Summary of Study ST002343
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001502. The data can be accessed directly via it's Project DOI: 10.21228/M8JD81 This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.
| Study ID | ST002343 |
| Study Title | The impact of myriocin and dietary serine restriction on paw skin sphingolipid diversity |
| Study Summary | We analyzed paw skin polar and lipid metabolites in mice (C57BL/6J) in response to two dietary interventions. The first was: 1) low fat (LFD), 2) serine/glycine-free LFD (-SG LFD), high fat (HFD), and serine/glycine-free HFD (-SG HFD). And the second was: 1) low fat (LFD), high fat (HFD), serine/glycine-free HFD (-SG HFD), and serine/glycine-free HFD (-SG HFD) with myriocin (0.3 mg/kg every other day) treatment. The goal of the study was to determine the impact of dietary serine/glycine restriction and myriocin treatment on the hepatic lipidome. |
| Institute | Salk Institute for Biological Studies |
| Department | Molecular and Cell Biology Laboratory |
| Laboratory | Metallo Lab |
| Last Name | Handzlik |
| First Name | Michal |
| Address | 10010 N Torrey Pines Rd, La Jolla, California, 92037, USA |
| mhandzlik@salk.edu | |
| Phone | 2069601945 |
| Submit Date | 2022-11-11 |
| Num Groups | LFD, -SG LFD, HFD, -SG HFD, LFD+Veh, HFD+Veh, -SG HFD+Veh, -SG HFD+Myr |
| Total Subjects | 47 |
| Num Males | 47 |
| Raw Data Available | Yes |
| Raw Data File Type(s) | d |
| Analysis Type Detail | LC-MS |
| Release Date | 2024-01-01 |
| Release Version | 1 |
Select appropriate tab below to view additional metadata details:
Factors:
Subject type: Mammal; Subject species: Mus musculus (Factor headings shown in green)
| mb_sample_id | local_sample_id | Group |
|---|---|---|
| SA235234 | 317 | High fat diet + vehicle |
| SA235235 | 316 | High fat diet + vehicle |
| SA235236 | 314 | High fat diet + vehicle |
| SA235237 | 318 | High fat diet + vehicle |
| SA235238 | 315 | High fat diet + vehicle |
| SA235239 | 320 | High fat diet + vehicle |
| SA235240 | 323 | High fat diet + vehicle |
| SA235241 | 322 | High fat diet + vehicle |
| SA235242 | 321 | High fat diet + vehicle |
| SA235243 | 313 | High fat diet + vehicle |
| SA235244 | 319 | High fat diet + vehicle |
| SA235245 | 324 | High fat diet + vehicle |
| SA235246 | 304 | Low fat diet + vehicle |
| SA235247 | 305 | Low fat diet + vehicle |
| SA235248 | 303 | Low fat diet + vehicle |
| SA235249 | 301 | Low fat diet + vehicle |
| SA235250 | 312 | Low fat diet + vehicle |
| SA235251 | 306 | Low fat diet + vehicle |
| SA235252 | 302 | Low fat diet + vehicle |
| SA235253 | 311 | Low fat diet + vehicle |
| SA235254 | 307 | Low fat diet + vehicle |
| SA235255 | 310 | Low fat diet + vehicle |
| SA235256 | 309 | Low fat diet + vehicle |
| SA235257 | 308 | Low fat diet + vehicle |
| SA235258 | 342 | Serine/glycine-free high fat diet + myriocin |
| SA235259 | 343 | Serine/glycine-free high fat diet + myriocin |
| SA235260 | 338 | Serine/glycine-free high fat diet + myriocin |
| SA235261 | 340 | Serine/glycine-free high fat diet + myriocin |
| SA235262 | 341 | Serine/glycine-free high fat diet + myriocin |
| SA235263 | 346 | Serine/glycine-free high fat diet + myriocin |
| SA235264 | 337 | Serine/glycine-free high fat diet + myriocin |
| SA235265 | 348 | Serine/glycine-free high fat diet + myriocin |
| SA235266 | 347 | Serine/glycine-free high fat diet + myriocin |
| SA235267 | 345 | Serine/glycine-free high fat diet + myriocin |
| SA235268 | 344 | Serine/glycine-free high fat diet + myriocin |
| SA235269 | 331 | Serine/glycine-free high fat diet + vehicle |
| SA235270 | 328 | Serine/glycine-free high fat diet + vehicle |
| SA235271 | 327 | Serine/glycine-free high fat diet + vehicle |
| SA235272 | 326 | Serine/glycine-free high fat diet + vehicle |
| SA235273 | 325 | Serine/glycine-free high fat diet + vehicle |
| SA235274 | 329 | Serine/glycine-free high fat diet + vehicle |
| SA235275 | 330 | Serine/glycine-free high fat diet + vehicle |
| SA235276 | 335 | Serine/glycine-free high fat diet + vehicle |
| SA235277 | 334 | Serine/glycine-free high fat diet + vehicle |
| SA235278 | 333 | Serine/glycine-free high fat diet + vehicle |
| SA235279 | 332 | Serine/glycine-free high fat diet + vehicle |
| SA235280 | 336 | Serine/glycine-free high fat diet + vehicle |
| Showing results 1 to 47 of 47 |
