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MB Sample ID: SA033032

Local Sample ID:2190002
Subject ID:SU000622
Subject Type:Animal
Subject Species:Macaca mulatta
Taxonomy ID:9544
Weight Or Weight Range:NA|6.94kg|9.04kg|8.03kg|8.83kg|8.68kg
Gender:Male|Male|Male|Male|Male|Male
Animal Animal Supplier:Yerkes Field Station|Yerkes Field Station|Yerkes Primate Research Center|Yerkes Primate Research Center||Yerkes Primate Research Center
Animal Housing:Metallic|Metallic|Metallic|Metallic|Metallic|Metallic
Animal Light Cycle:12/12|12/12|12/12|12/12|12/12|12/12
Animal Feed:Monkey Jumbo Diet 5037 and 5038|Monkey Jumbo Diet 5037 and 5038|Monkey Jumbo Diet 5037 and 5038|Monkey Jumbo Diet 5037 and 5038|Monkey Jumbo Diet 5037 and 5038|Monkey Jumbo Diet 5037 and 5038
Animal Water:tap in bottle|tap in bottle|tap in bottle|tap in bottle|tap in bottle|tap in bottle
Animal Inclusion Criteria:Weight|Weight|Weight|Weight|Weight|Weight
Species Group:Mammal

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Collection:

Collection ID:CO000616
Collection Summary:Every Other Day Collection | Time Point 1 Baseline: Uninfected control for each Non-Human Primate (NHP). | Time Point 2 Peak of infection: Peak of infection determined by clinical and parasitological assessment for each NHP. The time point is intended to characterize the host immune response and capture multi-omics data during the peak of parasitemias when the NHP is experiencing clinical signs of disease that are commonly severe in P. coatneyi infections. NHPs were monitored based on clinical and hematological parameters, and clinical interventions with artemether were performed as necessary. | Time Point 3 Post-peak: Observations 7 days after peak infection and sub-curative treatment. | Time Point 4 Recrudescence Peak: This time point tested expectations of a drop in hemoglobin levels and increase in parasitemias due to recrudescence from a chronic infection. After sample collection, NHPs received sub-curative treatment with artemether based on clinical and hematological parameters. | Time Point 5 Post-peak: Chronic infection with low levels of persistent parasitemia that may be below detectable levels. | Time Point 6 Recrudescence Peak: Same goal as time point 4 for 2nd second recrudescence peak. | Time Point 7 Post-peak: Observations of NHP response after a second recrudescence in a chronic phase with low levels of persistent parasitemia.
Sample Type:Whole blood|Whole blood|Whole blood|Whole blood|Whole blood|Whole blood|Whole blood|Whole blood
Collection Method:Ear Prick|Intravenous|Intravenous|Intravenous|Intravenous|Intravenous|Intravenous|Intravenous
Collection Frequency:Every Other Day|Once|Once|Once|Once|Once|Once|Once
Blood Serum Or Plasma:Plasma|Plasma|Plasma|Plasma|Plasma|Plasma|Plasma|Plasma
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