Summary of Study ST002630

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001020. The data can be accessed directly via it's Project DOI: 10.21228/M8V97D This work is supported by NIH grant, U2C- DK119886.

See: https://www.metabolomicsworkbench.org/about/howtocite.php

This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.

Study ID	ST002630
Study Title	MoTrPAC: Endurance exercise training study in young adult rats, Tissue:Plasma - Untargeted Lipidomics, Reversed-Phase Negative
Study Summary	The goal of the endurance exercise training study in young adult rats (internal code: PASS1B-06) was to perform exercise training studies in adult (6 month) F344 rats, and from these rats collect as many tissues as feasible in order to provide high quality samples for detailed analysis by chemical analysis sites. Tissues were collected from 10-12 rats sedentary control rats concurrent with the collection of the 8-week training groups. The 8-week training group and controls were from the same cohort and same age at euthanasia (either 8). For the older age group, an additional set of controls (n=5-6) were collected with the 1-2 week training group. Rats were either sedentary or underwent an exercise training program. Rats were exercised on the rodent treadmill 5 days per week using a progressive training protocol designed to exercise the rats at approximately 70% of VO2max as outlined in the Table on the next page. Training was performed no earlier than 10:00 am and no later than 5:00 pm over 5 consecutive days per week. Training was initiated with the treadmill set at 70% of VO2 max (see tables) and 5 degrees grade for 20 minutes. The duration of exercise was increased by one minute each day until day 31 of training (start of week 7), when a duration of 50 min was reached. Speed and grade of each training session increased in larger increments due to treadmill parameters. The highest intensity and duration of training began on day 31. This intensity was maintained for the final 10 days of the protocol to ensure steady state had been achieved. If any rats were unable to perform at least 4 days of training per week they were removed from the study and euthanized. It is important to note that the starting treadmill speed varied depending on the sex and age of the rat. The initial and maximum speeds were based on VO2max measurements obtained during the pre-training testing of the compliant rats. Rats assigned to the control group followed a schedule similar to the training group. They were placed in one lane on the treadmill for 15 minutes/day, 5 days per week. The treadmill was set at 0 m/min at an incline that corresponded to the incline being used by the training group.
Institute	Georgia Institute of Technology
Department	Department of Chemistry and Biochemistry
Laboratory	Systems Mass Spectrometry Core (SyMSC)
Last Name	Facundo
First Name	Fernandez
Address	901 Atlantic Dr NW, Atlanta, GA 30332-0400
Email	facundo.fernandez@chemistry.gatech.edu
Phone	(404) 385-4432
Submit Date	2023-04-25
Raw Data Available	Yes
Raw Data File Type(s)	TBD
Analysis Type Detail	LC-MS
Release Date	2023-10-06
Release Version	1

Select appropriate tab below to view additional metadata details:

Factors:

Subject type: Mammal; Subject species: Rattus norvegicus (Factor headings shown in green)

mb_sample_id	local_sample_id	Group	Timepoint	Sex
SA267042	90248013106	Control	8 weeks of training or control time	Female
SA267043	90252013106	Control	8 weeks of training or control time	Female
SA267044	90266013106	Control	8 weeks of training or control time	Female
SA267045	90245013106	Control	8 weeks of training or control time	Female
SA267046	90265013106	Control	8 weeks of training or control time	Female
SA267047	90229013106	Control	8 weeks of training or control time	Male
SA267048	90239013106	Control	8 weeks of training or control time	Male
SA267049	90217013106	Control	8 weeks of training or control time	Male
SA267050	90237013106	Control	8 weeks of training or control time	Male
SA267051	90232013106	Control	8 weeks of training or control time	Male
SA267052	SampleBlank03	QC-Blank	0 hour	-
SA267053	SampleBlank01	QC-Blank	0 hour	-
SA267054	SampleBlank02	QC-Blank	0 hour	-
SA267055	SampleBlank05	QC-Blank	0 hour	-
SA267056	SampleBlank06	QC-Blank	0 hour	-
SA267057	SampleBlank04	QC-Blank	0 hour	-
SA267058	QC04	QC-Pooled	0 hour	-
SA267059	QC03	QC-Pooled	0 hour	-
SA267060	QC01	QC-Pooled	0 hour	-
SA267061	QC05	QC-Pooled	0 hour	-
SA267062	QC02	QC-Pooled	0 hour	-
SA267063	QC08	QC-Pooled	0 hour	-
SA267064	QC06	QC-Pooled	0 hour	-
SA267065	QC09	QC-Pooled	0 hour	-
SA267066	QC07	QC-Pooled	0 hour	-
SA267067	IPE_Reference_Plasma	QC-Reference	0 hour	-
SA267068	SED_Reference_Plasma	QC-Reference	0 hour	-
SA267069	IPE_Reference_Plasma02	QC-Reference	0 hour	-
SA267070	SED_Reference_Plasma02	QC-Reference	0 hour	-
SA267071	90560013106	Training	1 week of training or control time	Female
SA267072	90564013106	Training	1 week of training or control time	Female
SA267073	90567013106	Training	1 week of training or control time	Female
SA267074	90571013106	Training	1 week of training or control time	Female
SA267075	90559013106	Training	1 week of training or control time	Female
SA267076	90430013106	Training	1 week of training or control time	Male
SA267077	90423013106	Training	1 week of training or control time	Male
SA267078	90421013106	Training	1 week of training or control time	Male
SA267079	90426013106	Training	1 week of training or control time	Male
SA267080	90422013106	Training	1 week of training or control time	Male
SA267081	90581013106	Training	2 weeks of training	Female
SA267082	90585013106	Training	2 weeks of training	Female
SA267083	90587013106	Training	2 weeks of training	Female
SA267084	90578013106	Training	2 weeks of training	Female
SA267085	90576013106	Training	2 weeks of training	Female
SA267086	90450013106	Training	2 weeks of training	Male
SA267087	90439013106	Training	2 weeks of training	Male
SA267088	90449013106	Training	2 weeks of training	Male
SA267089	90441013106	Training	2 weeks of training	Male
SA267090	90444013106	Training	2 weeks of training	Male
SA267091	90410013106	Training	4 weeks of training	Female
SA267092	90406013106	Training	4 weeks of training	Female
SA267093	90412013106	Training	4 weeks of training	Female
SA267094	90416013106	Training	4 weeks of training	Female
SA267095	90420013106	Training	4 weeks of training	Female
SA267096	90280013106	Training	4 weeks of training	Male
SA267097	90281013106	Training	4 weeks of training	Male
SA267098	90283013106	Training	4 weeks of training	Male
SA267099	90292013106	Training	4 weeks of training	Male
SA267100	90289013106	Training	4 weeks of training	Male
SA267101	90254013106	Training	8 weeks of training or control time	Female
SA267102	90251013106	Training	8 weeks of training or control time	Female
SA267103	90259013106	Training	8 weeks of training or control time	Female
SA267104	90258013106	Training	8 weeks of training or control time	Female
SA267105	90267013106	Training	8 weeks of training or control time	Female
SA267106	90222013106	Training	8 weeks of training or control time	Male
SA267107	90218013106	Training	8 weeks of training or control time	Male
SA267108	90225013106	Training	8 weeks of training or control time	Male
SA267109	90227013106	Training	8 weeks of training or control time	Male
SA267110	90223013106	Training	8 weeks of training or control time	Male

Showing results 1 to 69 of 69

Showing results 1 to 69 of 69