Summary of Study ST002619

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001020. The data can be accessed directly via it's Project DOI: 10.21228/M8V97D This work is supported by NIH grant, U2C- DK119886.

See: https://www.metabolomicsworkbench.org/about/howtocite.php

This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.

Study ID	ST002619
Study Title	MoTrPAC: Endurance exercise training study in young adult rats, Tissue:Brown Adipose - Targeted Ethanolamides
Study Summary	The goal of the endurance exercise training study in young adult rats (internal code: PASS1B-06) was to perform exercise training studies in adult (6 month) F344 rats, and from these rats collect as many tissues as feasible in order to provide high quality samples for detailed analysis by chemical analysis sites. Tissues were collected from 10-12 rats sedentary control rats concurrent with the collection of the 8-week training groups. The 8-week training group and controls were from the same cohort and same age at euthanasia (either 8). For the older age group, an additional set of controls (n=5-6) were collected with the 1-2 week training group. Rats were either sedentary or underwent an exercise training program. Rats were exercised on the rodent treadmill 5 days per week using a progressive training protocol designed to exercise the rats at approximately 70% of VO2max as outlined in the Table on the next page. Training was performed no earlier than 10:00 am and no later than 5:00 pm over 5 consecutive days per week. Training was initiated with the treadmill set at 70% of VO2 max (see tables) and 5 degrees grade for 20 minutes. The duration of exercise was increased by one minute each day until day 31 of training (start of week 7), when a duration of 50 min was reached. Speed and grade of each training session increased in larger increments due to treadmill parameters. The highest intensity and duration of training began on day 31. This intensity was maintained for the final 10 days of the protocol to ensure steady state had been achieved. If any rats were unable to perform at least 4 days of training per week they were removed from the study and euthanized. It is important to note that the starting treadmill speed varied depending on the sex and age of the rat. The initial and maximum speeds were based on VO2max measurements obtained during the pre-training testing of the compliant rats. Rats assigned to the control group followed a schedule similar to the training group. They were placed in one lane on the treadmill for 15 minutes/day, 5 days per week. The treadmill was set at 0 m/min at an incline that corresponded to the incline being used by the training group.
Institute	Emory University
Department	Biochemistry
Laboratory	Integrated Lipidomics and Metabolomics Core
Last Name	Ortlund
First Name	Eric
Address	1510 Clifton Rd. NE, Room G235, Atlanta, GA 30322
Email	eortlun@emory.edu
Phone	(404) 727-5014
Submit Date	2023-04-28
Raw Data Available	Yes
Raw Data File Type(s)	TBD
Analysis Type Detail	LC-MS
Release Date	2023-10-06
Release Version	1

Select appropriate tab below to view additional metadata details:

Factors:

Subject type: Mammal; Subject species: Rattus norvegicus (Factor headings shown in green)

mb_sample_id	local_sample_id	Group	Timepoint	Sex
SA261181	90265016908	Control	8 weeks of training or control time	Female
SA261182	90266016908	Control	8 weeks of training or control time	Female
SA261183	90252016908	Control	8 weeks of training or control time	Female
SA261184	90229016908	Control	8 weeks of training or control time	Male
SA261185	90217016908	Control	8 weeks of training or control time	Male
SA261186	90232016908	Control	8 weeks of training or control time	Male
SA261187	90237016908	Control	8 weeks of training or control time	Male
SA261188	90239016908	Control	8 weeks of training or control time	Male
SA261189	QC_blank_46	QC-Blank	0 hour	-
SA261190	QC_blank_49	QC-Blank	0 hour	-
SA261191	QC_blank_50	QC-Blank	0 hour	-
SA261192	QC_blank_59	QC-Blank	0 hour	-
SA261193	QC_blank_45	QC-Blank	0 hour	-
SA261194	QC_blank_4	QC-Blank	0 hour	-
SA261195	QC_blank_6	QC-Blank	0 hour	-
SA261196	QC_blank_60	QC-Blank	0 hour	-
SA261197	QC_blank_44	QC-Blank	0 hour	-
SA261198	QC_blank_5	QC-Blank	0 hour	-
SA261199	QC_Standard_58	QC-ExternalStandard	0 hour	-
SA261200	QC_Standard_57	QC-ExternalStandard	0 hour	-
SA261201	QC_Standard_56	QC-ExternalStandard	0 hour	-
SA261202	QC_Standard_51	QC-ExternalStandard	0 hour	-
SA261203	QC_Standard_54	QC-ExternalStandard	0 hour	-
SA261204	QC_Standard_55	QC-ExternalStandard	0 hour	-
SA261205	QC_Standard_52	QC-ExternalStandard	0 hour	-
SA261206	QC_Standard_53	QC-ExternalStandard	0 hour	-
SA261207	QC_48	QC-Pooled	0 hour	-
SA261208	QC_18	QC-Pooled	0 hour	-
SA261209	QC_40	QC-Pooled	0 hour	-
SA261210	QC_29	QC-Pooled	0 hour	-
SA261211	QC_7	QC-Pooled	0 hour	-
SA261212	QC_prerun_3	QC-PreRun	0 hour	-
SA261213	QC_prerun_1	QC-PreRun	0 hour	-
SA261214	QC_prerun_2	QC-PreRun	0 hour	-
SA261215	QC_SRM	QC-Reference	0 hour	-
SA261216	90567016908	Training	1 week of training or control time	Female
SA261217	90571016908	Training	1 week of training or control time	Female
SA261218	90560016908	Training	1 week of training or control time	Female
SA261219	90430016908	Training	1 week of training or control time	Male
SA261220	90426016908	Training	1 week of training or control time	Male
SA261221	90421016908	Training	1 week of training or control time	Male
SA261222	90423016908	Training	1 week of training or control time	Male
SA261223	90587016908	Training	2 weeks of training	Female
SA261224	90581016908	Training	2 weeks of training	Female
SA261225	90585016908	Training	2 weeks of training	Female
SA261226	90578016908	Training	2 weeks of training	Female
SA261227	90576016908	Training	2 weeks of training	Female
SA261228	90439016908	Training	2 weeks of training	Male
SA261229	90449016908	Training	2 weeks of training	Male
SA261230	90450016908	Training	2 weeks of training	Male
SA261231	90441016908	Training	2 weeks of training	Male
SA261232	90444016908	Training	2 weeks of training	Male
SA261233	90416016908	Training	4 weeks of training	Female
SA261234	90420016908	Training	4 weeks of training	Female
SA261235	90283016908	Training	4 weeks of training	Male
SA261236	90289016908	Training	4 weeks of training	Male
SA261237	90280016908	Training	4 weeks of training	Male
SA261238	90281016908	Training	4 weeks of training	Male
SA261239	90251016908	Training	8 weeks of training or control time	Female
SA261240	90225016908	Training	8 weeks of training or control time	Male

Showing results 1 to 60 of 60

Showing results 1 to 60 of 60