Return to study ST001205 main page
MB Sample ID: SA084758
| Local Sample ID: | 1h_DHA_S_troph_d |
| Subject ID: | SU001272 |
| Subject Type: | Cultured cells |
| Subject Species: | Plasmodium falciparum;Homo sapiens |
| Taxonomy ID: | 5833;9606 |
| Genotype Strain: | Cam3.IIR539T and Cam3.IIrev |
| Age Or Age Range: | 22-26 h post invasion |
Select appropriate tab below to view additional metadata details:
Treatment:
| Treatment ID: | TR001287 |
| Treatment Summary: | RBCs infected with Cam3.IIR539T (resistant) or Cam3.IIrev (sensitive) P. falciparum parasites (22-26 h post invasion) at 4% parasitaemia and 2% Hct were treated with 100 nM of DHA, OZ277 or OZ439 (or an equivalent volume of DMSO) for 1, 3 and 5 h, respectively. During the drug incubation period parasite cultures were at 37°C under a gas atmosphere of 94% N2, 5% CO2 and 1% O2. |
| Treatment Compound: | OZ277 (arterolane), OZ439 (artefenomel) and dihydroartemisinin (DHA) |
| Treatment Vehicle: | DMSO |
| Cell Media: | Complete RPMI medium (10.4 g/L) containing HEPES (5.94 g/L), hypoxanthine (50 mg/L), sodium bicarbonate (2.1 g/L) and Albumax II (5 g/L). |
| Cell Media Lastchanged: | Immediately prior to initiation of drug incubation |
