Summary of Study ST002676

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001020. The data can be accessed directly via it's Project DOI: 10.21228/M8V97D This work is supported by NIH grant, U2C- DK119886.

See: https://www.metabolomicsworkbench.org/about/howtocite.php

This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.

Study ID	ST002676
Study Title	MoTrPAC: Endurance exercise training study in young adult rats, Tissue:Liver - Untargeted Ion-Pair Negative
Study Summary	The goal of the endurance exercise training study in young adult rats (internal code: PASS1B-06) was to perform exercise training studies in adult (6 month) F344 rats, and from these rats collect as many tissues as feasible in order to provide high quality samples for detailed analysis by chemical analysis sites. Tissues were collected from 10-12 rats sedentary control rats concurrent with the collection of the 8-week training groups. The 8-week training group and controls were from the same cohort and same age at euthanasia (either 8). For the older age group, an additional set of controls (n=5-6) were collected with the 1-2 week training group. Rats were either sedentary or underwent an exercise training program. Rats were exercised on the rodent treadmill 5 days per week using a progressive training protocol designed to exercise the rats at approximately 70% of VO2max as outlined in the Table on the next page. Training was performed no earlier than 10:00 am and no later than 5:00 pm over 5 consecutive days per week. Training was initiated with the treadmill set at 70% of VO2 max (see tables) and 5 degrees grade for 20 minutes. The duration of exercise was increased by one minute each day until day 31 of training (start of week 7), when a duration of 50 min was reached. Speed and grade of each training session increased in larger increments due to treadmill parameters. The highest intensity and duration of training began on day 31. This intensity was maintained for the final 10 days of the protocol to ensure steady state had been achieved. If any rats were unable to perform at least 4 days of training per week they were removed from the study and euthanized. It is important to note that the starting treadmill speed varied depending on the sex and age of the rat. The initial and maximum speeds were based on VO2max measurements obtained during the pre-training testing of the compliant rats. Rats assigned to the control group followed a schedule similar to the training group. They were placed in one lane on the treadmill for 15 minutes/day, 5 days per week. The treadmill was set at 0 m/min at an incline that corresponded to the incline being used by the training group.
Institute	University of Michigan
Department	Biomedical Research Core Facilities
Laboratory	Metabolomics core
Last Name	Burant
First Name	Charles
Address	6120 Brehm Tower,1000 Wall St., Ann Arbor, MI, 48105-5714
Email	burantc@med.umich.edu
Phone	(734) 232-0842
Submit Date	2023-05-02
Num Groups	65
Total Subjects	50
Raw Data Available	Yes
Raw Data File Type(s)	TBD
Analysis Type Detail	LC-MS
Release Date	2023-10-06
Release Version	1

Select appropriate tab below to view additional metadata details:

Factors:

Subject type: Mammal; Subject species: Rattus norvegicus (Factor headings shown in green)

mb_sample_id	local_sample_id	Group	Timepoint	Sex
SA265141	90248016808	Control	8 weeks of training or control time	Female
SA265142	90265016808	Control	8 weeks of training or control time	Female
SA265143	90252016808	Control	8 weeks of training or control time	Female
SA265144	90266016808	Control	8 weeks of training or control time	Female
SA265145	90245016808	Control	8 weeks of training or control time	Female
SA265146	90217016808	Control	8 weeks of training or control time	Male
SA265147	90239016808	Control	8 weeks of training or control time	Male
SA265148	90229016808	Control	8 weeks of training or control time	Male
SA265149	90232016808	Control	8 weeks of training or control time	Male
SA265150	90237016808	Control	8 weeks of training or control time	Male
SA265151	CS00000SB-05	QC-Blank	0 hour	-
SA265152	CS00000SB-06	QC-Blank	0 hour	-
SA265153	CS00000SB-04	QC-Blank	0 hour	-
SA265154	CS00000PB-04	QC-Blank	0 hour	-
SA265155	CS00000SB-03	QC-Blank	0 hour	-
SA265156	CS00000PB-01	QC-Blank	0 hour	-
SA265157	CS00000PB-03	QC-Blank	0 hour	-
SA265158	CS00000PB-02	QC-Blank	0 hour	-
SA265159	CS00000SB-02	QC-Blank	0 hour	-
SA265160	CS000QCMP-02	QC-Pooled	0 hour	-
SA265161	CS000QCMP-03	QC-Pooled	0 hour	-
SA265162	CS00000MP-01	QC-Pooled	0 hour	-
SA265163	CS000QCMP-01	QC-Pooled	0 hour	-
SA265164	CS000QCMP-04	QC-Pooled	0 hour	-
SA265165	CS0000OP0-02	QC-Pooled	0 hour	-
SA265166	CS00000MP-06	QC-Pooled	0 hour	-
SA265167	CS00000MP-07	QC-Pooled	0 hour	-
SA265168	CS00000MP-05	QC-Pooled	0 hour	-
SA265169	CS00000MP-04	QC-Pooled	0 hour	-
SA265170	CS00000MP-02	QC-Pooled	0 hour	-
SA265171	CS00000MP-03	QC-Pooled	0 hour	-
SA265172	CS00000MP-08	QC-Pooled	0 hour	-
SA265173	CS00000MP-09	QC-Pooled	0 hour	-
SA265174	CS0000OP0-05	QC-Pooled	0 hour	-
SA265175	CS0000OP0-06	QC-Pooled	0 hour	-
SA265176	CS0000OP0-04	QC-Pooled	0 hour	-
SA265177	CS0000OP0-03	QC-Pooled	0 hour	-
SA265178	CS0000OP0-01	QC-Pooled	0 hour	-
SA265179	CS0000OP0-07	QC-Pooled	0 hour	-
SA265180	CS0UMRG01-03	QC-ReCAS	0 hour	-
SA265181	CS0UMRG01-02	QC-ReCAS	0 hour	-
SA265182	CS0UMRG01-04	QC-ReCAS	0 hour	-
SA265183	CS0UMRG01-01	QC-ReCAS	0 hour	-
SA265184	CSMR80010-03	QC-Reference	0 hour	-
SA265185	CSMR80010-02	QC-Reference	0 hour	-
SA265186	CSMR80011-04	QC-Reference	0 hour	-
SA265187	CSMR80010-04	QC-Reference	0 hour	-
SA265188	CSMR80010-01	QC-Reference	0 hour	-
SA265189	CSMR80011-02	QC-Reference	0 hour	-
SA265190	CSMR80011-03	QC-Reference	0 hour	-
SA265191	CSMR80011-01	QC-Reference	0 hour	-
SA265192	90559016808	Training	1 week of training or control time	Female
SA265193	90560016808	Training	1 week of training or control time	Female
SA265194	90567016808	Training	1 week of training or control time	Female
SA265195	90571016808	Training	1 week of training or control time	Female
SA265196	90564016808	Training	1 week of training or control time	Female
SA265197	90426016808	Training	1 week of training or control time	Male
SA265198	90423016808	Training	1 week of training or control time	Male
SA265199	90430016808	Training	1 week of training or control time	Male
SA265200	90422016808	Training	1 week of training or control time	Male
SA265201	90421016808	Training	1 week of training or control time	Male
SA265202	90576016808	Training	2 weeks of training	Female
SA265203	90587016808	Training	2 weeks of training	Female
SA265204	90578016808	Training	2 weeks of training	Female
SA265205	90585016808	Training	2 weeks of training	Female
SA265206	90581016808	Training	2 weeks of training	Female
SA265207	90441016808	Training	2 weeks of training	Male
SA265208	90449016808	Training	2 weeks of training	Male
SA265209	90444016808	Training	2 weeks of training	Male
SA265210	90439016808	Training	2 weeks of training	Male
SA265211	90450016808	Training	2 weeks of training	Male
SA265212	90420016808	Training	4 weeks of training	Female
SA265213	90406016808	Training	4 weeks of training	Female
SA265214	90410016808	Training	4 weeks of training	Female
SA265215	90412016808	Training	4 weeks of training	Female
SA265216	90416016808	Training	4 weeks of training	Female
SA265217	90280016808	Training	4 weeks of training	Male
SA265218	90292016808	Training	4 weeks of training	Male
SA265219	90283016808	Training	4 weeks of training	Male
SA265220	90281016808	Training	4 weeks of training	Male
SA265221	90289016808	Training	4 weeks of training	Male
SA265222	90251016808	Training	8 weeks of training or control time	Female
SA265223	90259016808	Training	8 weeks of training or control time	Female
SA265224	90267016808	Training	8 weeks of training or control time	Female
SA265225	90258016808	Training	8 weeks of training or control time	Female
SA265226	90254016808	Training	8 weeks of training or control time	Female
SA265227	90225016808	Training	8 weeks of training or control time	Male
SA265228	90218016808	Training	8 weeks of training or control time	Male
SA265229	90222016808	Training	8 weeks of training or control time	Male
SA265230	90223016808	Training	8 weeks of training or control time	Male
SA265231	90227016808	Training	8 weeks of training or control time	Male

Showing results 1 to 91 of 91

Showing results 1 to 91 of 91