Summary of Study ST002468
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001594. The data can be accessed directly via it's Project DOI: 10.21228/M8NQ69 This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.
| Study ID | ST002468 |
| Study Title | First approach on the use of samples from fecal occult blood screening kits for metabolomic analysis. Application in colorectal cancer population. |
| Study Summary | Cancer is the most common disease around the world and colorectal cancer is the second most common cancer. The early diagnosis of colorectal cancer is difficult and relies on invasive diag-nostic tools such as colonoscopy and tissue biopsy. Other non-invasive techniques such as fecal occult blood screening test (FOBT) are less sensitive and accurate. The advantage of FOBT together with high throughput technology such as metabolomics could provide the advantages of non-invasive tool and the effectiveness of detecting novel colorectal cancer markers. In this way, this work focuses on the novelty of using FOBT as samples to perform metabolomics analysis and its application on colorectal cancer population. |
| Institute | CIC bioGUNE - Centro de Investigación Cooperativa en Biociencias |
| Last Name | Alboniga |
| First Name | Oihane |
| Address | Bizkaia Technology Park, Bld.800, Derio, Bizkaia, 48160, Spain |
| oalboniga@cicbiogun.es | |
| Phone | +34 944061317 |
| Submit Date | 2022-12-09 |
| Raw Data Available | Yes |
| Raw Data File Type(s) | mzML |
| Analysis Type Detail | LC-MS |
| Release Date | 2023-02-22 |
| Release Version | 1 |
Select appropriate tab below to view additional metadata details:
Combined analysis:
| Analysis ID | AN004024 |
|---|---|
| Analysis type | MS |
| Chromatography type | Reversed phase |
| Chromatography system | Waters Acquity |
| Column | Waters Acquity UPLC BEH C18 (100 x 1.0 mm, 1.7um) |
| MS Type | ESI |
| MS instrument type | QTOF |
| MS instrument name | Waters QTOF Premier |
| Ion Mode | POSITIVE |
| Units | normalized peak area |
Chromatography:
| Chromatography ID: | CH002974 |
| Instrument Name: | Waters Acquity |
| Column Name: | Waters Acquity UPLC BEH C18 (100 x 1.0 mm, 1.7um) |
| Column Temperature: | - |
| Flow Gradient: | A 10 minutes linear gradient increasing from 40% to 100% of B was used. After 5 minutes at 100% B, the mobile phase was reset to the initial conditions and maintained for 2 minutes. Total run 17 minutes. |
| Flow Rate: | 0.15 mL/min |
| Solvent A: | 40% water/60% acetonitrile; 10mM ammonium formate |
| Solvent B: | 25% acetonitrile/75% isopropanol; 10mM ammonium formate |
| Chromatography Type: | Reversed phase |
