Summary of Study ST003104

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001927. The data can be accessed directly via it's Project DOI: 10.21228/M8N42X This work is supported by NIH grant, U2C- DK119886.

See: https://www.metabolomicsworkbench.org/about/howtocite.php

This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.

Perform statistical analysis  |  Show all samples  |  Show named metabolites  |  Download named metabolite data  
Download mwTab file (text)   |  Download mwTab file(JSON)   |  Download data files (Contains raw data)
Study IDST003104
Study TitleMetabolomics studies on human cardiac samples
Study SummaryTargeted metabolomics was performed to measure polar metabolites in both positive and negative ionization mode on left ventricular tissue acquired from pre-mortem healthy donor hearts as classified by formal pathological examination and stored at the Sydney Heart Bank. The minimum number of observations for young (age ≤ 25 years) and old (age ≥ 50 years) cohorts using liquid chromatography-tandem mass spectrometry (LC-MS/MS).
Institute
University of Sydney
DepartmentMedicine and Health
Last NameKoay
First NameYen Chin
AddressCharles Perkin Centre
Emailyen.koay@sydney.edu.au
Phone+61486275851
Submit Date2023-09-10
Num Groups2
Total Subjects25
Num Males15
Num Females10
Raw Data AvailableYes
Raw Data File Type(s)mzML
Analysis Type DetailAPI
Release Date2024-03-11
Release Version1
Yen Chin Koay Yen Chin Koay
https://dx.doi.org/10.21228/M8N42X
ftp://www.metabolomicsworkbench.org/Studies/ application/zip

Select appropriate tab below to view additional metadata details:

Collection:

Collection ID:CO003212
Collection Summary:Control donor hearts that were considered suitable for transplantation but ultimately not used due to factors such as transport issues, immune mismatches, and size discrepancies between donor and recipient, rather than being post-mortem specimens were collected in this study. These hearts came from individuals who died of non-cardiac reasons and had no risk factors for heart disease, including having a BMI under 30. Following a thorough pathological review, these hearts were confirmed to be structurally normal through histological evaluation. Left ventricular (LV) samples were taken directly in the operating room, immediately snap-frozen in liquid nitrogen at -196°C, and then stored at the Sydney Heart Bank at the University of Sydney, at temperatures ranging from -170 to -180°C. This collection process received the ethical green light from the University of Sydney's Ethics Committee (USYD # 2021/122).
Sample Type:Heart
Storage Conditions:Described in summary
  logo