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MB Sample ID: SA199914
| Local Sample ID: | 13429J |
| Subject ID: | SU002173 |
| Subject Type: | Human |
| Subject Species: | Homo sapiens |
| Taxonomy ID: | 9606 |
| Age Or Age Range: | 40-80 |
| Gender: | Male and female |
| Human Race: | Non-hispanic White and African-American |
| Human Smoking Status: | Current/Former/Never |
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Collection:
| Collection ID: | CO002166 |
| Collection Summary: | The NIH sponsored multicenter Genetic Epidemiology of COPD (COPDGene (ClinicalTrials.gov Identifier: NCT01969344) study was approved and reviewed by the institutional review board at all participating centers (1). All study participants provided written informed consent. This study enrolled 10,198 non-Hispanic white (NHW) and African American (AA) individuals from January 2008 until April 2011 (Phase 1) who were aged 45-80 with ≥10 pack-year smoking history and no exacerbations for >30 days. In addition, 465 age and gender matched healthy individuals with no history of smoking were enrolled as controls (mostly at Phase 2). From July 2013 to July 2017, 5,697 subjects returned for an in-person 5-year visit. Each in-person visit included spirometry before and after albuterol, quantitative CT imaging of the chest, and blood sampling. From two clinical centers (National Jewish Health and University of Iowa) 1,136 subjects (1,040 NHW, 96 AA) participated in an ancillary study in which they provided fresh frozen plasma collected using an 8.5 ml p100 tube (Becton Dickinson) at Phase 2. Subject data includes: gender(Male/Female); race.eth (Non-Hispanic, White/Black African American/Other); smoking_status (Never smoked/Former Smoker/Current Smoker); ccenter (Clinical center); FEV1_post.2 (Post-bronchodilator, FEV1); adj_density_mesa (MESA-adjusted lung density), age_visit (Age years); BMI (Body Mass Index); ATS_PackYears (pack-years of smoking) |
| Sample Type: | Blood (plasma) |
