Summary of Study ST001420

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench,, where it has been assigned Project ID PR000974. The data can be accessed directly via it's Project DOI: 10.21228/M8SQ55 This work is supported by NIH grant, U2C- DK119886.


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Study IDST001420
Study TitleMetabolomic analysis of patients with recurrent angina
Study TypeCase and control studies
Study SummaryThis is a prospective study. After an overnight fast, venous blood was collected from patients with PCI. The patients were discharged after the blood draw. They were followed up every 30 days for angina recurrence up to 270 days (9 months). The samples were grouped into two groups: recurrent angina and angina-free based on the follow-up results at 9 months.
University of California, San Diego
Last NameCui
First NameSong
Address9500 Gilman Drive, San Diego, CA, 92093, USA
Submit Date2020-06-30
Num Groups2
Total Subjects750
Num Males365
Num Females385
Release Date2020-07-30
Release Version1
Song Cui Song Cui application/zip

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Combined analysis:

Analysis ID AN002375
Analysis type MS
Chromatography type HILIC
Chromatography system Shimadzu 20AD
Column Shodex ODP2 HP-4B 5um polymer (50 x 4.6mm)
MS instrument type Triple quadrupole
MS instrument name ABI Sciex 6500 QTrap
Units Peak area


Chromatography ID:CH001743
Chromatography Summary:Metabolomic analysis was performed on a Shimadzu LC-20A ultra-high-performance liquid chromatography coupled with SCIEX QTRAP 6500+ triple quadrupole mass spectrometer (LC-MS/MS) using a broad-spectrum targeted metabolomic approach. Ten µL of the extract was injected into a 250 mm × 2.0 mm, 4 µm polymer-based NH2 HPLC column (Asahipak NH2P-40 2E, Showa Denko America, Inc., NY) held at 25°C for chromatographic separation. The mobile phase was solvent A: 95% water, 5% acetonitrile with 20 mM NH4OAC, and 20 mM NH4OH (pH 9.4); solvent B: 100% acetonitrile. Separation was achieved using the following gradient: 0-3.5 min: 95% B, 3.6-8 min: 85% B, 8.1-13 min: 75% B, 14-30 min: 0% B, 31-41 min: 95% B, 41.1 min: end. The flow rate was 250 µL/min.
Instrument Name:Shimadzu 20AD
Column Name:Shodex ODP2 HP-4B 5um polymer (50 x 4.6mm)
Column Temperature:25 ℃
Flow Gradient:0-3.5 min: 95% B, 3.6-8 min: 85% B, 8.1-13 min: 75% B, 14-30 min: 0% B, 31-41 min: 95% B, 41.1 min: end.
Flow Rate:250 µL/min
Solvent A:95% water/5% acetonitrile; 20 mM ammonium hydroxide, pH 9.4 (adjusted by formic acid)
Solvent B:100% acetonitrile
Chromatography Type:HILIC