Summary of Study ST002663

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001020. The data can be accessed directly via it's Project DOI: 10.21228/M8V97D This work is supported by NIH grant, U2C- DK119886.

See: https://www.metabolomicsworkbench.org/about/howtocite.php

This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.

Study ID	ST002663
Study Title	MoTrPAC: Endurance exercise training study in young adult rats, Tissue:White Adipose - Targeted Acyl-CoA
Study Summary	The goal of the endurance exercise training study in young adult rats (internal code: PASS1B-06) was to perform exercise training studies in adult (6 month) F344 rats, and from these rats collect as many tissues as feasible in order to provide high quality samples for detailed analysis by chemical analysis sites. Tissues were collected from 10-12 rats sedentary control rats concurrent with the collection of the 8-week training groups. The 8-week training group and controls were from the same cohort and same age at euthanasia (either 8). For the older age group, an additional set of controls (n=5-6) were collected with the 1-2 week training group. Rats were either sedentary or underwent an exercise training program. Rats were exercised on the rodent treadmill 5 days per week using a progressive training protocol designed to exercise the rats at approximately 70% of VO2max as outlined in the Table on the next page. Training was performed no earlier than 10:00 am and no later than 5:00 pm over 5 consecutive days per week. Training was initiated with the treadmill set at 70% of VO2 max (see tables) and 5 degrees grade for 20 minutes. The duration of exercise was increased by one minute each day until day 31 of training (start of week 7), when a duration of 50 min was reached. Speed and grade of each training session increased in larger increments due to treadmill parameters. The highest intensity and duration of training began on day 31. This intensity was maintained for the final 10 days of the protocol to ensure steady state had been achieved. If any rats were unable to perform at least 4 days of training per week they were removed from the study and euthanized. It is important to note that the starting treadmill speed varied depending on the sex and age of the rat. The initial and maximum speeds were based on VO2max measurements obtained during the pre-training testing of the compliant rats. Rats assigned to the control group followed a schedule similar to the training group. They were placed in one lane on the treadmill for 15 minutes/day, 5 days per week. The treadmill was set at 0 m/min at an incline that corresponded to the incline being used by the training group.
Institute	Duke University
Department	Duke Molecular Physiology Institute
Laboratory	Metabolomics Core Laboratory
Last Name	Newgard
First Name	Christopher
Address	300 N Duke St, Durham, NC 27701
Email	chris.newgard@duke.edu
Phone	(919) 668-6059
Submit Date	2023-04-25
Raw Data Available	Yes
Raw Data File Type(s)	TBD
Analysis Type Detail	LC-MS
Release Date	2023-10-06
Release Version	1

Select appropriate tab below to view additional metadata details:

Factors:

Subject type: Mammal; Subject species: Rattus norvegicus (Factor headings shown in green)

mb_sample_id	local_sample_id	Group	Timepoint	Sex
SA264276	90266017012	Control	8 weeks of training or control time	Female
SA264277	90245017012	Control	8 weeks of training or control time	Female
SA264278	90252017012	Control	8 weeks of training or control time	Female
SA264279	90265017012	Control	8 weeks of training or control time	Female
SA264280	90248017012	Control	8 weeks of training or control time	Female
SA264281	90217017012	Control	8 weeks of training or control time	Male
SA264282	90232017012	Control	8 weeks of training or control time	Male
SA264283	90239017012	Control	8 weeks of training or control time	Male
SA264284	90237017012	Control	8 weeks of training or control time	Male
SA264285	90229017012	Control	8 weeks of training or control time	Male
SA264286	80013827002_1	QC-ExternalStandard	0 hour	-
SA264287	80012817002_3	QC-ExternalStandard	0 hour	-
SA264288	80012817002_2	QC-ExternalStandard	0 hour	-
SA264289	80013827002_2	QC-ExternalStandard	0 hour	-
SA264290	80013827002_3	QC-ExternalStandard	0 hour	-
SA264291	80013827002_4	QC-ExternalStandard	0 hour	-
SA264292	80012817002_4	QC-ExternalStandard	0 hour	-
SA264293	80012817002_1	QC-ExternalStandard	0 hour	-
SA264294	90564017012	Training	1 week of training or control time	Female
SA264295	90559017012	Training	1 week of training or control time	Female
SA264296	90567017012	Training	1 week of training or control time	Female
SA264297	90571017012	Training	1 week of training or control time	Female
SA264298	90560017012	Training	1 week of training or control time	Female
SA264299	90423017012	Training	1 week of training or control time	Male
SA264300	90426017012	Training	1 week of training or control time	Male
SA264301	90421017012	Training	1 week of training or control time	Male
SA264302	90430017012	Training	1 week of training or control time	Male
SA264303	90422017012	Training	1 week of training or control time	Male
SA264304	90576017012	Training	2 weeks of training	Female
SA264305	90578017012	Training	2 weeks of training	Female
SA264306	90585017012	Training	2 weeks of training	Female
SA264307	90587017012	Training	2 weeks of training	Female
SA264308	90581017012	Training	2 weeks of training	Female
SA264309	90439017012	Training	2 weeks of training	Male
SA264310	90450017012	Training	2 weeks of training	Male
SA264311	90441017012	Training	2 weeks of training	Male
SA264312	90444017012	Training	2 weeks of training	Male
SA264313	90449017012	Training	2 weeks of training	Male
SA264314	90416017012	Training	4 weeks of training	Female
SA264315	90412017012	Training	4 weeks of training	Female
SA264316	90420017012	Training	4 weeks of training	Female
SA264317	90410017012	Training	4 weeks of training	Female
SA264318	90283017012	Training	4 weeks of training	Male
SA264319	90281017012	Training	4 weeks of training	Male
SA264320	90289017012	Training	4 weeks of training	Male
SA264321	90280017012	Training	4 weeks of training	Male
SA264322	90292017012	Training	4 weeks of training	Male
SA264323	90259017012	Training	8 weeks of training or control time	Female
SA264324	90254017012	Training	8 weeks of training or control time	Female
SA264325	90267017012	Training	8 weeks of training or control time	Female
SA264326	90251017012	Training	8 weeks of training or control time	Female
SA264327	90223017012	Training	8 weeks of training or control time	Male
SA264328	90218017012	Training	8 weeks of training or control time	Male
SA264329	90222017012	Training	8 weeks of training or control time	Male
SA264330	90225017012	Training	8 weeks of training or control time	Male

Showing results 1 to 55 of 55

Showing results 1 to 55 of 55