Summary of Study ST002671

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001020. The data can be accessed directly via it's Project DOI: 10.21228/M8V97D This work is supported by NIH grant, U2C- DK119886.

See: https://www.metabolomicsworkbench.org/about/howtocite.php

This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.

Study ID	ST002671
Study Title	MoTrPAC: Endurance exercise training study in young adult rats, Tissue:Lung - Untargeted Lipidomics, Reversed-Phase Positive
Study Summary	The goal of the endurance exercise training study in young adult rats (internal code: PASS1B-06) was to perform exercise training studies in adult (6 month) F344 rats, and from these rats collect as many tissues as feasible in order to provide high quality samples for detailed analysis by chemical analysis sites. Tissues were collected from 10-12 rats sedentary control rats concurrent with the collection of the 8-week training groups. The 8-week training group and controls were from the same cohort and same age at euthanasia (either 8). For the older age group, an additional set of controls (n=5-6) were collected with the 1-2 week training group. Rats were either sedentary or underwent an exercise training program. Rats were exercised on the rodent treadmill 5 days per week using a progressive training protocol designed to exercise the rats at approximately 70% of VO2max as outlined in the Table on the next page. Training was performed no earlier than 10:00 am and no later than 5:00 pm over 5 consecutive days per week. Training was initiated with the treadmill set at 70% of VO2 max (see tables) and 5 degrees grade for 20 minutes. The duration of exercise was increased by one minute each day until day 31 of training (start of week 7), when a duration of 50 min was reached. Speed and grade of each training session increased in larger increments due to treadmill parameters. The highest intensity and duration of training began on day 31. This intensity was maintained for the final 10 days of the protocol to ensure steady state had been achieved. If any rats were unable to perform at least 4 days of training per week they were removed from the study and euthanized. It is important to note that the starting treadmill speed varied depending on the sex and age of the rat. The initial and maximum speeds were based on VO2max measurements obtained during the pre-training testing of the compliant rats. Rats assigned to the control group followed a schedule similar to the training group. They were placed in one lane on the treadmill for 15 minutes/day, 5 days per week. The treadmill was set at 0 m/min at an incline that corresponded to the incline being used by the training group.
Institute	Georgia Institute of Technology
Department	Department of Chemistry and Biochemistry
Laboratory	Systems Mass Spectrometry Core (SyMSC)
Last Name	Facundo
First Name	Fernandez
Address	901 Atlantic Dr NW, Atlanta, GA 30332-0400
Email	facundo.fernandez@chemistry.gatech.edu
Phone	(404) 385-4432
Submit Date	2023-05-02
Raw Data Available	Yes
Raw Data File Type(s)	TBD
Analysis Type Detail	LC-MS
Release Date	2023-10-06
Release Version	1

Select appropriate tab below to view additional metadata details:

Factors:

Subject type: Mammal; Subject species: Rattus norvegicus (Factor headings shown in green)

mb_sample_id	local_sample_id	Group	Timepoint	Sex
SA264759	90265016607	Control	8 weeks of training or control time	Female
SA264760	90245016607	Control	8 weeks of training or control time	Female
SA264761	90248016607	Control	8 weeks of training or control time	Female
SA264762	90266016607	Control	8 weeks of training or control time	Female
SA264763	90252016607	Control	8 weeks of training or control time	Female
SA264764	90239016607	Control	8 weeks of training or control time	Male
SA264765	90229016607	Control	8 weeks of training or control time	Male
SA264766	90232016607	Control	8 weeks of training or control time	Male
SA264767	90217016607	Control	8 weeks of training or control time	Male
SA264768	90237016607	Control	8 weeks of training or control time	Male
SA264769	SampleBlank05	QC-Blank	0 hour	-
SA264770	SampleBlank03	QC-Blank	0 hour	-
SA264771	SampleBlank01	QC-Blank	0 hour	-
SA264772	SampleBlank04	QC-Blank	0 hour	-
SA264773	SampleBlank06	QC-Blank	0 hour	-
SA264774	SampleBlank02	QC-Blank	0 hour	-
SA264775	QC06	QC-Pooled	0 hour	-
SA264776	QC08	QC-Pooled	0 hour	-
SA264777	QC07	QC-Pooled	0 hour	-
SA264778	QC05	QC-Pooled	0 hour	-
SA264779	QC02	QC-Pooled	0 hour	-
SA264780	QC09	QC-Pooled	0 hour	-
SA264781	QC04	QC-Pooled	0 hour	-
SA264782	QC01	QC-Pooled	0 hour	-
SA264783	QC03	QC-Pooled	0 hour	-
SA264784	SED_Reference_Lung02	QC-Reference	0 hour	-
SA264785	SED_Reference_Lung	QC-Reference	0 hour	-
SA264786	IPE_Reference_Lung	QC-Reference	0 hour	-
SA264787	IPE_Reference_Lung02	QC-Reference	0 hour	-
SA264788	90560016607	Training	1 week of training or control time	Female
SA264789	90559016607	Training	1 week of training or control time	Female
SA264790	90571016607	Training	1 week of training or control time	Female
SA264791	90567016607	Training	1 week of training or control time	Female
SA264792	90564016607	Training	1 week of training or control time	Female
SA264793	90422016607	Training	1 week of training or control time	Male
SA264794	90421016607	Training	1 week of training or control time	Male
SA264795	90423016607	Training	1 week of training or control time	Male
SA264796	90426016607	Training	1 week of training or control time	Male
SA264797	90430016607	Training	1 week of training or control time	Male
SA264798	90576016607	Training	2 weeks of training	Female
SA264799	90581016607	Training	2 weeks of training	Female
SA264800	90578016607	Training	2 weeks of training	Female
SA264801	90587016607	Training	2 weeks of training	Female
SA264802	90585016607	Training	2 weeks of training	Female
SA264803	90450016607	Training	2 weeks of training	Male
SA264804	90439016607	Training	2 weeks of training	Male
SA264805	90444016607	Training	2 weeks of training	Male
SA264806	90441016607	Training	2 weeks of training	Male
SA264807	90449016607	Training	2 weeks of training	Male
SA264808	90406016607	Training	4 weeks of training	Female
SA264809	90416016607	Training	4 weeks of training	Female
SA264810	90412016607	Training	4 weeks of training	Female
SA264811	90420016607	Training	4 weeks of training	Female
SA264812	90410016607	Training	4 weeks of training	Female
SA264813	90289016607	Training	4 weeks of training	Male
SA264814	90292016607	Training	4 weeks of training	Male
SA264815	90280016607	Training	4 weeks of training	Male
SA264816	90283016607	Training	4 weeks of training	Male
SA264817	90281016607	Training	4 weeks of training	Male
SA264818	90259016607	Training	8 weeks of training or control time	Female
SA264819	90251016607	Training	8 weeks of training or control time	Female
SA264820	90267016607	Training	8 weeks of training or control time	Female
SA264821	90258016607	Training	8 weeks of training or control time	Female
SA264822	90254016607	Training	8 weeks of training or control time	Female
SA264823	90223016607	Training	8 weeks of training or control time	Male
SA264824	90218016607	Training	8 weeks of training or control time	Male
SA264825	90227016607	Training	8 weeks of training or control time	Male
SA264826	90225016607	Training	8 weeks of training or control time	Male
SA264827	90222016607	Training	8 weeks of training or control time	Male

Showing results 1 to 69 of 69

Showing results 1 to 69 of 69