Summary of Study ST002196

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001400. The data can be accessed directly via it's Project DOI: 10.21228/M8RM5T This work is supported by NIH grant, U2C- DK119886.

See: https://www.metabolomicsworkbench.org/about/howtocite.php

This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.

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Study IDST002196
Study TitleMetabolic signature of idiopathic inflammatory myopathy
Study SummaryObjective of this study was to find Metabolic signature of idiopathic inflammatory myopathy (IIM). We used the serum samples of healthy control, IIM, ankylosing spondylitis. Metabolites were quantified using biocrates p180 kit. First, we found IIM specific metabolites by using ANOVA with post-hoc analysis. With set of metabolite panel, we made prediction model using logistic regression (LR), support vector machine (SVM), and random forest (RF). We found 7 metabolites as biomarker for classifying IIM from healthy control and ankylosing spondylitis. Also, we validate our model using 5 cross validation method. Out set of metabolites showed the AUC values of 0.955 (LR), 0.908 (RF) and 0.918 (SVM).
Institute
Seoul National University
Last NameKang
First NameJihyun
Address502ho Intergrative Biomedical Education Research Building, 101 Deahakro, Jongro-gu, Seoul, 03080, Korea, South Korea
Emailjikang@snu.ac.kr
Phone+821071014069
Submit Date2022-06-09
Raw Data AvailableYes
Raw Data File Type(s)wiff
Analysis Type DetailLC-MS
Release Date2022-07-14
Release Version1
Jihyun Kang Jihyun Kang
https://dx.doi.org/10.21228/M8RM5T
ftp://www.metabolomicsworkbench.org/Studies/ application/zip

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Factors:

Subject type: Human; Subject species: Homo sapiens (Factor headings shown in green)

mb_sample_id local_sample_id Factor
SA21048367AS
SA21048468AS
SA21048570AS
SA21048665AS
SA21048769AS
SA21048864AS
SA21048961AS
SA21049062AS
SA21049163AS
SA21049271AS
SA21049372AS
SA21049478AS
SA21049579AS
SA21049680AS
SA21049777AS
SA21049876AS
SA21049973AS
SA21050074AS
SA21050175AS
SA2105022_61AS
SA21050366AS
SA2105042_68AS
SA2105052_69AS
SA2105062_62AS
SA2105072_67AS
SA2105082_70AS
SA2105092_63AS
SA2105102_65AS
SA2105112_64AS
SA2105122_66AS
SA2105132_54Healthy control
SA2105142_55Healthy control
SA2105152_56Healthy control
SA2105162_53Healthy control
SA2105172_60Healthy control
SA2105182_57Healthy control
SA2105192_58Healthy control
SA2105202_59Healthy control
SA2105212_51Healthy control
SA2105222_52Healthy control
SA2105232_49IIM
SA2105242_48IIM
SA2105252_50IIM
SA2105262_77IIM
SA2105272_73IIM
SA2105282_72IIM
SA2105292_71IIM
SA2105302_47IIM
SA2105312_74IIM
SA2105322_75IIM
SA2105332_79IIM
SA2105342_78IIM
SA2105352_76IIM
SA2105362_80IIM
SA2105372_32IIM
SA21053851IIM
SA21053950IIM
SA21054049IIM
SA21054152IIM
SA21054253IIM
SA21054355IIM
SA21054454IIM
SA21054548IIM
SA21054647IIM
SA21054742IIM
SA21054841IIM
SA21054940IIM
SA21055043IIM
SA21055144IIM
SA21055246IIM
SA21055345IIM
SA21055456IIM
SA21055557IIM
SA2105562_41IIM
SA2105572_40IIM
SA2105582_38IIM
SA2105592_42IIM
SA2105602_43IIM
SA2105612_45IIM
SA2105622_44IIM
SA2105632_36IIM
SA2105642_34IIM
SA21056560IIM
SA21056659IIM
SA21056758IIM
SA2105682_26IIM
SA2105692_28IIM
SA21057039IIM
SA2105712_30IIM
SA2105722_46IIM
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