Summary of Study ST002652

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001020. The data can be accessed directly via it's Project DOI: 10.21228/M8V97D This work is supported by NIH grant, U2C- DK119886.

See: https://www.metabolomicsworkbench.org/about/howtocite.php

This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.

Study ID	ST002652
Study Title	MoTrPAC: Endurance exercise training study in young adult rats, Tissue:Heart - Untargeted Lipidomics, Reversed-Phase Positive
Study Summary	The goal of the endurance exercise training study in young adult rats (internal code: PASS1B-06) was to perform exercise training studies in adult (6 month) F344 rats, and from these rats collect as many tissues as feasible in order to provide high quality samples for detailed analysis by chemical analysis sites. Tissues were collected from 10-12 rats sedentary control rats concurrent with the collection of the 8-week training groups. The 8-week training group and controls were from the same cohort and same age at euthanasia (either 8). For the older age group, an additional set of controls (n=5-6) were collected with the 1-2 week training group. Rats were either sedentary or underwent an exercise training program. Rats were exercised on the rodent treadmill 5 days per week using a progressive training protocol designed to exercise the rats at approximately 70% of VO2max as outlined in the Table on the next page. Training was performed no earlier than 10:00 am and no later than 5:00 pm over 5 consecutive days per week. Training was initiated with the treadmill set at 70% of VO2 max (see tables) and 5 degrees grade for 20 minutes. The duration of exercise was increased by one minute each day until day 31 of training (start of week 7), when a duration of 50 min was reached. Speed and grade of each training session increased in larger increments due to treadmill parameters. The highest intensity and duration of training began on day 31. This intensity was maintained for the final 10 days of the protocol to ensure steady state had been achieved. If any rats were unable to perform at least 4 days of training per week they were removed from the study and euthanized. It is important to note that the starting treadmill speed varied depending on the sex and age of the rat. The initial and maximum speeds were based on VO2max measurements obtained during the pre-training testing of the compliant rats. Rats assigned to the control group followed a schedule similar to the training group. They were placed in one lane on the treadmill for 15 minutes/day, 5 days per week. The treadmill was set at 0 m/min at an incline that corresponded to the incline being used by the training group.
Institute	Georgia Institute of Technology
Department	Department of Chemistry and Biochemistry
Laboratory	Systems Mass Spectrometry Core (SyMSC)
Last Name	Facundo
First Name	Fernandez
Address	901 Atlantic Dr NW, Atlanta, GA 30332-0400
Email	facundo.fernandez@chemistry.gatech.edu
Phone	(404) 385-4432
Submit Date	2023-05-01
Raw Data Available	Yes
Raw Data File Type(s)	TBD
Analysis Type Detail	LC-MS
Release Date	2023-10-06
Release Version	1

Select appropriate tab below to view additional metadata details:

Factors:

Subject type: Mammal; Subject species: Rattus norvegicus (Factor headings shown in green)

mb_sample_id	local_sample_id	Group	Timepoint	Sex
SA263495	90245015808	Control	8 weeks of training or control time	Female
SA263496	90266015808	Control	8 weeks of training or control time	Female
SA263497	90252015808	Control	8 weeks of training or control time	Female
SA263498	90248015808	Control	8 weeks of training or control time	Female
SA263499	90265015808	Control	8 weeks of training or control time	Female
SA263500	90217015808	Control	8 weeks of training or control time	Male
SA263501	90237015808	Control	8 weeks of training or control time	Male
SA263502	90229015808	Control	8 weeks of training or control time	Male
SA263503	90232015808	Control	8 weeks of training or control time	Male
SA263504	90239015808	Control	8 weeks of training or control time	Male
SA263505	SampleBlank06	QC-Blank	0 hour	-
SA263506	SampleBlank05	QC-Blank	0 hour	-
SA263507	SampleBlank03	QC-Blank	0 hour	-
SA263508	SampleBlank01	QC-Blank	0 hour	-
SA263509	SampleBlank04	QC-Blank	0 hour	-
SA263510	SampleBlank02	QC-Blank	0 hour	-
SA263511	QC09	QC-Pooled	0 hour	-
SA263512	QC01	QC-Pooled	0 hour	-
SA263513	QC02	QC-Pooled	0 hour	-
SA263514	QC08	QC-Pooled	0 hour	-
SA263515	QC05	QC-Pooled	0 hour	-
SA263516	QC07	QC-Pooled	0 hour	-
SA263517	QC06	QC-Pooled	0 hour	-
SA263518	QC04	QC-Pooled	0 hour	-
SA263519	QC03	QC-Pooled	0 hour	-
SA263520	IPE_Reference_Heart	QC-Reference	0 hour	-
SA263521	SED_Reference_Heart	QC-Reference	0 hour	-
SA263522	IPE_Reference_Heart02	QC-Reference	0 hour	-
SA263523	SED_Reference_Heart02	QC-Reference	0 hour	-
SA263524	90560015808	Training	1 week of training or control time	Female
SA263525	90567015808	Training	1 week of training or control time	Female
SA263526	90571015808	Training	1 week of training or control time	Female
SA263527	90564015808	Training	1 week of training or control time	Female
SA263528	90559015808	Training	1 week of training or control time	Female
SA263529	90423015808	Training	1 week of training or control time	Male
SA263530	90422015808	Training	1 week of training or control time	Male
SA263531	90421015808	Training	1 week of training or control time	Male
SA263532	90430015808	Training	1 week of training or control time	Male
SA263533	90426015808	Training	1 week of training or control time	Male
SA263534	90585015808	Training	2 weeks of training	Female
SA263535	90581015808	Training	2 weeks of training	Female
SA263536	90578015808	Training	2 weeks of training	Female
SA263537	90587015808	Training	2 weeks of training	Female
SA263538	90576015808	Training	2 weeks of training	Female
SA263539	90444015808	Training	2 weeks of training	Male
SA263540	90450015808	Training	2 weeks of training	Male
SA263541	90441015808	Training	2 weeks of training	Male
SA263542	90439015808	Training	2 weeks of training	Male
SA263543	90449015808	Training	2 weeks of training	Male
SA263544	90416015808	Training	4 weeks of training	Female
SA263545	90412015808	Training	4 weeks of training	Female
SA263546	90410015808	Training	4 weeks of training	Female
SA263547	90406015808	Training	4 weeks of training	Female
SA263548	90420015808	Training	4 weeks of training	Female
SA263549	90289015808	Training	4 weeks of training	Male
SA263550	90281015808	Training	4 weeks of training	Male
SA263551	90283015808	Training	4 weeks of training	Male
SA263552	90280015808	Training	4 weeks of training	Male
SA263553	90292015808	Training	4 weeks of training	Male
SA263554	90251015808	Training	8 weeks of training or control time	Female
SA263555	90254015808	Training	8 weeks of training or control time	Female
SA263556	90267015808	Training	8 weeks of training or control time	Female
SA263557	90259015808	Training	8 weeks of training or control time	Female
SA263558	90258015808	Training	8 weeks of training or control time	Female
SA263559	90218015808	Training	8 weeks of training or control time	Male
SA263560	90225015808	Training	8 weeks of training or control time	Male
SA263561	90227015808	Training	8 weeks of training or control time	Male
SA263562	90222015808	Training	8 weeks of training or control time	Male
SA263563	90223015808	Training	8 weeks of training or control time	Male

Showing results 1 to 69 of 69

Showing results 1 to 69 of 69