Summary of Study ST000613
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000448. The data can be accessed directly via it's Project DOI: 10.21228/M84W37 This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
| Study ID | ST000613 |
| Study Title | Human TM Sphingolipid Analysis (part II) |
| Study Summary | We determined the profiles of sphingomyelin, sphingoid base, sphingoid base-1-phosphate, and ceramide, and their quantitative differences between control and glaucomatous trabecular meshwork (TM) derived from human donors. |
| Institute | University of Miami |
| Last Name | Bhattacharya |
| First Name | Sanjoy |
| Address | McKnight Vision Research Building, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, 1638 NW 10th Avenue, Room 706A, Miami, Florida 33136 |
| Sbhattacharya@med.miami.edu | |
| Phone | 305-482-4103 |
| Submit Date | 2017-05-26 |
| Raw Data Available | Yes |
| Raw Data File Type(s) | raw(Thermo) |
| Analysis Type Detail | MS(Dir. Inf.) |
| Release Date | 2019-07-17 |
| Release Version | 1 |
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Collection:
| Collection ID: | CO000630 |
| Collection Summary: | The POAG and control TM were procured from cadaver donor eyes or as a surgical specimen(POAG) following institutional review board approved protocols and adherence to the tenets of the Declaration of Helsinki. The TM specimens, during transit, were stored in Optisol(Bausch & Lomb, Rochester, NY, USA) at 48C followed by storage in _808C until time of use. The donors of both sexes, and with a mean age of 56.3+/- 12.7 years for control and 70.1 +/- 11.04 years for glaucoma, were used for these studies. Tissues were sourced from Midwest Eye-Banks, Lions Eye Bank (Miami, FL, USA) and Mundorf Eye Institute (Charlotte, NC, USA). The TM tissue was isolated using published procedures. |
| Sample Type: | Eye tissue |
