Summary of Study ST002368
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001499. The data can be accessed directly via it's Project DOI: 10.21228/M8ZM62 This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.
| Study ID | ST002368 |
| Study Title | Sperm Environmental Epigenetics and Development Study (SEEDS) |
| Study Summary | Infertility is one of the most common reproductive health disorders affecting 16% of couples in the U.S. Most concerning are the new meta-analysis data showing that sperm counts among men in developed countries have declined over 50% in the past four decades. With no sign of reversing this downward trajectory, we may not only be facing a fertility crisis, but low sperm count also has wider public health implications, including increased risks in morbidity and mortality. Given this dramatic decrease in sperm quality over a short period, genetic influences are likely not attributable, but rather, environmental factors encountered over the life-course. The objective of this pilot project is to determine the feasibility of generating metabolomic data from human seminal plasma collected as part of the ongoing SEEDS cohort. |
| Institute | Wayne State University |
| Last Name | Pilsner |
| First Name | Rick |
| Address | 275 E. Hancock Street, Detroit, MI, USA |
| rpilsner@wayne.edu | |
| Phone | 917-557-2499 |
| Submit Date | 2022-11-17 |
| Total Subjects | 10 |
| Raw Data Available | Yes |
| Raw Data File Type(s) | raw(Thermo) |
| Analysis Type Detail | LC-MS |
| Release Date | 2023-05-12 |
| Release Version | 1 |
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Collection:
| Collection ID: | CO002450 |
| Collection Summary: | Semen samples were collected in a sterile plastic specimen cup after a 2–3-day abstinence period. To separate motile sperm from the seminal plasma, semen samples were processed using a two-step (80 and 40%) gradient fractionation. The seminal plasma was removed from the top of the gradient and placed in a sterile tube and frozen at -80oC until analyses. |
| Sample Type: | Seminal plasma |
| Storage Conditions: | -80℃ |
