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MB Sample ID: SA232341

Local Sample ID:	tumor # 48
Subject ID:	SU002424
Subject Type:	Mammal
Subject Species:	Mus musculus
Taxonomy ID:	10090

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Treatment:

Treatment ID:	TR002436
Treatment Summary:	Human melanoma xenografts were established in mice using A375 and WM47 (BRAF mutant), WM3311 (BRAF/NRAS wild-type) and WM3000 (NRAS mutant) cells. Once the tumor volume reached 100 mm3, mice were equally assigned to control diet (CTRL) and two ketogenic diet (KDs) differing in their fat composition (LCT: long-chain triglyceride-based KD and LCT-MCT: long-chain triglyceride-based KD supplemented with C8 and C10 medium-chain triglycerides, ratio of fat to the sum of carbohydrate and protein of 8:1). Both KDs were administered ad libitum as monotherapy.

Treatment ID:

TR002436

Treatment Summary:

Human melanoma xenografts were established in mice using A375 and WM47 (BRAF mutant), WM3311 (BRAF/NRAS wild-type) and WM3000 (NRAS mutant) cells. Once the tumor volume reached 100 mm3, mice were equally assigned to control diet (CTRL) and two ketogenic diet (KDs) differing in their fat composition (LCT: long-chain triglyceride-based KD and LCT-MCT: long-chain triglyceride-based KD supplemented with C8 and C10 medium-chain triglycerides, ratio of fat to the sum of carbohydrate and protein of 8:1). Both KDs were administered ad libitum as monotherapy.