN]+ [M.NaFormate+H]+ [M.NH4Formate+H]+ [M.TMSi]+ [M.tBuDMSi]+ [M+H-Hexose]+ [M+H-EtnP]+ [M+H-SerP]+ [M-H]- [M-H-H2O]- [M-CH3]- [M-2H]2- [M-3H]3- [M-4H]4- [M+Cl]- [M+OAc]- [M+Na-2H]- [M+K-2H]- [M.Formate]- [M.NaFormate-H]- [M.NH4Formate-H]- [M.F]- [M-H-Ser]- [M.HF2]- M(neutral)    View other RefMet entries with this exact (neutral) mass:   +/- 0.05 amu   +/- 0.1 amu   +/- 0.2 amu   +/- 0.5 amu
Formula	C9H12N2O6	View other entries in RefMet with this formula
Molecular descriptors
Molfile	37190 (Download molfile/View MW Metabolite Database details)
InChI	InChI=1S/C9H12N2O6/c12-3-4-6(14)7(15)8(17-4)11-2-1-5(13)10-9(11)16/h1-2,4,6-8,12,14-15H,3H2,(H,10,13,16)/t4-,6-,7-,8-/m1/s1
InChIKey	DRTQHJPVMGBUCF-XVFCMESISA-N	View other enantiomers/diastereomers of this metabolite in RefMet
SMILES	c1cn([C@H]2[C@@H]([C@@H]([C@@H](CO)O2)O)O)c(=O)[nH]c1=O Run Tanimoto similarity search (with similarity coefficient >=0.6)
Chemical/Biochemical Classification
Super Class	Nucleic acids
Main Class	Pyrimidines
Sub Class	Pyrimidine ribonucleosides
Distribution of Uridine in NMDR studies
Species	Plot Species distribution
Sample source	Plot Sample source(tissue) distribution
Platform	Platform (MS/NMR) used for detection
Chromatography	Chromatography methods used for detection
Studies	NMDR Studies reporting Uridine
External Links
Pubchem CID	6029
ChEBI ID	16704
KEGG ID	C00299
HMDB ID	HMDB0000296
Chemspider ID	5807
MetaCyc ID	URIDINE
EPA CompTox	DTXCID50219180
Spectral data for Uridine standards
BMRB ID(NMR)	View NMR spectra
NP-MRD ID(NMR)	View NMR spectra
MassBank(EU)	View MS spectra
Structural annotation level
Annotation level	1   (1:Known structure; 2:Known regiochemistry; 3:Partial structure; 4:Sum-composition)

Table of KEGG reactions in human pathways involving Uridine

Rxn ID	KEGG Reaction	Enzyme
R00963	UMP + H2O <=> Uridine + Orthophosphate	uridine 5'-monophosphate phosphohydrolase
R00964	ATP + Uridine <=> ADP + UMP	ATP:uridine 5'-phosphotransferase
R00967	UTP + Uridine <=> UDP + UMP	UTP:uridine 5'-phosphotransferase
R00968	GTP + Uridine <=> GDP + UMP	GTP:uridine 5'-phosphotransferase
R00970	ITP + Uridine <=> IDP + UMP	ITP:uridine 5'-phosphotransferase
R01080	Uridine + H2O <=> Uracil + D-Ribose	Uridine ribohydrolase
R01549	dATP + Uridine <=> dADP + UMP	dATP:uridine 5'-phosphotransferase
R01876	Uridine + Orthophosphate <=> Uracil + alpha-D-Ribose 1-phosphate	uridine:phosphate alpha-D-ribosyltransferase
R01878	Cytidine + H2O <=> Uridine + Ammonia	Cytidine aminohydrolase
R01880	dGTP + Uridine <=> dGDP + UMP	dGTP:uridine 5'-phosphotransferase
R02097	dTTP + Uridine <=> dTDP + UMP	dTTP:uridine 5'-phosphotransferase
R02327	dCTP + Uridine <=> dCDP + UMP	dCTP:uridine 5'-phosphotransferase
R02332	dUTP + Uridine <=> dUDP + UMP	dUTP:uridine 5'-phosphotransferase

Table of KEGG human pathways containing Uridine

Pathway ID	Human Pathway	# of reactions
hsa00240	Pyrimidine metabolism	5
hsa01100	Metabolic pathways	2
hsa01232	Nucleotide metabolism	2