Summary of Study ST000948
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000652. The data can be accessed directly via it's Project DOI: 10.21228/M8D38P This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
Study ID | ST000948 |
Study Title | Mechanisms for Insulin Resistance in Polycystic Ovary Syndrome: aminoadipic acid, lysine concentrations, and enrichment (part II) |
Study Summary | To determine how metformin therapy changes lysine and AAA kinetics in PCOS and whether this is associated with improvements in insulin sensitivity. Changes in lysine and AAA flux before and after three months of metformin therapy will be compared to women with PCOS randomized to no treatment for three months. |
Institute | Mayo Clinic |
Last Name | Chang |
First Name | Alice |
Address | 200 First St. SW, Rochester, Minnesota, 55905, USA |
Chang.Alice1@mayo.edu | |
Phone | 507-286-0505 |
Submit Date | 2018-04-09 |
Analysis Type Detail | LC-MS |
Release Date | 2020-04-13 |
Release Version | 1 |
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Sample Preparation:
Sampleprep ID: | SP000994 |
Sampleprep Summary: | Plasma lysine and AAA concentrations and isotopic enrichment will be analyzed as previous described via a Thermo Fisher Q Exactive plus mass spectrometer coupled with a Dionex UltiMate 3000 Binary RSLC liquid chromatograph. |