Summary of Study ST002368
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001499. The data can be accessed directly via it's Project DOI: 10.21228/M8ZM62 This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.
Study ID | ST002368 |
Study Title | Sperm Environmental Epigenetics and Development Study (SEEDS) |
Study Summary | Infertility is one of the most common reproductive health disorders affecting 16% of couples in the U.S. Most concerning are the new meta-analysis data showing that sperm counts among men in developed countries have declined over 50% in the past four decades. With no sign of reversing this downward trajectory, we may not only be facing a fertility crisis, but low sperm count also has wider public health implications, including increased risks in morbidity and mortality. Given this dramatic decrease in sperm quality over a short period, genetic influences are likely not attributable, but rather, environmental factors encountered over the life-course. The objective of this pilot project is to determine the feasibility of generating metabolomic data from human seminal plasma collected as part of the ongoing SEEDS cohort. |
Institute | Wayne State University |
Last Name | Pilsner |
First Name | Rick |
Address | 275 E. Hancock Street, Detroit, MI, USA |
rpilsner@wayne.edu | |
Phone | 917-557-2499 |
Submit Date | 2022-11-17 |
Total Subjects | 10 |
Raw Data Available | Yes |
Raw Data File Type(s) | raw(Thermo) |
Analysis Type Detail | LC-MS |
Release Date | 2023-05-12 |
Release Version | 1 |
Select appropriate tab below to view additional metadata details:
Combined analysis:
Analysis ID | AN003863 |
---|---|
Analysis type | MS |
Chromatography type | Reversed phase |
Chromatography system | Thermo Scientific™ Vanquish™ UPHPLC |
Column | Acquity UPLC HSS T3 C18 (100 x 2.1mm, 1.8um) |
MS Type | ESI |
MS instrument type | Orbitrap |
MS instrument name | Thermo Q Exactive HF-X Orbitrap |
Ion Mode | POSITIVE |
Units | Intensity |
MS:
MS ID: | MS003604 |
Analysis ID: | AN003863 |
Instrument Name: | Thermo Q Exactive HF-X Orbitrap |
Instrument Type: | Orbitrap |
MS Type: | ESI |
MS Comments: | Instrument: Thermo Q Exactive HFx Software: Xcalibur 4.1.31.9 for data acquisition; Progenesis QI 2.4 for data preprocessing |
Ion Mode: | POSITIVE |
Capillary Temperature: | 320 °C |
Capillary Voltage: | 3.5 KV |
Collision Energy: | 20-45, ramp |
Collision Gas: | N2 |
Dry Gas Flow: | 55 |
Dry Gas Temp: | 400°C |
Fragmentation Method: | CID |
Desolvation Gas Flow: | 55 |