Metabolomics Workbench : NIH Data Repository

MB Sample ID: SA095973

Local Sample ID:	S3D
Subject ID:	SU001397
Subject Type:	Mammal
Subject Species:	Mus musculus
Taxonomy ID:	10090
Genotype Strain:	C57BL/6

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Chromatography
Analysis
MS

Treatment:

Treatment ID:	TR001412
Treatment Summary:	C57BL/6 mice (n=44) were divided into 4 groups (n=11 per group) and fed High-fat diet (HFD), 1% deoxycholic acid (DCA) in drinking water, both, or left as control for 9 months. Serum samples were collected and analyzed by targeted lipidomics as described in Supplemental Information. The two treatments were selected to demonstrate the ability of lipidomics to detect gross changes induced by HFD in the serum lipidome, as well as specific/minor changes induced by the secondary bile acid (DCA) through regulation of liver lipid metabolism.

Treatment ID:

TR001412

Treatment Summary:

C57BL/6 mice (n=44) were divided into 4 groups (n=11 per group) and fed High-fat diet (HFD), 1% deoxycholic acid (DCA) in drinking water, both, or left as control for 9 months. Serum samples were collected and analyzed by targeted lipidomics as described in Supplemental Information. The two treatments were selected to demonstrate the ability of lipidomics to detect gross changes induced by HFD in the serum lipidome, as well as specific/minor changes induced by the secondary bile acid (DCA) through regulation of liver lipid metabolism.