Summary of study ST000082

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000058. The data can be accessed directly via it's Project DOI: 10.21228/M80018 This work is supported by NIH grant, U2C- DK119886.

See: https://www.metabolomicsworkbench.org/about/howtocite.php

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Study IDST000082
Study TitleMetabolic Profiling of Visceral and Subcutaneous Adipose Tissue from Colorectal Cancer Patients: UHPLC-QTOF MS analyis of serum samples
Study Typebiomarker study
Study SummaryThis West Coast Metabolomics Center pilot and feasibility project was granted to Johanna Lampe (Fred Hutchinson Cancer Research Center at Univ. of Washington, Seattle). In the current investigation, unbiased profiling of the metabolome and lipidome of adipose tissue samples (visceral(VAT) and subcutaenous (SAT)) and serum of 50 CRC patients, including stages I-IV, from the Fred Hutchinson Cancer Center (Seattle,WA) and the German Cancer Research Center (Heidelberg, Germany) was conducted. The lipidome and metabolome of adipose tissue (VAT/SAT) and serum were analyzed using established UPLC-QTOFMS analysis and GC-TOFMS analyses, respectively.  The primary objectives of this project were to 1) compare the metabolome and lipidome of matched VAT and SAT adipose tissue of n=50 Colorectal Cancer Cell (CRC) patients, 2) characterize the associations between the lipidome and metabolome in adipose tissue (VAT/SAT) and serum of n=50 CRC patients and 3) test the associations between the lipidome/metabolome of VAT and serum with the tumor stage of CRC patients. 
Institute
University of California, Davis
DepartmentGenome and Biomedical Sciences Facility
LaboratoryWCMC Metabolomics Core
Last NameFiehn
First NameOliver
Address1315 Genome and Biomedical Sciences Facility 451 Health Sciences Drive Davis, CA 95616
Emailofiehn@ucdavis.edu
Phone(530) 754-8258
Submit Date2014-06-11
Num Groups1
Total Subjects59
Study CommentsLipidomics profiles for study
This is the serum part of the study
Label-ID os conserved for all parts of the study
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Raw Data AvailableYes
Raw Data File Type(s).cd,.cG,.bin,.xml,.stg
Uploaded File Size14 G
Analysis Type DetailLC-MS
Release Date2014-07-25
Release Version1
Oliver Fiehn Oliver Fiehn
https://dx.doi.org/10.21228/M80018
ftp://www.metabolomicsworkbench.org/Studies/ application/zip

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Factors:

Subject type: Human; Subject species: Homo sapiens (Factor headings shown in green)

mb_sample_id local_sample_id Source
SA004190QC01Pooled Plasma
SA004191QC02Pooled Plasma
SA004192QC03Pooled Plasma
SA004193S43Serum
SA004194S42Serum
SA004195S44Serum
SA004196S45Serum
SA004197S46Serum
SA004198S41Serum
SA004199S37Serum
SA004200S36Serum
SA004201S35Serum
SA004202S47Serum
SA004203S38Serum
SA004204S39Serum
SA004205S40Serum
SA004206S51Serum
SA004207S57Serum
SA004208S56Serum
SA004209S58Serum
SA004210S59Serum
SA004211Pooled MSMS.dSerum
SA004212S55Serum
SA004213S54Serum
SA004214S50Serum
SA004215S49Serum
SA004216S34Serum
SA004217S52Serum
SA004218S53Serum
SA004219S48Serum
SA004220S33Serum
SA004221S12Serum
SA004222S11Serum
SA004223S10Serum
SA004224S13Serum
SA004225S14Serum
SA004226S16Serum
SA004227S15Serum
SA004228S9Serum
SA004229S8Serum
SA004230S3Serum
SA004231S2Serum
SA004232S4Serum
SA004233S5Serum
SA004234S7Serum
SA004235S6Serum
SA004236S17Serum
SA004237S18Serum
SA004238S28Serum
SA004239S27Serum
SA004240S29Serum
SA004241S30Serum
SA004242S32Serum
SA004243S31Serum
SA004244S26Serum
SA004245S25Serum
SA004246S20Serum
SA004247S19Serum
SA004248S21Serum
SA004249S22Serum
SA004250S24Serum
SA004251S23Serum
SA004252S1Serum
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