Summary of Study ST001136

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench,, where it has been assigned Project ID PR000760. The data can be accessed directly via it's Project DOI: 10.21228/M8FH6C This work is supported by NIH grant, U2C- DK119886.


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Study IDST001136
Study TitleMetabolme analysis of OPC-163493 on the Liver of ZDF rats (part-II)
Study TypeLong-term in vivo test
Study SummaryMetabolome analysis were on the 24 samples of ZDF rats that were treated with OPC-163493 for 6-weeks. The 24 samples were composed of 3 different groups (Vehicles, OPC-163493 treatment, and baseline control; each n=8).
Otsuka Pharmaceutical Co., Ltd.
Last NameKanemoto
First NameNaohide
Address463-10 Kagasuno Kawauchi-cho Tokushima 771-0192, Japan
Submit Date2019-02-07
Analysis Type DetailLC-MS
Release Date2019-03-06
Release Version1
Naohide Kanemoto Naohide Kanemoto application/zip

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Combined analysis:

Analysis ID AN001862 AN001863
Analysis type MS MS
Chromatography type CE CE
Chromatography system Agilent 7100 CE Agilent 7100 CE
Column Fused silica capillary, i.d. 50 μm × 80 cm Fused silica capillary, i.d. 50 μm × 80 cm
MS instrument type Other Triple quadrupole
MS instrument name Agilent 6210 TOF Agilent 6460 QQQ
Units Concentration (nmol/g tissue) Concentration (nmol/g tissue)


Chromatography ID:CH001348
Chromatography Summary:capillary electrophoresis was connected with time-of-flight mass spectrometry (CE-TOFMS) for cation analysis and tandem mass spectrometry (CE-MS/MS) for anion.
Instrument Name:Agilent 7100 CE
Column Name:Fused silica capillary, i.d. 50 μm × 80 cm
Chromatography Type:CE