Summary of Study ST002656

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001020. The data can be accessed directly via it's Project DOI: 10.21228/M8V97D This work is supported by NIH grant, U2C- DK119886.

See: https://www.metabolomicsworkbench.org/about/howtocite.php

This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.

Study ID	ST002656
Study Title	MoTrPAC: Endurance exercise training study in young adult rats, Tissue:Kidney - Untargeted Lipidomics, Reversed-Phase Negative
Study Summary	The goal of the endurance exercise training study in young adult rats (internal code: PASS1B-06) was to perform exercise training studies in adult (6 month) F344 rats, and from these rats collect as many tissues as feasible in order to provide high quality samples for detailed analysis by chemical analysis sites. Tissues were collected from 10-12 rats sedentary control rats concurrent with the collection of the 8-week training groups. The 8-week training group and controls were from the same cohort and same age at euthanasia (either 8). For the older age group, an additional set of controls (n=5-6) were collected with the 1-2 week training group. Rats were either sedentary or underwent an exercise training program. Rats were exercised on the rodent treadmill 5 days per week using a progressive training protocol designed to exercise the rats at approximately 70% of VO2max as outlined in the Table on the next page. Training was performed no earlier than 10:00 am and no later than 5:00 pm over 5 consecutive days per week. Training was initiated with the treadmill set at 70% of VO2 max (see tables) and 5 degrees grade for 20 minutes. The duration of exercise was increased by one minute each day until day 31 of training (start of week 7), when a duration of 50 min was reached. Speed and grade of each training session increased in larger increments due to treadmill parameters. The highest intensity and duration of training began on day 31. This intensity was maintained for the final 10 days of the protocol to ensure steady state had been achieved. If any rats were unable to perform at least 4 days of training per week they were removed from the study and euthanized. It is important to note that the starting treadmill speed varied depending on the sex and age of the rat. The initial and maximum speeds were based on VO2max measurements obtained during the pre-training testing of the compliant rats. Rats assigned to the control group followed a schedule similar to the training group. They were placed in one lane on the treadmill for 15 minutes/day, 5 days per week. The treadmill was set at 0 m/min at an incline that corresponded to the incline being used by the training group.
Institute	Georgia Institute of Technology
Department	Department of Chemistry and Biochemistry
Laboratory	Systems Mass Spectrometry Core (SyMSC)
Last Name	Facundo
First Name	Fernandez
Address	901 Atlantic Dr NW, Atlanta, GA 30332-0400
Email	facundo.fernandez@chemistry.gatech.edu
Phone	(404) 385-4432
Submit Date	2023-05-01
Raw Data Available	Yes
Raw Data File Type(s)	TBD
Analysis Type Detail	LC-MS
Release Date	2023-10-06
Release Version	1

Select appropriate tab below to view additional metadata details:

Factors:

Subject type: Mammal; Subject species: Rattus norvegicus (Factor headings shown in green)

mb_sample_id	local_sample_id	Group	Timepoint	Sex
SA263806	90248015907	Control	8 weeks of training or control time	Female
SA263807	90266015907	Control	8 weeks of training or control time	Female
SA263808	90265015907	Control	8 weeks of training or control time	Female
SA263809	90245015907	Control	8 weeks of training or control time	Female
SA263810	90252015907	Control	8 weeks of training or control time	Female
SA263811	90229015907	Control	8 weeks of training or control time	Male
SA263812	90217015907	Control	8 weeks of training or control time	Male
SA263813	90237015907	Control	8 weeks of training or control time	Male
SA263814	90239015907	Control	8 weeks of training or control time	Male
SA263815	90232015907	Control	8 weeks of training or control time	Male
SA263816	SampleBlank03	QC-Blank	0 hour	-
SA263817	SampleBlank05	QC-Blank	0 hour	-
SA263818	SampleBlank01	QC-Blank	0 hour	-
SA263819	SampleBlank04	QC-Blank	0 hour	-
SA263820	SampleBlank06	QC-Blank	0 hour	-
SA263821	SampleBlank02	QC-Blank	0 hour	-
SA263822	QC05	QC-Pooled	0 hour	-
SA263823	QC04	QC-Pooled	0 hour	-
SA263824	QC01	QC-Pooled	0 hour	-
SA263825	QC03	QC-Pooled	0 hour	-
SA263826	QC02	QC-Pooled	0 hour	-
SA263827	QC09	QC-Pooled	0 hour	-
SA263828	QC07	QC-Pooled	0 hour	-
SA263829	QC06	QC-Pooled	0 hour	-
SA263830	QC08	QC-Pooled	0 hour	-
SA263831	SED_Reference_Kidney	QC-Reference	0 hour	-
SA263832	IPE_Reference_Kidney02	QC-Reference	0 hour	-
SA263833	IPE_Reference_Kidney	QC-Reference	0 hour	-
SA263834	SED_Reference_Kidney02	QC-Reference	0 hour	-
SA263835	90571015907	Training	1 week of training or control time	Female
SA263836	90564015907	Training	1 week of training or control time	Female
SA263837	90559015907	Training	1 week of training or control time	Female
SA263838	90567015907	Training	1 week of training or control time	Female
SA263839	90560015907	Training	1 week of training or control time	Female
SA263840	90430015907	Training	1 week of training or control time	Male
SA263841	90426015907	Training	1 week of training or control time	Male
SA263842	90422015907	Training	1 week of training or control time	Male
SA263843	90421015907	Training	1 week of training or control time	Male
SA263844	90423015907	Training	1 week of training or control time	Male
SA263845	90585015907	Training	2 weeks of training	Female
SA263846	90587015907	Training	2 weeks of training	Female
SA263847	90576015907	Training	2 weeks of training	Female
SA263848	90578015907	Training	2 weeks of training	Female
SA263849	90581015907	Training	2 weeks of training	Female
SA263850	90439015907	Training	2 weeks of training	Male
SA263851	90441015907	Training	2 weeks of training	Male
SA263852	90444015907	Training	2 weeks of training	Male
SA263853	90449015907	Training	2 weeks of training	Male
SA263854	90450015907	Training	2 weeks of training	Male
SA263855	90416015907	Training	4 weeks of training	Female
SA263856	90412015907	Training	4 weeks of training	Female
SA263857	90410015907	Training	4 weeks of training	Female
SA263858	90406015907	Training	4 weeks of training	Female
SA263859	90420015907	Training	4 weeks of training	Female
SA263860	90283015907	Training	4 weeks of training	Male
SA263861	90281015907	Training	4 weeks of training	Male
SA263862	90292015907	Training	4 weeks of training	Male
SA263863	90289015907	Training	4 weeks of training	Male
SA263864	90280015907	Training	4 weeks of training	Male
SA263865	90254015907	Training	8 weeks of training or control time	Female
SA263866	90259015907	Training	8 weeks of training or control time	Female
SA263867	90251015907	Training	8 weeks of training or control time	Female
SA263868	90267015907	Training	8 weeks of training or control time	Female
SA263869	90258015907	Training	8 weeks of training or control time	Female
SA263870	90227015907	Training	8 weeks of training or control time	Male
SA263871	90223015907	Training	8 weeks of training or control time	Male
SA263872	90218015907	Training	8 weeks of training or control time	Male
SA263873	90225015907	Training	8 weeks of training or control time	Male
SA263874	90222015907	Training	8 weeks of training or control time	Male

Showing results 1 to 69 of 69

Showing results 1 to 69 of 69