Summary of Study ST002672

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001020. The data can be accessed directly via it's Project DOI: 10.21228/M8V97D This work is supported by NIH grant, U2C- DK119886.

See: https://www.metabolomicsworkbench.org/about/howtocite.php

This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.

Study ID	ST002672
Study Title	MoTrPAC: Endurance exercise training study in young adult rats, Tissue:Lung - Untargeted Reversed-Phase Negative
Study Summary	The goal of the endurance exercise training study in young adult rats (internal code: PASS1B-06) was to perform exercise training studies in adult (6 month) F344 rats, and from these rats collect as many tissues as feasible in order to provide high quality samples for detailed analysis by chemical analysis sites. Tissues were collected from 10-12 rats sedentary control rats concurrent with the collection of the 8-week training groups. The 8-week training group and controls were from the same cohort and same age at euthanasia (either 8). For the older age group, an additional set of controls (n=5-6) were collected with the 1-2 week training group. Rats were either sedentary or underwent an exercise training program. Rats were exercised on the rodent treadmill 5 days per week using a progressive training protocol designed to exercise the rats at approximately 70% of VO2max as outlined in the Table on the next page. Training was performed no earlier than 10:00 am and no later than 5:00 pm over 5 consecutive days per week. Training was initiated with the treadmill set at 70% of VO2 max (see tables) and 5 degrees grade for 20 minutes. The duration of exercise was increased by one minute each day until day 31 of training (start of week 7), when a duration of 50 min was reached. Speed and grade of each training session increased in larger increments due to treadmill parameters. The highest intensity and duration of training began on day 31. This intensity was maintained for the final 10 days of the protocol to ensure steady state had been achieved. If any rats were unable to perform at least 4 days of training per week they were removed from the study and euthanized. It is important to note that the starting treadmill speed varied depending on the sex and age of the rat. The initial and maximum speeds were based on VO2max measurements obtained during the pre-training testing of the compliant rats. Rats assigned to the control group followed a schedule similar to the training group. They were placed in one lane on the treadmill for 15 minutes/day, 5 days per week. The treadmill was set at 0 m/min at an incline that corresponded to the incline being used by the training group.
Institute	University of Michigan
Department	Biomedical Research Core Facilities
Laboratory	Metabolomics core
Last Name	Burant
First Name	Charles
Address	6120 Brehm Tower,1000 Wall St., Ann Arbor, MI, 48105-5714
Email	burantc@med.umich.edu
Phone	(734) 232-0842
Submit Date	2023-05-02
Num Groups	65
Total Subjects	50
Raw Data Available	Yes
Raw Data File Type(s)	TBD
Analysis Type Detail	LC-MS
Release Date	2023-10-06
Release Version	1

Select appropriate tab below to view additional metadata details:

Factors:

Subject type: Mammal; Subject species: Rattus norvegicus (Factor headings shown in green)

mb_sample_id	local_sample_id	Group	Timepoint	Sex
SA264828	90266016606	Control	8 weeks of training or control time	Female
SA264829	90245016606	Control	8 weeks of training or control time	Female
SA264830	90248016606	Control	8 weeks of training or control time	Female
SA264831	90265016606	Control	8 weeks of training or control time	Female
SA264832	90252016606	Control	8 weeks of training or control time	Female
SA264833	90217016606	Control	8 weeks of training or control time	Male
SA264834	90229016606	Control	8 weeks of training or control time	Male
SA264835	90237016606	Control	8 weeks of training or control time	Male
SA264836	90232016606	Control	8 weeks of training or control time	Male
SA264837	90239016606	Control	8 weeks of training or control time	Male
SA264838	CS00000SB-03	QC-Blank	0 hour	-
SA264839	CS00000SB-05	QC-Blank	0 hour	-
SA264840	CS00000SB-04	QC-Blank	0 hour	-
SA264841	CS00000SB-02	QC-Blank	0 hour	-
SA264842	CS00000PB-01	QC-Blank	0 hour	-
SA264843	CS00000PB-04	QC-Blank	0 hour	-
SA264844	CS00000PB-02	QC-Blank	0 hour	-
SA264845	CS00000PB-03	QC-Blank	0 hour	-
SA264846	CS00000MP-04	QC-DriftCorrection	0 hour	-
SA264847	CS00000MP-05	QC-DriftCorrection	0 hour	-
SA264848	CS00000MP-02	QC-DriftCorrection	0 hour	-
SA264849	CS00000MP-06	QC-DriftCorrection	0 hour	-
SA264850	CS00000MP-03	QC-DriftCorrection	0 hour	-
SA264851	CS00000MP-09	QC-DriftCorrection	0 hour	-
SA264852	CS00000MP-7a	QC-DriftCorrection	0 hour	-
SA264853	CS00000MP-01	QC-DriftCorrection	0 hour	-
SA264854	CS00000MP-08	QC-DriftCorrection	0 hour	-
SA264855	CS00000MP-07	QC-DriftCorrection	0 hour	-
SA264856	CS0000OP0-02	QC-Pooled	0 hour	-
SA264857	CS0000OP0-05	QC-Pooled	0 hour	-
SA264858	CS0000OP0-04	QC-Pooled	0 hour	-
SA264859	CS0000OP0-03	QC-Pooled	0 hour	-
SA264860	CS0000OP0-01	QC-Pooled	0 hour	-
SA264861	CS0000OP0-06	QC-Pooled	0 hour	-
SA264862	CS0000OP0-07	QC-Pooled	0 hour	-
SA264863	CS000QCMP-03	QC-Pooled	0 hour	-
SA264864	CS000QCMP-02	QC-Pooled	0 hour	-
SA264865	CS000QCMP-01	QC-Pooled	0 hour	-
SA264866	CS000QCMP-04	QC-Pooled	0 hour	-
SA264867	CS0UMRG01-03	QC-ReCAS	0 hour	-
SA264868	CS0UMRG01-02	QC-ReCAS	0 hour	-
SA264869	CS0UMRG01-04	QC-ReCAS	0 hour	-
SA264870	CS0UMRG01-01	QC-ReCAS	0 hour	-
SA264871	CSMR80016-03	QC-Reference	0 hour	-
SA264872	CSMR80016-02	QC-Reference	0 hour	-
SA264873	CSMR80017-04	QC-Reference	0 hour	-
SA264874	CSMR80016-04	QC-Reference	0 hour	-
SA264875	CSMR80016-01	QC-Reference	0 hour	-
SA264876	CSMR80017-02	QC-Reference	0 hour	-
SA264877	CSMR80017-03	QC-Reference	0 hour	-
SA264878	CSMR80017-01	QC-Reference	0 hour	-
SA264879	90559016606	Training	1 week of training or control time	Female
SA264880	90560016606	Training	1 week of training or control time	Female
SA264881	90567016606	Training	1 week of training or control time	Female
SA264882	90571016606	Training	1 week of training or control time	Female
SA264883	90564016606	Training	1 week of training or control time	Female
SA264884	90426016606	Training	1 week of training or control time	Male
SA264885	90423016606	Training	1 week of training or control time	Male
SA264886	90430016606	Training	1 week of training or control time	Male
SA264887	90422016606	Training	1 week of training or control time	Male
SA264888	90421016606	Training	1 week of training or control time	Male
SA264889	90576016606	Training	2 weeks of training	Female
SA264890	90587016606	Training	2 weeks of training	Female
SA264891	90578016606	Training	2 weeks of training	Female
SA264892	90585016606	Training	2 weeks of training	Female
SA264893	90581016606	Training	2 weeks of training	Female
SA264894	90441016606	Training	2 weeks of training	Male
SA264895	90449016606	Training	2 weeks of training	Male
SA264896	90444016606	Training	2 weeks of training	Male
SA264897	90439016606	Training	2 weeks of training	Male
SA264898	90450016606	Training	2 weeks of training	Male
SA264899	90420016606	Training	4 weeks of training	Female
SA264900	90406016606	Training	4 weeks of training	Female
SA264901	90410016606	Training	4 weeks of training	Female
SA264902	90412016606	Training	4 weeks of training	Female
SA264903	90416016606	Training	4 weeks of training	Female
SA264904	90280016606	Training	4 weeks of training	Male
SA264905	90292016606	Training	4 weeks of training	Male
SA264906	90283016606	Training	4 weeks of training	Male
SA264907	90281016606	Training	4 weeks of training	Male
SA264908	90289016606	Training	4 weeks of training	Male
SA264909	90251016606	Training	8 weeks of training or control time	Female
SA264910	90259016606	Training	8 weeks of training or control time	Female
SA264911	90267016606	Training	8 weeks of training or control time	Female
SA264912	90258016606	Training	8 weeks of training or control time	Female
SA264913	90254016606	Training	8 weeks of training or control time	Female
SA264914	90225016606	Training	8 weeks of training or control time	Male
SA264915	90218016606	Training	8 weeks of training or control time	Male
SA264916	90222016606	Training	8 weeks of training or control time	Male
SA264917	90223016606	Training	8 weeks of training or control time	Male
SA264918	90227016606	Training	8 weeks of training or control time	Male

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Showing results 1 to 91 of 91