Summary of Study ST001735

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001110. The data can be accessed directly via it's Project DOI: 10.21228/M8739H This work is supported by NIH grant, U2C- DK119886.

See: https://www.metabolomicsworkbench.org/about/howtocite.php

This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.

Study ID	ST001735
Study Title	The COVIDome Explorer Researcher Portal (Red Blood Cells)
Study Summary	COVID-19 pathology involves dysregulation of diverse molecular, cellular, and physiological processes. In order to expedite integrated and collaborative COVID-19 research, we completed multi-omics analysis of hospitalized COVID-19 patients including matched analysis of the whole blood transcriptome, plasma proteomics with two complementary platforms, cytokine profiling, plasma and red blood cell metabolomics, deep immune cell phenotyping by mass cytometry, and clinical data annotation. We refer to this multidimensional dataset as the COVIDome. We then created the COVIDome Explorer, an online researcher portal where the data can be analyzed and visualized in real time. We illustrate here the use of the COVIDome dataset through a multi-omics analysis of biosignatures associated with C-reactive protein (CRP), an established marker of poor prognosis in COVID-19, revealing associations between CRP levels and damage-associated molecular patterns, depletion of protective serpins, and mitochondrial metabolism dysregulation. We expect that the COVIDome Explorer will rapidly accelerate data sharing, hypothesis testing, and discoveries worldwide.
Institute	University of Colorado Anschutz Medical Campus
Last Name	Haines
First Name	Julie
Address	12801 E 17th Ave, Room 1303
Email	julie.haines@cuanschutz.edu
Phone	3037243339
Submit Date	2021-03-29
Raw Data Available	Yes
Raw Data File Type(s)	raw(Thermo)
Analysis Type Detail	LC-MS
Release Date	2021-04-09
Release Version	1

Select appropriate tab below to view additional metadata details:

Factors:

Subject type: Human; Subject species: Homo sapiens (Factor headings shown in green)

mb_sample_id	local_sample_id	COVID_Status	Sex	Age
SA162670	CUcovID_0037	Negative	Female	30
SA162671	CUcovID_0094	Negative	Female	31
SA162672	CUcovID_0079	Negative	Female	34
SA162673	CUcovID_0028	Negative	Female	34
SA162674	CUcovID_0027	Negative	Female	36
SA162675	CUcovID_0017	Negative	Female	36
SA162676	CUcovID_0039	Negative	Female	38
SA162677	CUcovID_0038	Negative	Female	39
SA162678	CUcovID_0006	Negative	Female	41
SA162679	CUcovID_0063	Negative	Female	43
SA162680	CUcovID_0095	Negative	Female	76
SA162681	CUcovID_0044	Negative	Female	80
SA162682	CUcovID_0086	Negative	Male	23
SA162683	CUcovID_0081	Negative	Male	25
SA162684	CUcovID_0084	Negative	Male	25
SA162685	CUcovID_0093	Negative	Male	26
SA162686	CUcovID_0091	Negative	Male	35
SA162687	CUcovID_0004	Negative	Male	38
SA162688	CUcovID_0051	Negative	Male	42
SA162689	CUcovID_0052	Negative	Male	43
SA162690	CUcovID_0083	Negative	Male	47
SA162691	CUcovID_0031	Negative	Male	50
SA162692	CUcovID_0073	Negative	Male	54
SA162693	CUcovID_0105	Negative	Male	59
SA162694	CUcovID_0048	Negative	Male	60
SA162695	CUcovID_0023	Negative	Male	63
SA162696	CUcovID_0076	Negative	Male	65
SA162697	CUcovID_0064	Negative	Male	66
SA162698	CUcovID_0072	Negative	Male	67
SA162699	CUcovID_0097	Negative	Male	71
SA162700	CUcovID_0082	Negative	Male	under 20
SA162701	CUcovID_0106	Positive	Female	21
SA162702	CUcovID_0087	Positive	Female	21
SA162703	CUcovID_0100	Positive	Female	23
SA162704	CUcovID_0035	Positive	Female	23
SA162705	CUcovID_0009	Positive	Female	25
SA162706	CUcovID_0033	Positive	Female	29
SA162707	CUcovID_0003	Positive	Female	29
SA162708	CUcovID_0080	Positive	Female	35
SA162709	CUcovID_0060	Positive	Female	38
SA162710	CUcovID_0008	Positive	Female	39
SA162711	CUcovID_0022	Positive	Female	39
SA162712	CUcovID_0075	Positive	Female	41
SA162713	CUcovID_0090	Positive	Female	43
SA162714	CUcovID_0002	Positive	Female	44
SA162715	CUcovID_0018	Positive	Female	45
SA162716	CUcovID_0045	Positive	Female	46
SA162717	CUcovID_0077	Positive	Female	49
SA162718	CUcovID_0071	Positive	Female	49
SA162719	CUcovID_0014	Positive	Female	53
SA162720	CUcovID_0026	Positive	Female	53
SA162721	CUcovID_0055	Positive	Female	54
SA162722	CUcovID_0025	Positive	Female	56
SA162723	CUcovID_0069	Positive	Female	56
SA162724	CUcovID_0102	Positive	Female	57
SA162725	CUcovID_0019	Positive	Female	60
SA162726	CUcovID_0040	Positive	Female	61
SA162727	CUcovID_0074	Positive	Female	61
SA162728	CUcovID_0092	Positive	Female	under 20
SA162729	CUcovID_0078	Positive	Female	under 20
SA162730	CUcovID_0088	Positive	Female	under 20
SA162731	CUcovID_0024	Positive	Female	under 20
SA162732	CUcovID_0085	Positive	Female	under 20
SA162733	CUcovID_0050	Positive	Female	under 20
SA162734	CUcovID_0101	Positive	Male	20
SA162735	CUcovID_0043	Positive	Male	21
SA162736	CUcovID_0021	Positive	Male	24
SA162737	CUcovID_0107	Positive	Male	26
SA162738	CUcovID_0007	Positive	Male	28
SA162739	CUcovID_0109	Positive	Male	30
SA162740	CUcovID_0041	Positive	Male	33
SA162741	CUcovID_0065	Positive	Male	34
SA162742	CUcovID_0016	Positive	Male	41
SA162743	CUcovID_0012	Positive	Male	42
SA162744	CUcovID_0013	Positive	Male	42
SA162745	CUcovID_0096	Positive	Male	43
SA162746	CUcovID_0108	Positive	Male	45
SA162747	CUcovID_0054	Positive	Male	46
SA162748	CUcovID_0029	Positive	Male	47
SA162749	CUcovID_0020	Positive	Male	50
SA162750	CUcovID_0049	Positive	Male	50
SA162751	CUcovID_0061	Positive	Male	51
SA162752	CUcovID_0068	Positive	Male	52
SA162753	CUcovID_0046	Positive	Male	54
SA162754	CUcovID_0042	Positive	Male	55
SA162755	CUcovID_0059	Positive	Male	55
SA162756	CUcovID_0047	Positive	Male	59
SA162757	CUcovID_0030	Positive	Male	60
SA162758	CUcovID_0089	Positive	Male	60
SA162759	CUcovID_0098	Positive	Male	61
SA162760	CUcovID_0005	Positive	Male	61
SA162761	CUcovID_0070	Positive	Male	69
SA162762	CUcovID_0010	Positive	Male	71
SA162763	CUcovID_0001	Positive	Male	77
SA162764	CUcovID_0104	Positive	Male	79
SA162765	CUcovID_0011	Positive	Male	79
SA162766	CUcovID_0056	Positive	Male	under 20
SA162767	CUcovID_0036	Positive	Male	under 20
SA162768	CUcovID_0057	Positive	Male	under 20
SA162769	CUcovID_0062	Positive	Male	under 20