Summary of Study ST002680

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001020. The data can be accessed directly via it's Project DOI: 10.21228/M8V97D This work is supported by NIH grant, U2C- DK119886.

See: https://www.metabolomicsworkbench.org/about/howtocite.php

This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.

Study ID	ST002680
Study Title	MoTrPAC: Endurance exercise training study in young adult rats, Tissue:Liver - Untargeted Reversed-Phase Positive
Study Summary	The goal of the endurance exercise training study in young adult rats (internal code: PASS1B-06) was to perform exercise training studies in adult (6 month) F344 rats, and from these rats collect as many tissues as feasible in order to provide high quality samples for detailed analysis by chemical analysis sites. Tissues were collected from 10-12 rats sedentary control rats concurrent with the collection of the 8-week training groups. The 8-week training group and controls were from the same cohort and same age at euthanasia (either 8). For the older age group, an additional set of controls (n=5-6) were collected with the 1-2 week training group. Rats were either sedentary or underwent an exercise training program. Rats were exercised on the rodent treadmill 5 days per week using a progressive training protocol designed to exercise the rats at approximately 70% of VO2max as outlined in the Table on the next page. Training was performed no earlier than 10:00 am and no later than 5:00 pm over 5 consecutive days per week. Training was initiated with the treadmill set at 70% of VO2 max (see tables) and 5 degrees grade for 20 minutes. The duration of exercise was increased by one minute each day until day 31 of training (start of week 7), when a duration of 50 min was reached. Speed and grade of each training session increased in larger increments due to treadmill parameters. The highest intensity and duration of training began on day 31. This intensity was maintained for the final 10 days of the protocol to ensure steady state had been achieved. If any rats were unable to perform at least 4 days of training per week they were removed from the study and euthanized. It is important to note that the starting treadmill speed varied depending on the sex and age of the rat. The initial and maximum speeds were based on VO2max measurements obtained during the pre-training testing of the compliant rats. Rats assigned to the control group followed a schedule similar to the training group. They were placed in one lane on the treadmill for 15 minutes/day, 5 days per week. The treadmill was set at 0 m/min at an incline that corresponded to the incline being used by the training group.
Institute	University of Michigan
Department	Biomedical Research Core Facilities
Laboratory	Metabolomics core
Last Name	Burant
First Name	Charles
Address	6120 Brehm Tower,1000 Wall St., Ann Arbor, MI, 48105-5714
Email	burantc@med.umich.edu
Phone	(734) 232-0842
Submit Date	2023-05-02
Num Groups	65
Total Subjects	50
Raw Data Available	Yes
Raw Data File Type(s)	TBD
Analysis Type Detail	LC-MS
Release Date	2023-10-06
Release Version	1

Select appropriate tab below to view additional metadata details:

Factors:

Subject type: Mammal; Subject species: Rattus norvegicus (Factor headings shown in green)

mb_sample_id	local_sample_id	Group	Timepoint	Sex
SA265461	90266016808	Control	8 weeks of training or control time	Female
SA265462	90245016808	Control	8 weeks of training or control time	Female
SA265463	90248016808	Control	8 weeks of training or control time	Female
SA265464	90265016808	Control	8 weeks of training or control time	Female
SA265465	90252016808	Control	8 weeks of training or control time	Female
SA265466	90217016808	Control	8 weeks of training or control time	Male
SA265467	90229016808	Control	8 weeks of training or control time	Male
SA265468	90237016808	Control	8 weeks of training or control time	Male
SA265469	90232016808	Control	8 weeks of training or control time	Male
SA265470	90239016808	Control	8 weeks of training or control time	Male
SA265471	CS00000SB-04	QC-Blank	0 hour	-
SA265472	CS00000SB-06	QC-Blank	0 hour	-
SA265473	CS00000SB-05	QC-Blank	0 hour	-
SA265474	CS00000SB-03	QC-Blank	0 hour	-
SA265475	CS00000SB-02	QC-Blank	0 hour	-
SA265476	CS00000PB-02	QC-Blank	0 hour	-
SA265477	CS00000PB-01	QC-Blank	0 hour	-
SA265478	CS00000PB-04	QC-Blank	0 hour	-
SA265479	CS00000PB-03	QC-Blank	0 hour	-
SA265480	CS00000MP-04	QC-DriftCorrection	0 hour	-
SA265481	CS00000MP-03	QC-DriftCorrection	0 hour	-
SA265482	CS00000MP-02	QC-DriftCorrection	0 hour	-
SA265483	CS00000MP-05	QC-DriftCorrection	0 hour	-
SA265484	CS00000MP-09	QC-DriftCorrection	0 hour	-
SA265485	CS00000MP-01	QC-DriftCorrection	0 hour	-
SA265486	CS00000MP-08	QC-DriftCorrection	0 hour	-
SA265487	CS00000MP-07	QC-DriftCorrection	0 hour	-
SA265488	CS00000MP-06	QC-DriftCorrection	0 hour	-
SA265489	CS0000OP0-02	QC-Pooled	0 hour	-
SA265490	CS0000OP0-05	QC-Pooled	0 hour	-
SA265491	CS0000OP0-04	QC-Pooled	0 hour	-
SA265492	CS0000OP0-03	QC-Pooled	0 hour	-
SA265493	CS0000OP0-01	QC-Pooled	0 hour	-
SA265494	CS0000OP0-06	QC-Pooled	0 hour	-
SA265495	CS0000OP0-07	QC-Pooled	0 hour	-
SA265496	CS000QCMP-03	QC-Pooled	0 hour	-
SA265497	CS000QCMP-02	QC-Pooled	0 hour	-
SA265498	CS000QCMP-01	QC-Pooled	0 hour	-
SA265499	CS000QCMP-04	QC-Pooled	0 hour	-
SA265500	CS0UMRG01-03	QC-ReCAS	0 hour	-
SA265501	CS0UMRG01-02	QC-ReCAS	0 hour	-
SA265502	CS0UMRG01-04	QC-ReCAS	0 hour	-
SA265503	CS0UMRG01-01	QC-ReCAS	0 hour	-
SA265504	CSMR80010-03	QC-Reference	0 hour	-
SA265505	CSMR80010-02	QC-Reference	0 hour	-
SA265506	CSMR80011-04	QC-Reference	0 hour	-
SA265507	CSMR80010-04	QC-Reference	0 hour	-
SA265508	CSMR80010-01	QC-Reference	0 hour	-
SA265509	CSMR80011-02	QC-Reference	0 hour	-
SA265510	CSMR80011-03	QC-Reference	0 hour	-
SA265511	CSMR80011-01	QC-Reference	0 hour	-
SA265512	90559016808	Training	1 week of training or control time	Female
SA265513	90560016808	Training	1 week of training or control time	Female
SA265514	90567016808	Training	1 week of training or control time	Female
SA265515	90571016808	Training	1 week of training or control time	Female
SA265516	90564016808	Training	1 week of training or control time	Female
SA265517	90426016808	Training	1 week of training or control time	Male
SA265518	90423016808	Training	1 week of training or control time	Male
SA265519	90430016808	Training	1 week of training or control time	Male
SA265520	90422016808	Training	1 week of training or control time	Male
SA265521	90421016808	Training	1 week of training or control time	Male
SA265522	90576016808	Training	2 weeks of training	Female
SA265523	90587016808	Training	2 weeks of training	Female
SA265524	90578016808	Training	2 weeks of training	Female
SA265525	90585016808	Training	2 weeks of training	Female
SA265526	90581016808	Training	2 weeks of training	Female
SA265527	90441016808	Training	2 weeks of training	Male
SA265528	90449016808	Training	2 weeks of training	Male
SA265529	90444016808	Training	2 weeks of training	Male
SA265530	90439016808	Training	2 weeks of training	Male
SA265531	90450016808	Training	2 weeks of training	Male
SA265532	90420016808	Training	4 weeks of training	Female
SA265533	90406016808	Training	4 weeks of training	Female
SA265534	90410016808	Training	4 weeks of training	Female
SA265535	90412016808	Training	4 weeks of training	Female
SA265536	90416016808	Training	4 weeks of training	Female
SA265537	90280016808	Training	4 weeks of training	Male
SA265538	90292016808	Training	4 weeks of training	Male
SA265539	90283016808	Training	4 weeks of training	Male
SA265540	90281016808	Training	4 weeks of training	Male
SA265541	90289016808	Training	4 weeks of training	Male
SA265542	90251016808	Training	8 weeks of training or control time	Female
SA265543	90259016808	Training	8 weeks of training or control time	Female
SA265544	90267016808	Training	8 weeks of training or control time	Female
SA265545	90258016808	Training	8 weeks of training or control time	Female
SA265546	90254016808	Training	8 weeks of training or control time	Female
SA265547	90225016808	Training	8 weeks of training or control time	Male
SA265548	90218016808	Training	8 weeks of training or control time	Male
SA265549	90222016808	Training	8 weeks of training or control time	Male
SA265550	90223016808	Training	8 weeks of training or control time	Male
SA265551	90227016808	Training	8 weeks of training or control time	Male

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Showing results 1 to 91 of 91