Summary of Study ST001931

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench,, where it has been assigned Project ID PR001220. The data can be accessed directly via it's Project DOI: 10.21228/M81129 This work is supported by NIH grant, U2C- DK119886.


This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.

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Study IDST001931
Study TitlePesticides, Perfluorinated compounds and the development of adolescents in agricultural communities
Study SummaryThis project aims to evaluate the developmental effects of pesticides and perfluroalkyl and polyfluroralkyl substances (PFAS) in adolescent participants of the study of Secondary Pesticide Exposure on Children and Adolescents (ESPINA) living in floricultural communities in Pedro Moncayo County, Ecuador. This prospective cohort study of children examines pesticide and PFAS exposures and the association with neurobehavioral performance, including anxiety and depression, and endocrine changes in adrenal and sex hormones in children aged 12 to 17 years. Analysis of adolescent serum metabolome changes aim to characterize metabolic and biological effects and their association to neuro behavioral outcomes and hormonal changes related to the developmental effects of PFAS from agricultural sources.
Emory University
DepartmentSchool of Medicine
LaboratoryClincal Biomarkers Laboratory
Last NameTran
First NameViLinh
Address615 Michael St, suite 225
Submit Date2021-10-06
Total Subjects527
Study CommentsBoth CHEAR pooled plasma samples and Clinical Biomarker Laboratory pooled plasma samples were used
Raw Data AvailableYes
Raw Data File Type(s)raw(Thermo)
Chear StudyYes
Analysis Type DetailLC-MS
Release Date2022-10-07
Release Version1
ViLinh Tran ViLinh Tran application/zip

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Collection ID:CO002002
Collection Summary:Blood serum samples were collected from participants in the ESPINA cohort study at the time of collection for pesticide exposures, health outcomes and other blood and urine measures. Serum was obtained from blood vein draw in adolescents (12-17 years of age). Blood samples were collected in red top vacutainer tubes and sit upright for 30 minutes for clot formation, followed by centrifugation and removal of 500ul aliquots of serum to 1.8ml freezer tubes and stores in a -70C freezer. The samples were shipped on dry ice from the clinical centers to the CHEAR URR at Emory University.
Sample Type:plasma
Storage Conditions:Described in summary