Summary of Study ST002625

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001020. The data can be accessed directly via it's Project DOI: 10.21228/M8V97D This work is supported by NIH grant, U2C- DK119886.

See: https://www.metabolomicsworkbench.org/about/howtocite.php

This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.

Study ID	ST002625
Study Title	MoTrPAC: Endurance exercise training study in young adult rats, Tissue:White Adipose - Targeted Nucleotides
Study Summary	The goal of the endurance exercise training study in young adult rats (internal code: PASS1B-06) was to perform exercise training studies in adult (6 month) F344 rats, and from these rats collect as many tissues as feasible in order to provide high quality samples for detailed analysis by chemical analysis sites. Tissues were collected from 10-12 rats sedentary control rats concurrent with the collection of the 8-week training groups. The 8-week training group and controls were from the same cohort and same age at euthanasia (either 8). For the older age group, an additional set of controls (n=5-6) were collected with the 1-2 week training group. Rats were either sedentary or underwent an exercise training program. Rats were exercised on the rodent treadmill 5 days per week using a progressive training protocol designed to exercise the rats at approximately 70% of VO2max as outlined in the Table on the next page. Training was performed no earlier than 10:00 am and no later than 5:00 pm over 5 consecutive days per week. Training was initiated with the treadmill set at 70% of VO2 max (see tables) and 5 degrees grade for 20 minutes. The duration of exercise was increased by one minute each day until day 31 of training (start of week 7), when a duration of 50 min was reached. Speed and grade of each training session increased in larger increments due to treadmill parameters. The highest intensity and duration of training began on day 31. This intensity was maintained for the final 10 days of the protocol to ensure steady state had been achieved. If any rats were unable to perform at least 4 days of training per week they were removed from the study and euthanized. It is important to note that the starting treadmill speed varied depending on the sex and age of the rat. The initial and maximum speeds were based on VO2max measurements obtained during the pre-training testing of the compliant rats. Rats assigned to the control group followed a schedule similar to the training group. They were placed in one lane on the treadmill for 15 minutes/day, 5 days per week. The treadmill was set at 0 m/min at an incline that corresponded to the incline being used by the training group.
Institute	Duke University
Department	Duke Molecular Physiology Institute
Laboratory	Metabolomics Core Laboratory
Last Name	Newgard
First Name	Christopher
Address	300 N Duke St, Durham, NC 27701
Email	chris.newgard@duke.edu
Phone	(919) 668-6059
Submit Date	2023-04-25
Raw Data Available	Yes
Raw Data File Type(s)	TBD
Analysis Type Detail	LC-MS
Release Date	2023-10-06
Release Version	1

Select appropriate tab below to view additional metadata details:

Factors:

Subject type: Mammal; Subject species: Rattus norvegicus (Factor headings shown in green)

mb_sample_id	local_sample_id	Group	Timepoint	Sex
SA261507	90245017012	Control	8 weeks of training or control time	Female
SA261508	90248017012	Control	8 weeks of training or control time	Female
SA261509	90252017012	Control	8 weeks of training or control time	Female
SA261510	90266017012	Control	8 weeks of training or control time	Female
SA261511	90265017012	Control	8 weeks of training or control time	Female
SA261512	90232017012	Control	8 weeks of training or control time	Male
SA261513	90217017012	Control	8 weeks of training or control time	Male
SA261514	90229017012	Control	8 weeks of training or control time	Male
SA261515	90239017012	Control	8 weeks of training or control time	Male
SA261516	90237017012	Control	8 weeks of training or control time	Male
SA261517	80012817002_3	QC-ExternalStandard	0 hour	-
SA261518	80013827002_2	QC-ExternalStandard	0 hour	-
SA261519	80013827002_3	QC-ExternalStandard	0 hour	-
SA261520	80012817002_1	QC-ExternalStandard	0 hour	-
SA261521	80012817002_2	QC-ExternalStandard	0 hour	-
SA261522	80013827002_4	QC-ExternalStandard	0 hour	-
SA261523	80012817002_4	QC-ExternalStandard	0 hour	-
SA261524	80013827002_1	QC-ExternalStandard	0 hour	-
SA261525	90571017012	Training	1 week of training or control time	Female
SA261526	90564017012	Training	1 week of training or control time	Female
SA261527	90567017012	Training	1 week of training or control time	Female
SA261528	90560017012	Training	1 week of training or control time	Female
SA261529	90559017012	Training	1 week of training or control time	Female
SA261530	90430017012	Training	1 week of training or control time	Male
SA261531	90423017012	Training	1 week of training or control time	Male
SA261532	90422017012	Training	1 week of training or control time	Male
SA261533	90421017012	Training	1 week of training or control time	Male
SA261534	90426017012	Training	1 week of training or control time	Male
SA261535	90576017012	Training	2 weeks of training	Female
SA261536	90585017012	Training	2 weeks of training	Female
SA261537	90578017012	Training	2 weeks of training	Female
SA261538	90587017012	Training	2 weeks of training	Female
SA261539	90581017012	Training	2 weeks of training	Female
SA261540	90441017012	Training	2 weeks of training	Male
SA261541	90449017012	Training	2 weeks of training	Male
SA261542	90450017012	Training	2 weeks of training	Male
SA261543	90439017012	Training	2 weeks of training	Male
SA261544	90444017012	Training	2 weeks of training	Male
SA261545	90410017012	Training	4 weeks of training	Female
SA261546	90420017012	Training	4 weeks of training	Female
SA261547	90416017012	Training	4 weeks of training	Female
SA261548	90406017012	Training	4 weeks of training	Female
SA261549	90412017012	Training	4 weeks of training	Female
SA261550	90280017012	Training	4 weeks of training	Male
SA261551	90289017012	Training	4 weeks of training	Male
SA261552	90281017012	Training	4 weeks of training	Male
SA261553	90283017012	Training	4 weeks of training	Male
SA261554	90292017012	Training	4 weeks of training	Male
SA261555	90258017012	Training	8 weeks of training or control time	Female
SA261556	90259017012	Training	8 weeks of training or control time	Female
SA261557	90251017012	Training	8 weeks of training or control time	Female
SA261558	90254017012	Training	8 weeks of training or control time	Female
SA261559	90267017012	Training	8 weeks of training or control time	Female
SA261560	90222017012	Training	8 weeks of training or control time	Male
SA261561	90218017012	Training	8 weeks of training or control time	Male
SA261562	90223017012	Training	8 weeks of training or control time	Male
SA261563	90225017012	Training	8 weeks of training or control time	Male
SA261564	90227017012	Training	8 weeks of training or control time	Male

Showing results 1 to 58 of 58

Showing results 1 to 58 of 58