RefMet Compound Details

MW structure37779 (View MW Metabolite Database details)
RefMet namedUMP
Systematic name{[(2R,3S,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-3-hydroxyoxolan-2-yl]methoxy}phosphonic acid
Canonical SMILESO[C@@H]1C[C@H](O[C@H]1COP(O)(O)=O)N1C=CC(=O)NC1=O
Exact mass308.0410View other entries in RefMet with this exact mass:   +/- 0.05 amu   +/- 0.1 amu   +/- 0.2 amu   +/- 0.5 amu
FormulaC9H13N2O8PView other entries in RefMet with this formula
InChIInChI=1S/C9H13N2O8P/c12-5-3-8(11-2-1-7(13)10-9(11)14)19-6(5)4-18-20(15,16)17/h1-2,5-6,8,12H,3-4H2,(H,10,13,14)(H2,15,16,17)/t5-,6+,8+/m0/s1
InChIKeyJSRLJPSBLDHEIO-SHYZEUOFSA-NView other enantiomers/diastereomers of this metabolite in RefMet
Super ClassNucleic acids
Main ClassPyrimidines
Sub classPyrimidine deoxyribonucleoside monophosphates
Pubchem CID65063

Table of KEGG reactions in human pathways involving dUMP

Rxn IDKEGG ReactionEnzyme
R02099 ATP + Deoxyuridine <=> ADP + dUMPATP:deoxyuridine 5'-phosphotransferase
R02101 dUMP + 5,10-Methylenetetrahydrofolate <=> Dihydrofolate + dTMP5,10-Methylenetetrahydrofolate:dUMP C-methyltransferase
R02100 dUTP + H2O <=> dUMP + DiphosphatedUTP nucleotidohydrolase
R01663 dCMP + H2O <=> dUMP + AmmoniadCMP aminohydrolase
R02098 ATP + dUMP <=> ADP + dUDPATP:dUMP phosphotransferase
R02102 dUMP + H2O <=> Deoxyuridine + Orthophosphate2'-deoxyuridine 5'-monophosphate phosphohydrolase

Table of KEGG human pathways containing dUMP

Pathway IDHuman Pathway# of reactions
hsa00240 Pyrimidine metabolism 6
hsa00670 One carbon pool by folate 1
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