Summary of Study ST002261

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001443. The data can be accessed directly via it's Project DOI: 10.21228/M86H66 This work is supported by NIH grant, U2C- DK119886.

See: https://www.metabolomicsworkbench.org/about/howtocite.php

This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.

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Study IDST002261
Study TitleInvestigating metabolic pathways of pediatric obesity (urine)
Study SummaryThe pediatric obesity influences all the organs and is closely linked to an increased risk of diverse diseases such as diabetes, cardiovascular, stroke, social problems and depression. Therefore, there is needed to diverse study for effective methods for the prevention and treatment of pediatric obesity. Diverse evidences suggest that gut microbiome and its metabolites affect metabolic disease such as obesity, diabetes, and heart disease. Previous studies in human and fecal transplantation experiments in animal models identified connections between the metabolic diseases and gut microbiota [4]. Moreover, metabolites can be fulfilled as diagnostic, prognostic, and therapeutic targets for diseases. Thus, approaches using metagenomics and metabolomics have the potential to provide new insights into metabolomic pathways of the diseases and help personalized and efficient treatments. In this study, we aimed to investigate metabolomic pathways of pediatric obesity analyzing both metabolome and microbiome profiles. In addition, we proceeded obese intervention with obese children to examine underlying metabolomic pathways related to effect of the intervention.
Institute
Seoul National University College of Medicine and Hospital
DepartmentDepartment of Clinical Pharmacology and Therapeutics
Last NameLee
First NameYujin
Address101 Daehak-ro, Jongno-gu, Seoul 110-799, Korea, Seoul, Seoul, 03080, Korea, South
Emailyoojinlee@snu.ac.kr
Phone+82-10-3380-4686
Submit Date2022-07-04
Raw Data AvailableYes
Raw Data File Type(s)smp
Analysis Type DetailGC-MS
Release Date2023-01-04
Release Version1
Yujin Lee Yujin Lee
https://dx.doi.org/10.21228/M86H66
ftp://www.metabolomicsworkbench.org/Studies/ application/zip

Select appropriate tab below to view additional metadata details:

Factors:

Subject type: Human; Subject species: Homo sapiens (Factor headings shown in green)

mb_sample_id local_sample_id Gender Group
SA217274N10F Normal
SA217275N12F Normal
SA217276N14F Normal
SA217277N08F Normal
SA217278N19F Normal
SA217279N04F Normal
SA217280N22F Normal
SA217281M10F Obe
SA217282M11F Obe
SA217283M06F Obe
SA217284M07F Obe
SA217285M09F Obe
SA217286M14F Obe
SA217287M19F Obe
SA217288M32F Obe
SA217289M41F Obe
SA217290M31F Obe
SA217291M29F Obe
SA217292M02F Obe
SA217293M25F Obe
SA217294M16F Obe
SA217295M08F Obe
SA217296N11M Normal
SA217297N13M Normal
SA217298N16M Normal
SA217299N05M Normal
SA217300N06M Normal
SA217301N09M Normal
SA217302N07M Normal
SA217303N17M Normal
SA217304N15M Normal
SA217305N01M Normal
SA217306N03M Normal
SA217307N21M Normal
SA217308N20M Normal
SA217309N02M Normal
SA217310N18M Normal
SA217311M42M Obe
SA217312M28M Obe
SA217313M35M Obe
SA217314M40M Obe
SA217315M26M Obe
SA217316M37M Obe
SA217317M36M Obe
SA217318M33M Obe
SA217319M20M Obe
SA217320M12M Obe
SA217321M15M Obe
SA217322M05M Obe
SA217323M04M Obe
SA217324M03M Obe
SA217325M17M Obe
SA217326M18M Obe
SA217327M23M Obe
SA217328M22M Obe
SA217329M21M Obe
SA217330M01M Obe
SA217331M24M Obe
Showing results 1 to 58 of 58
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