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MB Sample ID: SA183903

Local Sample ID:21_021
Subject ID:SU002027
Subject Type:Human
Subject Species:Homo sapiens
Taxonomy ID:9606
Age Or Age Range:21 - 84
Gender:Male and female

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Treatment:

Treatment ID:TR002039
Treatment Summary:Biobanked plasma samples were acquired from a subset of RA patients (n=20) that participated in a 16-week multicenter open-label study that sought to evaluated predictors of MTX response in RA (ClinicalTrials.gov NCT03414502) (PMID: 32911284). The study included sites within the Rheumatology Arthritis Investigational Network (RAIN). For each patient, plasma samples at baseline and 16-weeks were provided for analysis. All patients received 15 mg/week of MTX and 1 mg/day of folic acid upon enrollment. The MTX does was escalated to 20 mg/week in patients that did not achieve clinical remission by 8 weeks, as tolerated.
Treatment Compound:Methotrexate
Treatment Route:Subcutaneous or Oral
Treatment Dose:15-20 mg/week
Treatment Doseduration:16 weeks
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