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MB Sample ID: SA241632

Local Sample ID:1561
Subject ID:SU002500
Subject Type:Human
Subject Species:Homo sapiens
Taxonomy ID:9606

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Collection:

Collection ID:CO002493
Collection Summary:Fifteen healthy subjects were enrolled in this study, and each swallowed at least 17 devices over the course of three days. Sample size was chosen to assess general variation across human intestinal tracts. Daily instructions included the following guidelines: record all foods and time they were consumed throughout the day; if you work out, do so in the morning; eat breakfast and lunch as usual; swallow a set of four devices three hours after lunch with up to 2/3 cup water; do not eat or drink anything for at least two hours after swallowing devices; if hungry after two hours, snack lightly (up to 200 calories); do not drink any caffeinated beverages after lunch until the next morning; collect all stool starting six hours after swallowing this set of devices until 48 hours after swallowing the next set of devices; eat dinner as usual at least six hours after lunch; swallow a set of four CapScan devices three hours after dinner with 2/3 cup water; after swallowing this set, do not eat or drink anything until the morning. Alcohol consumption and diet contents were not restricted. All ingested devices were recovered, and no adverse events were reported during the study. In total 274 capsule devices provided sufficient material for metabolomics analysis, and 225 provided sufficient volume or number of sequencing reads (>2500) for genomic analysis. Every bowel movement during the study was immediately frozen by the subject at -20 °C. Subject 1 provided additional samples for assessment of replicability and blooming. A total of 333 intestinal, and stool samples were analyzed with metabolomics methods.
Sample Type:Intestine
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