Summary of Study ST002677

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001020. The data can be accessed directly via it's Project DOI: 10.21228/M8V97D This work is supported by NIH grant, U2C- DK119886.

See: https://www.metabolomicsworkbench.org/about/howtocite.php

This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.

Study ID	ST002677
Study Title	MoTrPAC: Endurance exercise training study in young adult rats, Tissue:Liver - Untargeted Lipidomics, Reversed-Phase Negative
Study Summary	The goal of the endurance exercise training study in young adult rats (internal code: PASS1B-06) was to perform exercise training studies in adult (6 month) F344 rats, and from these rats collect as many tissues as feasible in order to provide high quality samples for detailed analysis by chemical analysis sites. Tissues were collected from 10-12 rats sedentary control rats concurrent with the collection of the 8-week training groups. The 8-week training group and controls were from the same cohort and same age at euthanasia (either 8). For the older age group, an additional set of controls (n=5-6) were collected with the 1-2 week training group. Rats were either sedentary or underwent an exercise training program. Rats were exercised on the rodent treadmill 5 days per week using a progressive training protocol designed to exercise the rats at approximately 70% of VO2max as outlined in the Table on the next page. Training was performed no earlier than 10:00 am and no later than 5:00 pm over 5 consecutive days per week. Training was initiated with the treadmill set at 70% of VO2 max (see tables) and 5 degrees grade for 20 minutes. The duration of exercise was increased by one minute each day until day 31 of training (start of week 7), when a duration of 50 min was reached. Speed and grade of each training session increased in larger increments due to treadmill parameters. The highest intensity and duration of training began on day 31. This intensity was maintained for the final 10 days of the protocol to ensure steady state had been achieved. If any rats were unable to perform at least 4 days of training per week they were removed from the study and euthanized. It is important to note that the starting treadmill speed varied depending on the sex and age of the rat. The initial and maximum speeds were based on VO2max measurements obtained during the pre-training testing of the compliant rats. Rats assigned to the control group followed a schedule similar to the training group. They were placed in one lane on the treadmill for 15 minutes/day, 5 days per week. The treadmill was set at 0 m/min at an incline that corresponded to the incline being used by the training group.
Institute	Georgia Institute of Technology
Department	Department of Chemistry and Biochemistry
Laboratory	Systems Mass Spectrometry Core (SyMSC)
Last Name	Facundo
First Name	Fernandez
Address	901 Atlantic Dr NW, Atlanta, GA 30332-0400
Email	facundo.fernandez@chemistry.gatech.edu
Phone	(404) 385-4432
Submit Date	2023-05-02
Raw Data Available	Yes
Raw Data File Type(s)	TBD
Analysis Type Detail	LC-MS
Release Date	2023-10-06
Release Version	1

Select appropriate tab below to view additional metadata details:

Factors:

Subject type: Mammal; Subject species: Rattus norvegicus (Factor headings shown in green)

mb_sample_id	local_sample_id	Group	Timepoint	Sex
SA265232	90266016809	Control	8 weeks of training or control time	Female
SA265233	90252016809	Control	8 weeks of training or control time	Female
SA265234	90265016809	Control	8 weeks of training or control time	Female
SA265235	90245016809	Control	8 weeks of training or control time	Female
SA265236	90248016809	Control	8 weeks of training or control time	Female
SA265237	90237016809	Control	8 weeks of training or control time	Male
SA265238	90217016809	Control	8 weeks of training or control time	Male
SA265239	90232016809	Control	8 weeks of training or control time	Male
SA265240	90229016809	Control	8 weeks of training or control time	Male
SA265241	90239016809	Control	8 weeks of training or control time	Male
SA265242	SampleBlank05	QC-Blank	0 hour	-
SA265243	SampleBlank04	QC-Blank	0 hour	-
SA265244	SampleBlank03	QC-Blank	0 hour	-
SA265245	SampleBlank06	QC-Blank	0 hour	-
SA265246	SampleBlank02	QC-Blank	0 hour	-
SA265247	SampleBlank01	QC-Blank	0 hour	-
SA265248	QC08	QC-Pooled	0 hour	-
SA265249	QC04	QC-Pooled	0 hour	-
SA265250	QC07	QC-Pooled	0 hour	-
SA265251	QC03	QC-Pooled	0 hour	-
SA265252	QC09	QC-Pooled	0 hour	-
SA265253	QC02	QC-Pooled	0 hour	-
SA265254	QC05	QC-Pooled	0 hour	-
SA265255	QC01	QC-Pooled	0 hour	-
SA265256	QC06	QC-Pooled	0 hour	-
SA265257	SED_Reference_Liver02	QC-Reference	0 hour	-
SA265258	IPE_Reference_Liver	QC-Reference	0 hour	-
SA265259	IPE_Reference_Liver02	QC-Reference	0 hour	-
SA265260	SED_Reference_Liver	QC-Reference	0 hour	-
SA265261	90567016809	Training	1 week of training or control time	Female
SA265262	90564016809	Training	1 week of training or control time	Female
SA265263	90560016809	Training	1 week of training or control time	Female
SA265264	90571016809	Training	1 week of training or control time	Female
SA265265	90559016809	Training	1 week of training or control time	Female
SA265266	90422016809	Training	1 week of training or control time	Male
SA265267	90430016809	Training	1 week of training or control time	Male
SA265268	90423016809	Training	1 week of training or control time	Male
SA265269	90426016809	Training	1 week of training or control time	Male
SA265270	90421016809	Training	1 week of training or control time	Male
SA265271	90578016809	Training	2 weeks of training	Female
SA265272	90585016809	Training	2 weeks of training	Female
SA265273	90581016809	Training	2 weeks of training	Female
SA265274	90576016809	Training	2 weeks of training	Female
SA265275	90587016809	Training	2 weeks of training	Female
SA265276	90441016809	Training	2 weeks of training	Male
SA265277	90439016809	Training	2 weeks of training	Male
SA265278	90450016809	Training	2 weeks of training	Male
SA265279	90444016809	Training	2 weeks of training	Male
SA265280	90449016809	Training	2 weeks of training	Male
SA265281	90410016809	Training	4 weeks of training	Female
SA265282	90412016809	Training	4 weeks of training	Female
SA265283	90416016809	Training	4 weeks of training	Female
SA265284	90406016809	Training	4 weeks of training	Female
SA265285	90420016809	Training	4 weeks of training	Female
SA265286	90292016809	Training	4 weeks of training	Male
SA265287	90283016809	Training	4 weeks of training	Male
SA265288	90280016809	Training	4 weeks of training	Male
SA265289	90281016809	Training	4 weeks of training	Male
SA265290	90289016809	Training	4 weeks of training	Male
SA265291	90251016809	Training	8 weeks of training or control time	Female
SA265292	90259016809	Training	8 weeks of training or control time	Female
SA265293	90267016809	Training	8 weeks of training or control time	Female
SA265294	90254016809	Training	8 weeks of training or control time	Female
SA265295	90258016809	Training	8 weeks of training or control time	Female
SA265296	90227016809	Training	8 weeks of training or control time	Male
SA265297	90225016809	Training	8 weeks of training or control time	Male
SA265298	90218016809	Training	8 weeks of training or control time	Male
SA265299	90223016809	Training	8 weeks of training or control time	Male
SA265300	90222016809	Training	8 weeks of training or control time	Male

Showing results 1 to 69 of 69

Showing results 1 to 69 of 69