Metabolomics Workbench : NIH Data Repository

MB Sample ID: SA236517

Local Sample ID:	EicoP13
Subject ID:	SU002443
Subject Type:	Mammal
Subject Species:	Rattus norvegicus
Taxonomy ID:	10116
Age Or Age Range:	26 weeks of age
Weight Or Weight Range:	320-460 grams
Gender:	Male
Animal Animal Supplier:	RRRC (University of Missouri)
Animal Housing:	Center for Comparative Medicine UConn
Animal Feed:	Modified AIN-93G diet from Research Diets
Animal Water:	ab libitum

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Treatment:

Treatment ID:	TR002455
Treatment Summary:	Rats were fed two doses of TP-252 equivalent to consuming 1.3 and 2.6 g/kg/day for LD TP-252 and HD TP-252, respectively. Alternatively, rats were also fed a diet containing 2% EPA-FFA in their diet (equivalent to 1.14 g/kg/day of EPA). In groups receiving naproxen, the dose of naproxen was 11.4 mg/kg/day, or roughly 4 mg/rat/day. These treatment groups were carried out for the 20 weeks, and then animals were sacrificed and tissue collected and analyzed.

Treatment ID:

TR002455

Treatment Summary:

Rats were fed two doses of TP-252 equivalent to consuming 1.3 and 2.6 g/kg/day for LD TP-252 and HD TP-252, respectively. Alternatively, rats were also fed a diet containing 2% EPA-FFA in their diet (equivalent to 1.14 g/kg/day of EPA). In groups receiving naproxen, the dose of naproxen was 11.4 mg/kg/day, or roughly 4 mg/rat/day. These treatment groups were carried out for the 20 weeks, and then animals were sacrificed and tissue collected and analyzed.