Summary of Study ST001408

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000964. The data can be accessed directly via it's Project DOI: 10.21228/M83406 This work is supported by NIH grant, U2C- DK119886.

See: https://www.metabolomicsworkbench.org/about/howtocite.php

This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.

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Study IDST001408
Study TitleMetabolomic profiling of baseline plasmas from a longitudinal prospective cohort of 491 active surveillance (AS) participants
Study TypeBiomarker study
Study SummaryUntargeted metabolomics analyses were performed on clinically matched baseline plasma samples (n = 16 per group) prospectively collected from patients with clinically low-risk early stage prostate cancer undergoing AS who exhibited early disease progression (DP) (defined as upgrading of Gleason score (GS) and/or increased tumor volume on surveillance biopsy within 18 months after start of AS) or indolent disease (no progression for five or more years after start of AS) as well as 459 baseline plasma samples prospectively collected from patients with early-stage prostate cancer undergoing AS.
Institute
University of Texas MD Anderson Cancer Center
DepartmentDepartment of Clinical Cancer Prevention
Last NameVykoukal
First NameJody
Address6767 Bertner Ave, Houston, TX 77030
Emailjvykouka@mdanderson.org
Phone713-834-6095
Submit Date2020-05-19
Raw Data AvailableYes
Analysis Type DetailLC-MS
Release Date2020-07-02
Release Version1
Jody Vykoukal Jody Vykoukal
https://dx.doi.org/10.21228/M83406
ftp://www.metabolomicsworkbench.org/Studies/ application/zip

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Combined analysis:

Analysis ID AN002352 AN002353 AN002354
Analysis type MS MS MS
Chromatography type HILIC Reversed phase Reversed phase
Chromatography system Waters Acquity UPLC Waters Acquity UPLC Waters Acquity UPLC
Column Waters Acquity UPLC BEH amide,(100 x 2.1mm,1.7um,100 Å) Waters ACQUITY UPLC HSS T3 (100 x 2.1mm,1.8um,100 Å) Waters ACQUITY UPLC HSS T3 (100 x 2.1mm,1.8um,100 Å)
MS Type ESI ESI ESI
MS instrument type QTOF QTOF QTOF
MS instrument name Waters Xevo G2-XS Waters Xevo G2-XS Waters Xevo G2-XS
Ion Mode POSITIVE POSITIVE POSITIVE
Units normalized ion abundance normalized ion abundance normalized ion abundance
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