RefMet Compound Details

MW structure73611 (View MW Metabolite Database details)
RefMet nametrans-4-Hydroxyproline
Systematic nameTrans-4-hydroxy-L-proline
Exact mass131.058244 (neutral)
Calculate m/z:   
View other RefMet entries with this exact (neutral) mass:   +/- 0.05 amu   +/- 0.1 amu   +/- 0.2 amu   +/- 0.5 amu
FormulaC5H9NO3View other entries in RefMet with this formula
InChIKeyPMMYEEVYMWASQN-DMTCNVIQSA-NView other enantiomers/diastereomers of this metabolite in RefMet
Super ClassOrganic acids
Main ClassAmino acids and peptides
Sub ClassAmino acids
Pubchem CID5810
Annotation level1   (1:Known structure; 2:Known regiochemistry; 3:Partial structure; 4:Sum-composition)
Human quantitationView measurements in targeted assays on human samples

Table of KEGG reactions in human pathways involving trans-4-Hydroxyproline

Rxn IDKEGG ReactionEnzyme
R03293 Hydroxyproline + NADP+ <=> L-1-Pyrroline-3-hydroxy-5-carboxylate + NADPH + H+trans-4-Hydroxy-L-proline:NADP+ 5-oxidoreductase
R01252 L-Proline + 2-Oxoglutarate + Oxygen <=> Hydroxyproline + Succinate + CO2L-Proline,2-oxoglutarate:oxygen oxidoreductase (4-hydroxylating)
R03291 Hydroxyproline + NAD+ <=> L-1-Pyrroline-3-hydroxy-5-carboxylate + NADH + H+trans-4-Hydroxy-L-proline:NAD+ 5-oxidoreductase
R03295 Hydroxyproline + Quinone <=> L-1-Pyrroline-3-hydroxy-5-carboxylate + Hydroquinonetrans-4-hydroxy-L-proline:quinone oxidoreductase

Table of KEGG human pathways containing trans-4-Hydroxyproline

Pathway IDHuman Pathway# of reactions
hsa00330 Arginine and proline metabolism 2