Summary of Study ST002678

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001020. The data can be accessed directly via it's Project DOI: 10.21228/M8V97D This work is supported by NIH grant, U2C- DK119886.

See: https://www.metabolomicsworkbench.org/about/howtocite.php

This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.

Study ID	ST002678
Study Title	MoTrPAC: Endurance exercise training study in young adult rats, Tissue:Liver - Untargeted Lipidomics, Reversed-Phase Positive
Study Summary	The goal of the endurance exercise training study in young adult rats (internal code: PASS1B-06) was to perform exercise training studies in adult (6 month) F344 rats, and from these rats collect as many tissues as feasible in order to provide high quality samples for detailed analysis by chemical analysis sites. Tissues were collected from 10-12 rats sedentary control rats concurrent with the collection of the 8-week training groups. The 8-week training group and controls were from the same cohort and same age at euthanasia (either 8). For the older age group, an additional set of controls (n=5-6) were collected with the 1-2 week training group. Rats were either sedentary or underwent an exercise training program. Rats were exercised on the rodent treadmill 5 days per week using a progressive training protocol designed to exercise the rats at approximately 70% of VO2max as outlined in the Table on the next page. Training was performed no earlier than 10:00 am and no later than 5:00 pm over 5 consecutive days per week. Training was initiated with the treadmill set at 70% of VO2 max (see tables) and 5 degrees grade for 20 minutes. The duration of exercise was increased by one minute each day until day 31 of training (start of week 7), when a duration of 50 min was reached. Speed and grade of each training session increased in larger increments due to treadmill parameters. The highest intensity and duration of training began on day 31. This intensity was maintained for the final 10 days of the protocol to ensure steady state had been achieved. If any rats were unable to perform at least 4 days of training per week they were removed from the study and euthanized. It is important to note that the starting treadmill speed varied depending on the sex and age of the rat. The initial and maximum speeds were based on VO2max measurements obtained during the pre-training testing of the compliant rats. Rats assigned to the control group followed a schedule similar to the training group. They were placed in one lane on the treadmill for 15 minutes/day, 5 days per week. The treadmill was set at 0 m/min at an incline that corresponded to the incline being used by the training group.
Institute	Georgia Institute of Technology
Department	Department of Chemistry and Biochemistry
Laboratory	Systems Mass Spectrometry Core (SyMSC)
Last Name	Facundo
First Name	Fernandez
Address	901 Atlantic Dr NW, Atlanta, GA 30332-0400
Email	facundo.fernandez@chemistry.gatech.edu
Phone	(404) 385-4432
Submit Date	2023-05-02
Raw Data Available	Yes
Raw Data File Type(s)	TBD
Analysis Type Detail	LC-MS
Release Date	2023-10-06
Release Version	1

Select appropriate tab below to view additional metadata details:

Factors:

Subject type: Mammal; Subject species: Rattus norvegicus (Factor headings shown in green)

mb_sample_id	local_sample_id	Group	Timepoint	Sex
SA265301	90266016809	Control	8 weeks of training or control time	Female
SA265302	90252016809	Control	8 weeks of training or control time	Female
SA265303	90265016809	Control	8 weeks of training or control time	Female
SA265304	90245016809	Control	8 weeks of training or control time	Female
SA265305	90248016809	Control	8 weeks of training or control time	Female
SA265306	90237016809	Control	8 weeks of training or control time	Male
SA265307	90217016809	Control	8 weeks of training or control time	Male
SA265308	90232016809	Control	8 weeks of training or control time	Male
SA265309	90229016809	Control	8 weeks of training or control time	Male
SA265310	90239016809	Control	8 weeks of training or control time	Male
SA265311	SampleBlank05	QC-Blank	0 hour	-
SA265312	SampleBlank04	QC-Blank	0 hour	-
SA265313	SampleBlank03	QC-Blank	0 hour	-
SA265314	SampleBlank06	QC-Blank	0 hour	-
SA265315	SampleBlank02	QC-Blank	0 hour	-
SA265316	SampleBlank01	QC-Blank	0 hour	-
SA265317	QC08	QC-Pooled	0 hour	-
SA265318	QC04	QC-Pooled	0 hour	-
SA265319	QC07	QC-Pooled	0 hour	-
SA265320	QC03	QC-Pooled	0 hour	-
SA265321	QC09	QC-Pooled	0 hour	-
SA265322	QC02	QC-Pooled	0 hour	-
SA265323	QC05	QC-Pooled	0 hour	-
SA265324	QC01	QC-Pooled	0 hour	-
SA265325	QC06	QC-Pooled	0 hour	-
SA265326	SED_Reference_Liver02	QC-Reference	0 hour	-
SA265327	IPE_Reference_Liver	QC-Reference	0 hour	-
SA265328	IPE_Reference_Liver02	QC-Reference	0 hour	-
SA265329	SED_Reference_Liver	QC-Reference	0 hour	-
SA265330	90567016809	Training	1 week of training or control time	Female
SA265331	90564016809	Training	1 week of training or control time	Female
SA265332	90560016809	Training	1 week of training or control time	Female
SA265333	90571016809	Training	1 week of training or control time	Female
SA265334	90559016809	Training	1 week of training or control time	Female
SA265335	90422016809	Training	1 week of training or control time	Male
SA265336	90430016809	Training	1 week of training or control time	Male
SA265337	90423016809	Training	1 week of training or control time	Male
SA265338	90426016809	Training	1 week of training or control time	Male
SA265339	90421016809	Training	1 week of training or control time	Male
SA265340	90578016809	Training	2 weeks of training	Female
SA265341	90585016809	Training	2 weeks of training	Female
SA265342	90581016809	Training	2 weeks of training	Female
SA265343	90576016809	Training	2 weeks of training	Female
SA265344	90587016809	Training	2 weeks of training	Female
SA265345	90441016809	Training	2 weeks of training	Male
SA265346	90439016809	Training	2 weeks of training	Male
SA265347	90450016809	Training	2 weeks of training	Male
SA265348	90444016809	Training	2 weeks of training	Male
SA265349	90449016809	Training	2 weeks of training	Male
SA265350	90410016809	Training	4 weeks of training	Female
SA265351	90412016809	Training	4 weeks of training	Female
SA265352	90416016809	Training	4 weeks of training	Female
SA265353	90406016809	Training	4 weeks of training	Female
SA265354	90420016809	Training	4 weeks of training	Female
SA265355	90292016809	Training	4 weeks of training	Male
SA265356	90283016809	Training	4 weeks of training	Male
SA265357	90280016809	Training	4 weeks of training	Male
SA265358	90281016809	Training	4 weeks of training	Male
SA265359	90289016809	Training	4 weeks of training	Male
SA265360	90251016809	Training	8 weeks of training or control time	Female
SA265361	90259016809	Training	8 weeks of training or control time	Female
SA265362	90267016809	Training	8 weeks of training or control time	Female
SA265363	90254016809	Training	8 weeks of training or control time	Female
SA265364	90258016809	Training	8 weeks of training or control time	Female
SA265365	90227016809	Training	8 weeks of training or control time	Male
SA265366	90225016809	Training	8 weeks of training or control time	Male
SA265367	90218016809	Training	8 weeks of training or control time	Male
SA265368	90223016809	Training	8 weeks of training or control time	Male
SA265369	90222016809	Training	8 weeks of training or control time	Male

Showing results 1 to 69 of 69

Showing results 1 to 69 of 69