Summary of Study ST001204

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000809. The data can be accessed directly via it's Project DOI: 10.21228/M83X38 This work is supported by NIH grant, U2C- DK119886.

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Study IDST001204
Study TitlePeroxide antimalarial extended treatment timecourse on trophozoite-stage P. falciparum parasites
Study SummaryRed blood cells (RBCs) infected with trophozoite stage P. falciparum parasites (3D7 strain) at 10% parasitaemia and 2% haematocrit were treated with OZ277 (300 nM), OZ439 (300 nM), DHA (100 nM) or vehicle (0.03% DMSO). This was a 4-timepoint study, with samples taken 0, 3, 6 and 9 h after drug or vehicle addition. Samples treated with vehicle acted as the untreated control. Samples from drug treated uninfected RBCs were also taken to ensure the observed drug effects were parasite specific.
Institute
Monash University
Last NameGiannangelo
First NameCarlo
Address381 Royal Parade, Parkville, Victoria, 3052, Australia
Emailcarlo.giannangelo@monash.edu
Phone99039282
Submit Date2019-06-25
Raw Data AvailableYes
Raw Data File Type(s)raw(Thermo)
Analysis Type DetailLC-MS
Release Date2019-07-17
Release Version1
Carlo Giannangelo Carlo Giannangelo
https://dx.doi.org/10.21228/M83X38
ftp://www.metabolomicsworkbench.org/Studies/ application/zip

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Factors:

Subject type: Cultured cells; Subject species: Plasmodium falciparum;Homo sapiens (Factor headings shown in green)

mb_sample_id local_sample_id cell_type treatment treatment_duration_(h)
SA084646DHA_iRBC_0h_BiRBC DHA -
SA084647DHA_iRBC_0h_CiRBC DHA -
SA084648DHA_iRBC_0h_DiRBC DHA -
SA084649DHA_iRBC_3h_CiRBC DHA 3
SA084650DHA_iRBC_3h_BiRBC DHA 3
SA084651DHA_iRBC_3h_DiRBC DHA 3
SA084652DHA_iRBC_6h_BiRBC DHA 6
SA084653DHA_iRBC_6h_DiRBC DHA 6
SA084654DHA_iRBC_6h_CiRBC DHA 6
SA084655DHA_iRBC_9h_DiRBC DHA 9
SA084656DHA_iRBC_9h_BiRBC DHA 9
SA084657DHA_iRBC_9h_CiRBC DHA 9
SA084658DMSO_iRBC_0h_BiRBC DMSO -
SA084659DMSO_iRBC_0h_DiRBC DMSO -
SA084660DMSO_iRBC_0h_CiRBC DMSO -
SA084661DMSO_iRBC_3h_CiRBC DMSO 3
SA084662DMSO_iRBC_3h_DiRBC DMSO 3
SA084663DMSO_iRBC_3h_BiRBC DMSO 3
SA084664DMSO_iRBC_6h_CiRBC DMSO 6
SA084665DMSO_iRBC_6h_DiRBC DMSO 6
SA084666DMSO_iRBC_6h_BiRBC DMSO 6
SA084667DMSO_iRBC_9h_DiRBC DMSO 9
SA084668DMSO_iRBC_9h_BiRBC DMSO 9
SA084669DMSO_iRBC_9h_CiRBC DMSO 9
SA084670OZ277_iRBC_0h_BiRBC OZ277 -
SA084671OZ277_iRBC_0h_DiRBC OZ277 -
SA084672OZ277_iRBC_0h_CiRBC OZ277 -
SA084673OZ277_iRBC_3h_CiRBC OZ277 3
SA084674OZ277_iRBC_3h_BiRBC OZ277 3
SA084675OZ277_iRBC_3h_DiRBC OZ277 3
SA084676OZ277_iRBC_6h_CiRBC OZ277 6
SA084677OZ277_iRBC_6h_BiRBC OZ277 6
SA084678OZ277_iRBC_6h_DiRBC OZ277 6
SA084679OZ277_iRBC_9h_BiRBC OZ277 9
SA084680OZ277_iRBC_9h_CiRBC OZ277 9
SA084681OZ277_iRBC_9h_DiRBC OZ277 9
SA084682OZ439_iRBC_0h_CiRBC OZ439 -
SA084683OZ439_iRBC_0h_DiRBC OZ439 -
SA084684OZ439_iRBC_0h_BiRBC OZ439 -
SA084685OZ439_iRBC_3h_DiRBC OZ439 3
SA084686OZ439_iRBC_3h_BiRBC OZ439 3
SA084687OZ439_iRBC_3h_CiRBC OZ439 3
SA084688OZ439_iRBC_6h_DiRBC OZ439 6
SA084689OZ439_iRBC_6h_CiRBC OZ439 6
SA084690OZ439_iRBC_6h_BiRBC OZ439 6
SA084691OZ439_iRBC_9h_DiRBC OZ439 9
SA084692OZ439_iRBC_9h_CiRBC OZ439 9
SA084693OZ439_iRBC_9h_BiRBC OZ439 9
SA084694DHA_unRBC_0h_DunRBC DHA -
SA084695DHA_unRBC_0h_CunRBC DHA -
SA084696DHA_unRBC_0h_BunRBC DHA -
SA084697DHA_unRBC_3h_CunRBC DHA 3
SA084698DHA_unRBC_3h_BunRBC DHA 3
SA084699DHA_unRBC_3h_DunRBC DHA 3
SA084700DHA_unRBC_6h_DunRBC DHA 6
SA084701DHA_unRBC_6h_BunRBC DHA 6
SA084702DHA_unRBC_6h_CunRBC DHA 6
SA084703DHA_unRBC_9h_CunRBC DHA 9
SA084704DHA_unRBC_9h_DunRBC DHA 9
SA084705DHA_unRBC_9h_BunRBC DHA 9
SA084706DMSO_unRBC_0h_CunRBC DMSO -
SA084707DMSO_unRBC_0h_DunRBC DMSO -
SA084708DMSO_unRBC_0h_BunRBC DMSO -
SA084709DMSO_unRBC_3h_BunRBC DMSO 3
SA084710DMSO_unRBC_3h_DunRBC DMSO 3
SA084711DMSO_unRBC_3h_CunRBC DMSO 3
SA084712DMSO_unRBC_6h_BunRBC DMSO 6
SA084713DMSO_unRBC_6h_DunRBC DMSO 6
SA084714DMSO_unRBC_6h_CunRBC DMSO 6
SA084715DMSO_unRBC_9h_BunRBC DMSO 9
SA084716DMSO_unRBC_9h_CunRBC DMSO 9
SA084717DMSO_unRBC_9h_DunRBC DMSO 9
SA084718OZ277_unRBC_0h_CunRBC OZ277 -
SA084719OZ277_unRBC_0h_DunRBC OZ277 -
SA084720OZ277_unRBC_0h_BunRBC OZ277 -
SA084721OZ277_unRBC_3h_BunRBC OZ277 3
SA084722OZ277_unRBC_3h_DunRBC OZ277 3
SA084723OZ277_unRBC_3h_CunRBC OZ277 3
SA084724OZ277_unRBC_6h_DunRBC OZ277 6
SA084725OZ277_unRBC_6h_BunRBC OZ277 6
SA084726OZ277_unRBC_6h_CunRBC OZ277 6
SA084727OZ277_unRBC_9h_BunRBC OZ277 9
SA084728OZ277_unRBC_9h_DunRBC OZ277 9
SA084729OZ277_unRBC_9h_CunRBC OZ277 9
SA084730OZ439_unRBC_0h_DunRBC OZ439 -
SA084731OZ439_unRBC_0h_BunRBC OZ439 -
SA084732OZ439_unRBC_0h_CunRBC OZ439 -
SA084733OZ439_unRBC_3h_DunRBC OZ439 3
SA084734OZ439_unRBC_3h_CunRBC OZ439 3
SA084735OZ439_unRBC_3h_BunRBC OZ439 3
SA084736OZ439_unRBC_6h_CunRBC OZ439 6
SA084737OZ439_unRBC_6h_DunRBC OZ439 6
SA084738OZ439_unRBC_6h_BunRBC OZ439 6
SA084739OZ439_unRBC_9h_CunRBC OZ439 9
SA084740OZ439_unRBC_9h_BunRBC OZ439 9
SA084741OZ439_unRBC_9h_DunRBC OZ439 9
Showing results 1 to 96 of 96
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