Summary of Study ST002647

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001020. The data can be accessed directly via it's Project DOI: 10.21228/M8V97D This work is supported by NIH grant, U2C- DK119886.

See: https://www.metabolomicsworkbench.org/about/howtocite.php

This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.

Study ID	ST002647
Study Title	MoTrPAC: Endurance exercise training study in young adult rats, Tissue:Gastrocnemius - Untargeted Reversed-Phase Positive
Study Summary	The goal of the endurance exercise training study in young adult rats (internal code: PASS1B-06) was to perform exercise training studies in adult (6 month) F344 rats, and from these rats collect as many tissues as feasible in order to provide high quality samples for detailed analysis by chemical analysis sites. Tissues were collected from 10-12 rats sedentary control rats concurrent with the collection of the 8-week training groups. The 8-week training group and controls were from the same cohort and same age at euthanasia (either 8). For the older age group, an additional set of controls (n=5-6) were collected with the 1-2 week training group. Rats were either sedentary or underwent an exercise training program. Rats were exercised on the rodent treadmill 5 days per week using a progressive training protocol designed to exercise the rats at approximately 70% of VO2max as outlined in the Table on the next page. Training was performed no earlier than 10:00 am and no later than 5:00 pm over 5 consecutive days per week. Training was initiated with the treadmill set at 70% of VO2 max (see tables) and 5 degrees grade for 20 minutes. The duration of exercise was increased by one minute each day until day 31 of training (start of week 7), when a duration of 50 min was reached. Speed and grade of each training session increased in larger increments due to treadmill parameters. The highest intensity and duration of training began on day 31. This intensity was maintained for the final 10 days of the protocol to ensure steady state had been achieved. If any rats were unable to perform at least 4 days of training per week they were removed from the study and euthanized. It is important to note that the starting treadmill speed varied depending on the sex and age of the rat. The initial and maximum speeds were based on VO2max measurements obtained during the pre-training testing of the compliant rats. Rats assigned to the control group followed a schedule similar to the training group. They were placed in one lane on the treadmill for 15 minutes/day, 5 days per week. The treadmill was set at 0 m/min at an incline that corresponded to the incline being used by the training group.
Institute	University of Michigan
Department	Biomedical Research Core Facilities
Laboratory	Metabolomics core
Last Name	Burant
First Name	Charles
Address	6120 Brehm Tower,1000 Wall St., Ann Arbor, MI, 48105-5714
Email	burantc@med.umich.edu
Phone	(734) 232-0842
Submit Date	2023-05-01
Num Groups	65
Total Subjects	50
Raw Data Available	Yes
Raw Data File Type(s)	TBD
Analysis Type Detail	LC-MS
Release Date	2023-10-06
Release Version	1

Select appropriate tab below to view additional metadata details:

Factors:

Subject type: Mammal; Subject species: Rattus norvegicus (Factor headings shown in green)

mb_sample_id	local_sample_id	Group	Timepoint	Sex
SA263115	90266015509	Control	8 weeks of training or control time	Female
SA263116	90245015509	Control	8 weeks of training or control time	Female
SA263117	90248015509	Control	8 weeks of training or control time	Female
SA263118	90265015509	Control	8 weeks of training or control time	Female
SA263119	90252015509	Control	8 weeks of training or control time	Female
SA263120	90217015509	Control	8 weeks of training or control time	Male
SA263121	90229015509	Control	8 weeks of training or control time	Male
SA263122	90237015509	Control	8 weeks of training or control time	Male
SA263123	90232015509	Control	8 weeks of training or control time	Male
SA263124	90239015509	Control	8 weeks of training or control time	Male
SA263125	CS00000SB-04	QC-Blank	0 hour	-
SA263126	CS00000SB-05	QC-Blank	0 hour	-
SA263127	CS00000SB-03	QC-Blank	0 hour	-
SA263128	CS00000SB-02	QC-Blank	0 hour	-
SA263129	CS00000PB-01	QC-Blank	0 hour	-
SA263130	CS00000PB-04	QC-Blank	0 hour	-
SA263131	CS00000PB-02	QC-Blank	0 hour	-
SA263132	CS00000PB-03	QC-Blank	0 hour	-
SA263133	CS00000MP-04	QC-DriftCorrection	0 hour	-
SA263134	CS00000MP-02	QC-DriftCorrection	0 hour	-
SA263135	CS00000MP-05	QC-DriftCorrection	0 hour	-
SA263136	CS00000MP-03	QC-DriftCorrection	0 hour	-
SA263137	CS00000MP-08	QC-DriftCorrection	0 hour	-
SA263138	CS00000MP-01	QC-DriftCorrection	0 hour	-
SA263139	CS00000MP-09	QC-DriftCorrection	0 hour	-
SA263140	CS00000MP-07	QC-DriftCorrection	0 hour	-
SA263141	CS00000MP-06	QC-DriftCorrection	0 hour	-
SA263142	CS0000OP0-03	QC-Pooled	0 hour	-
SA263143	CS0000OP0-05	QC-Pooled	0 hour	-
SA263144	CS0000OP0-04	QC-Pooled	0 hour	-
SA263145	CS0000OP0-02	QC-Pooled	0 hour	-
SA263146	CS0000OP0-01	QC-Pooled	0 hour	-
SA263147	CS0000OP0-06	QC-Pooled	0 hour	-
SA263148	CS0000OP0-07	QC-Pooled	0 hour	-
SA263149	CS000QCMP-03	QC-Pooled	0 hour	-
SA263150	CS000QCMP-02	QC-Pooled	0 hour	-
SA263151	CS000QCMP-01	QC-Pooled	0 hour	-
SA263152	CS000QCMP-04	QC-Pooled	0 hour	-
SA263153	CS0UMRG01-03	QC-ReCAS	0 hour	-
SA263154	CS0UMRG01-02	QC-ReCAS	0 hour	-
SA263155	CS0UMRG01-04	QC-ReCAS	0 hour	-
SA263156	CS0UMRG01-01	QC-ReCAS	0 hour	-
SA263157	CSMR80008-03	QC-Reference	0 hour	-
SA263158	CSMR80008-02	QC-Reference	0 hour	-
SA263159	CSMR80009-04	QC-Reference	0 hour	-
SA263160	CSMR80008-04	QC-Reference	0 hour	-
SA263161	CSMR80008-01	QC-Reference	0 hour	-
SA263162	CSMR80009-03	QC-Reference	0 hour	-
SA263163	CSMR80009-02	QC-Reference	0 hour	-
SA263164	CSMR80009-01	QC-Reference	0 hour	-
SA263165	90559015509	Training	1 week of training or control time	Female
SA263166	90560015509	Training	1 week of training or control time	Female
SA263167	90567015509	Training	1 week of training or control time	Female
SA263168	90571015509	Training	1 week of training or control time	Female
SA263169	90564015509	Training	1 week of training or control time	Female
SA263170	90426015509	Training	1 week of training or control time	Male
SA263171	90423015509	Training	1 week of training or control time	Male
SA263172	90430015509	Training	1 week of training or control time	Male
SA263173	90422015509	Training	1 week of training or control time	Male
SA263174	90421015509	Training	1 week of training or control time	Male
SA263175	90576015509	Training	2 weeks of training	Female
SA263176	90587015509	Training	2 weeks of training	Female
SA263177	90578015509	Training	2 weeks of training	Female
SA263178	90585015509	Training	2 weeks of training	Female
SA263179	90581015509	Training	2 weeks of training	Female
SA263180	90441015509	Training	2 weeks of training	Male
SA263181	90449015509	Training	2 weeks of training	Male
SA263182	90444015509	Training	2 weeks of training	Male
SA263183	90439015509	Training	2 weeks of training	Male
SA263184	90450015509	Training	2 weeks of training	Male
SA263185	90420015509	Training	4 weeks of training	Female
SA263186	90406015509	Training	4 weeks of training	Female
SA263187	90410015509	Training	4 weeks of training	Female
SA263188	90412015509	Training	4 weeks of training	Female
SA263189	90416015509	Training	4 weeks of training	Female
SA263190	90280015509	Training	4 weeks of training	Male
SA263191	90292015509	Training	4 weeks of training	Male
SA263192	90283015509	Training	4 weeks of training	Male
SA263193	90281015509	Training	4 weeks of training	Male
SA263194	90289015509	Training	4 weeks of training	Male
SA263195	90251015509	Training	8 weeks of training or control time	Female
SA263196	90259015509	Training	8 weeks of training or control time	Female
SA263197	90267015509	Training	8 weeks of training or control time	Female
SA263198	90258015509	Training	8 weeks of training or control time	Female
SA263199	90254015509	Training	8 weeks of training or control time	Female
SA263200	90227015509	Training	8 weeks of training or control time	Male
SA263201	90218015509	Training	8 weeks of training or control time	Male
SA263202	90222015509	Training	8 weeks of training or control time	Male
SA263203	90223015509	Training	8 weeks of training or control time	Male
SA263204	90225015509	Training	8 weeks of training or control time	Male

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Showing results 1 to 90 of 90