Summary of Study ST002123
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001347. The data can be accessed directly via it's Project DOI: 10.21228/M8M417 This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.
Study ID | ST002123 |
Study Title | GCN2 regulates mitochondrial OXPHOS in HSPCs under proliferation conditions. |
Study Summary | Our results revealed that among all 273 metabolites detected, the levels of metabolites involved in glucose-related glycolysis and gluconeogenesis were elevated in GCN2 deleted HSPCs. Moreover, GCN2 deletion specifically increased mitochondrial OXPHOS and suppressed anaerobic glycolysis in HSPCs. |
Institute | Sun Yat-sen University |
Last Name | Zhao |
First Name | Meng |
Address | Zhongshan 2nd Road |
zhaom38@mail.sysu.edu.cn | |
Phone | 18138799889 |
Submit Date | 2022-04-05 |
Raw Data Available | Yes |
Raw Data File Type(s) | wiff |
Analysis Type Detail | LC-MS |
Release Date | 2022-11-01 |
Release Version | 1 |
Select appropriate tab below to view additional metadata details:
Combined analysis:
Analysis ID | AN003476 |
---|---|
Analysis type | MS |
Chromatography type | HILIC |
Chromatography system | ACQUITY UPLC |
Column | Waters ACQUITY UPLC BEH Amide |
MS Type | ESI |
MS instrument type | Triple quadrupole |
MS instrument name | ABI Sciex 5500 QTrap |
Ion Mode | UNSPECIFIED |
Units | AU |
Chromatography:
Chromatography ID: | CH002565 |
Instrument Name: | ACQUITY UPLC |
Column Name: | Waters ACQUITY UPLC BEH Amide |
Column Temperature: | 40 |
Flow Gradient: | The gradient program started at 85% (B) and was reduced to 70% (B) over 9 min, then reduced from 70% (B) to 30% (B) over 3 min, followed by wash with 30% (B) for another 3 min, and finally 5 min re-equilibration with 85% (B). |
Flow Rate: | 0.35ml/min |
Solvent A: | 100% water; 10mM ammonium formate |
Solvent B: | 100% acetonitrile |
Chromatography Type: | HILIC |