Summary of Study ST002653

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001020. The data can be accessed directly via it's Project DOI: 10.21228/M8V97D This work is supported by NIH grant, U2C- DK119886.

See: https://www.metabolomicsworkbench.org/about/howtocite.php

This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.

Study ID	ST002653
Study Title	MoTrPAC: Endurance exercise training study in young adult rats, Tissue:Heart - Untargeted Reversed-Phase Positive
Study Summary	The goal of the endurance exercise training study in young adult rats (internal code: PASS1B-06) was to perform exercise training studies in adult (6 month) F344 rats, and from these rats collect as many tissues as feasible in order to provide high quality samples for detailed analysis by chemical analysis sites. Tissues were collected from 10-12 rats sedentary control rats concurrent with the collection of the 8-week training groups. The 8-week training group and controls were from the same cohort and same age at euthanasia (either 8). For the older age group, an additional set of controls (n=5-6) were collected with the 1-2 week training group. Rats were either sedentary or underwent an exercise training program. Rats were exercised on the rodent treadmill 5 days per week using a progressive training protocol designed to exercise the rats at approximately 70% of VO2max as outlined in the Table on the next page. Training was performed no earlier than 10:00 am and no later than 5:00 pm over 5 consecutive days per week. Training was initiated with the treadmill set at 70% of VO2 max (see tables) and 5 degrees grade for 20 minutes. The duration of exercise was increased by one minute each day until day 31 of training (start of week 7), when a duration of 50 min was reached. Speed and grade of each training session increased in larger increments due to treadmill parameters. The highest intensity and duration of training began on day 31. This intensity was maintained for the final 10 days of the protocol to ensure steady state had been achieved. If any rats were unable to perform at least 4 days of training per week they were removed from the study and euthanized. It is important to note that the starting treadmill speed varied depending on the sex and age of the rat. The initial and maximum speeds were based on VO2max measurements obtained during the pre-training testing of the compliant rats. Rats assigned to the control group followed a schedule similar to the training group. They were placed in one lane on the treadmill for 15 minutes/day, 5 days per week. The treadmill was set at 0 m/min at an incline that corresponded to the incline being used by the training group.
Institute	University of Michigan
Department	Biomedical Research Core Facilities
Laboratory	Metabolomics core
Last Name	Burant
First Name	Charles
Address	6120 Brehm Tower,1000 Wall St., Ann Arbor, MI, 48105-5714
Email	burantc@med.umich.edu
Phone	(734) 232-0842
Submit Date	2023-05-01
Num Groups	65
Total Subjects	50
Raw Data Available	Yes
Raw Data File Type(s)	TBD
Analysis Type Detail	LC-MS
Release Date	2023-10-06
Release Version	1

Select appropriate tab below to view additional metadata details:

Factors:

Subject type: Mammal; Subject species: Rattus norvegicus (Factor headings shown in green)

mb_sample_id	local_sample_id	Group	Timepoint	Sex
SA263564	90245015807	Control	8 weeks of training or control time	Female
SA263565	90248015807	Control	8 weeks of training or control time	Female
SA263566	90252015807	Control	8 weeks of training or control time	Female
SA263567	90265015807	Control	8 weeks of training or control time	Female
SA263568	90266015807	Control	8 weeks of training or control time	Female
SA263569	90229015807	Control	8 weeks of training or control time	Male
SA263570	90237015807	Control	8 weeks of training or control time	Male
SA263571	90239015807	Control	8 weeks of training or control time	Male
SA263572	90217015807	Control	8 weeks of training or control time	Male
SA263573	90232015807	Control	8 weeks of training or control time	Male
SA263574	CS00000PB-2	QC-Blank	0 hour	-	-
SA263575	CS00000PB-4	QC-Blank	0 hour	-	-
SA263576	CS00000PB-1	QC-Blank	0 hour	-	-
SA263577	CS00000PB-3	QC-Blank	0 hour	-	-
SA263578	CS00000SB-5	QC-Blank	0 hour	-	-
SA263579	CS00000SB-2	QC-Blank	0 hour	-	-
SA263580	CS00000SB-1	QC-Blank	0 hour	-	-
SA263581	CS00000SB-3	QC-Blank	0 hour	-	-
SA263582	CS00000SB-4	QC-Blank	0 hour	-	-
SA263583	CS00000MP-3	QC-DriftCorrection	0 hour	-	-
SA263584	CS00000MP-9	QC-DriftCorrection	0 hour	-	-
SA263585	CS00000MP-5	QC-DriftCorrection	0 hour	-	-
SA263586	CS00000MP-4	QC-DriftCorrection	0 hour	-	-
SA263587	CS00000MP-6	QC-DriftCorrection	0 hour	-	-
SA263588	CS00000MP-7	QC-DriftCorrection	0 hour	-	-
SA263589	CS00000MP-8	QC-DriftCorrection	0 hour	-	-
SA263590	CS00000MP-2	QC-DriftCorrection	0 hour	-	-
SA263591	CS0000OP0-1	QC-Pooled	0 hour	-	-
SA263592	CS0000OP0-4	QC-Pooled	0 hour	-	-
SA263593	CS0000OP0-3	QC-Pooled	0 hour	-	-
SA263594	CS0000OP0-2	QC-Pooled	0 hour	-	-
SA263595	CS000QCMP-2	QC-Pooled	0 hour	-	-
SA263596	CS0000OP0-6	QC-Pooled	0 hour	-	-
SA263597	CS0000OP0-7	QC-Pooled	0 hour	-	-
SA263598	CS000QCMP-1	QC-Pooled	0 hour	-	-
SA263599	CS0000OP0-5	QC-Pooled	0 hour	-	-
SA263600	CS000QCMP-3	QC-Pooled	0 hour	-	-
SA263601	CS000QCMP-4	QC-Pooled	0 hour	-	-
SA263602	CS0UMRG01-1	QC-ReCAS	0 hour	-	-
SA263603	CS0UMRG01-2	QC-ReCAS	0 hour	-	-
SA263604	CSMR80022-1	QC-Reference	0 hour	-	-
SA263605	CSMR80022-2	QC-Reference	0 hour	-	-
SA263606	CSMR80022-3	QC-Reference	0 hour	-	-
SA263607	CSMR80023-3	QC-Reference	0 hour	-	-
SA263608	CSMR80023-2	QC-Reference	0 hour	-	-
SA263609	CSMR80023-1	QC-Reference	0 hour	-	-
SA263610	90559015807	Training	1 week of training or control time	Female
SA263611	90571015807	Training	1 week of training or control time	Female
SA263612	90564015807	Training	1 week of training or control time	Female
SA263613	90567015807	Training	1 week of training or control time	Female
SA263614	90560015807	Training	1 week of training or control time	Female
SA263615	90430015807	Training	1 week of training or control time	Male
SA263616	90421015807	Training	1 week of training or control time	Male
SA263617	90423015807	Training	1 week of training or control time	Male
SA263618	90426015807	Training	1 week of training or control time	Male
SA263619	90422015807	Training	1 week of training or control time	Male
SA263620	90576015807	Training	2 weeks of training	Female
SA263621	90587015807	Training	2 weeks of training	Female
SA263622	90578015807	Training	2 weeks of training	Female
SA263623	90581015807	Training	2 weeks of training	Female
SA263624	90585015807	Training	2 weeks of training	Female
SA263625	90449015807	Training	2 weeks of training	Male
SA263626	90450015807	Training	2 weeks of training	Male
SA263627	90444015807	Training	2 weeks of training	Male
SA263628	90441015807	Training	2 weeks of training	Male
SA263629	90439015807	Training	2 weeks of training	Male
SA263630	90412015807	Training	4 weeks of training	Female
SA263631	90420015807	Training	4 weeks of training	Female
SA263632	90406015807	Training	4 weeks of training	Female
SA263633	90410015807	Training	4 weeks of training	Female
SA263634	90416015807	Training	4 weeks of training	Female
SA263635	90280015807	Training	4 weeks of training	Male
SA263636	90281015807	Training	4 weeks of training	Male
SA263637	90292015807	Training	4 weeks of training	Male
SA263638	90289015807	Training	4 weeks of training	Male
SA263639	90283015807	Training	4 weeks of training	Male
SA263640	90251015807	Training	8 weeks of training or control time	Female
SA263641	90267015807	Training	8 weeks of training or control time	Female
SA263642	90254015807	Training	8 weeks of training or control time	Female
SA263643	90258015807	Training	8 weeks of training or control time	Female
SA263644	90259015807	Training	8 weeks of training or control time	Female
SA263645	90218015807	Training	8 weeks of training or control time	Male
SA263646	90222015807	Training	8 weeks of training or control time	Male
SA263647	90227015807	Training	8 weeks of training or control time	Male
SA263648	90225015807	Training	8 weeks of training or control time	Male
SA263649	90223015807	Training	8 weeks of training or control time	Male

Showing results 1 to 86 of 86

Showing results 1 to 86 of 86